Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Leah M, Cook"'
Autor:
Aaqib M. Bhat, Bhopal C. Mohapatra, Haitao Luan, Insha Mushtaq, Sukanya Chakraborty, Siddhartha Kumar, Wangbin Wu, Ben Nolan, Samikshan Dutta, Matthew D. Storck, Micah Schott, Jane L. Meza, Subodh M. Lele, Ming-Fong Lin, Leah M. Cook, Eva Corey, Colm Morrissey, Donald W. Coulter, M. Jordan Rowley, Amarnath Natarajan, Kaustubh Datta, Vimla Band, Hamid Band
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract While better management of loco-regional prostate cancer (PC) has greatly improved survival, advanced PC remains a major cause of cancer deaths. Identification of novel targetable pathways that contribute to tumor progression in PC could ope
Externí odkaz:
https://doaj.org/article/5e1271695c79456bb92777ad45c70f97
Publikováno v:
Cancer Medicine, Vol 12, Iss 24, Pp 21885-21904 (2023)
Abstract Cancer is a complex and dynamic disease, initiated by a multitude of intrinsic mutations and progressed with the assistance of the tissue microenvironment, encompassed by stromal cells including immune cell infiltration. The novel finding th
Externí odkaz:
https://doaj.org/article/0663b94c6bc24eeb86a336fb6ef29613
Autor:
Catherine S. Johnson, Leah M. Cook
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
One of the greatest challenges in improving prostate cancer (PCa) survival is in designing new therapies to effectively target bone metastases. PCa regulation of the bone environment has been well characterized; however, bone-targeted therapies have
Externí odkaz:
https://doaj.org/article/a57bfdfc14e7467c9ef6f86549e00c54
Autor:
Jeremy J. McGuire, Jeremy S. Frieling, Chen Hao Lo, Tao Li, Ayaz Muhammad, Harshani R. Lawrence, Nicholas J. Lawrence, Leah M. Cook, Conor C. Lynch
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The effects of bone-marrow derived MSCs on prostate cancer cells remain unknown. Here the authors show that MSC-derived IL-28 induces prostate cancer cell apoptosis via IL-28Rα-STAT1 signalling, while acquired resistance to apoptosis is associated w
Externí odkaz:
https://doaj.org/article/61b815bbfbe3485cb1696124b372aa50
Autor:
Upendra Chalise, Mediha Becirovic-Agic, Jocelyn R. Rodriguez-Paar, Shelby R. Konfrst, Sharon D. B. de Morais, Catherine S. Johnson, Elizabeth R. Flynn, Michael E. Hall, Daniel R. Anderson, Leah M. Cook, Kristine Y. DeLeon-Pennell, Merry L. Lindsey
Publikováno v:
Journal of Cardiovascular Translational Research. 16:3-16
To identify plasma proteins that mirror current and predict future remodeling after myocardial infarction (MI), we retrospectively interrogated plasma proteomes of day (D)0 control (n = 16) and D3 MI (n = 15) from C57BL/6 J mice (20 ± 1 months). A t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39d1dd99b462d076aae68948edfab42b
https://doi.org/10.1007/s12265-022-10326-w
https://doi.org/10.1007/s12265-022-10326-w
Autor:
Nicholas T. Woods, Michael A. Hollingsworth, Fang Yu, Kurt W. Fisher, Leah M. Cook, Paul M. Grandgenett, Dominick J. DiMaio, Jean L. Grem, Thomas C. Caffrey, Diane Costanzo-Garvey, Kimiko L. Krieger, Zachary S. Wagner, Fangfang Qiao, Emalie J. Clement, Dragana Lagundžin, Henry C.-H. Law
Table S5: The protein expression matrix used for input in the Principle Component Analysis. Table S6: The list of gene ontology terms in each cluster observed in the SAFE network. Table S7: The regression coefficients and constants of each protein in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f54a6415d7ce54fadb28a36a41656b8
https://doi.org/10.1158/1078-0432.22474251.v1
https://doi.org/10.1158/1078-0432.22474251.v1
Autor:
Nicholas T. Woods, Michael A. Hollingsworth, Fang Yu, Kurt W. Fisher, Leah M. Cook, Paul M. Grandgenett, Dominick J. DiMaio, Jean L. Grem, Thomas C. Caffrey, Diane Costanzo-Garvey, Kimiko L. Krieger, Zachary S. Wagner, Fangfang Qiao, Emalie J. Clement, Dragana Lagundžin, Henry C.-H. Law
Purpose:Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease that can be separated into distinct subtypes based on molecular signatures. Identifying PDAC subtype-specific therapeutic vulnerabilities is necessary to develop precision
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18245fe79d990d12c750b74042382343
https://doi.org/10.1158/1078-0432.c.6528738
https://doi.org/10.1158/1078-0432.c.6528738
Autor:
Nicholas T. Woods, Michael A. Hollingsworth, Fang Yu, Kurt W. Fisher, Leah M. Cook, Paul M. Grandgenett, Dominick J. DiMaio, Jean L. Grem, Thomas C. Caffrey, Diane Costanzo-Garvey, Kimiko L. Krieger, Zachary S. Wagner, Fangfang Qiao, Emalie J. Clement, Dragana Lagundžin, Henry C.-H. Law
Figure S6: Protein expression and gene ontology analysis related to PDAC subtypes. Figure S7: The characterization of Protein Cluster 1. Figure S8: The characterization of Protein Cluster 2. Figure S9: The characterization of Protein Cluster 3. Figur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c4e36883853066f2ebb6d12db1554b
https://doi.org/10.1158/1078-0432.22474263.v1
https://doi.org/10.1158/1078-0432.22474263.v1
Autor:
Nicholas T. Woods, Michael A. Hollingsworth, Fang Yu, Kurt W. Fisher, Leah M. Cook, Paul M. Grandgenett, Dominick J. DiMaio, Jean L. Grem, Thomas C. Caffrey, Diane Costanzo-Garvey, Kimiko L. Krieger, Zachary S. Wagner, Fangfang Qiao, Emalie J. Clement, Dragana Lagundžin, Henry C.-H. Law
Text file containing supplementary information.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0517bddde99123ac55cf98a797d55af7
https://doi.org/10.1158/1078-0432.22474260.v1
https://doi.org/10.1158/1078-0432.22474260.v1
Autor:
Nicholas T. Woods, Michael A. Hollingsworth, Fang Yu, Kurt W. Fisher, Leah M. Cook, Paul M. Grandgenett, Dominick J. DiMaio, Jean L. Grem, Thomas C. Caffrey, Diane Costanzo-Garvey, Kimiko L. Krieger, Zachary S. Wagner, Fangfang Qiao, Emalie J. Clement, Dragana Lagundžin, Henry C.-H. Law
Table S4: The total list of peptides identified.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9806e88318e05232c3da40bede9720dc
https://doi.org/10.1158/1078-0432.22474257
https://doi.org/10.1158/1078-0432.22474257