Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Leah Houri-Zeevi"'
Publikováno v:
eLife, Vol 10 (2021)
Transgenerational inheritance of small RNAs challenges basic concepts of heredity. In Caenorhabditis elegans nematodes, small RNAs are transmitted across generations to establish a transgenerational memory trace of ancestral environments and distingu
Externí odkaz:
https://doaj.org/article/22363459ce074266ae85ed24b1648de3
Publikováno v:
Developmental Cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::307f6812c394565f25b5bffbce904a47
Autor:
Itai Antoine Toker, Itamar Lev, Yael Mor, Yael Gurevich, Doron Fisher, Leah Houri-Zeevi, Olga Antonova, Hila Doron, Sarit Anava, Hila Gingold, Lilach Hadany, Shai Shaham, Oded Rechavi
Publikováno v:
Developmental cell. 57(3)
It is unknown whether transient transgenerational epigenetic responses to environmental challenges affect the process of evolution, which typically unfolds over many generations. Here, we show that in C. elegans, inherited small RNAs control genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307f6812c394565f25b5bffbce904a47
https://pubmed.ncbi.nlm.nih.gov/35134340
https://pubmed.ncbi.nlm.nih.gov/35134340
Transgenerational inheritance of small RNAs is challenging basic concepts of heredity and achieving control over such responses is of great interest. InC. elegansnematodes, small RNAs are transmitted across generations to establish a transgenerationa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb71529fd21ebf57d1278c8649ab92ee
Autor:
Oded Rechavi, Leah Houri-Zeevi
Publikováno v:
RNA Biology
In Caenorhabditis elegans small RNAs can regulate genes across generations. The mysterious tendency of heritable RNA interference (RNAi) responses to terminate after 3–5 generations has been referred to as “the bottleneck to RNAi inheritance.”
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31be7595c67b53b0923f582f0ad3cd09
http://europepmc.org/articles/PMC5207387
http://europepmc.org/articles/PMC5207387
Autor:
Leah Houri-Zeevi, Yael Korem, Yael Dagan, Lama Awad, Hila Sheftel, Oded Rechavi, Lior Faigenbloom, Itai Antoine Toker, Luba Degani, Uri Alon
Publikováno v:
Cell. 165:88-99
In C. elegans, small RNAs enable transmission of epigenetic responses across multiple generations. While RNAi inheritance mechanisms that enable "memorization" of ancestral responses are being elucidated, the mechanisms that determine the duration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7adf2213f3ede01f3dc68f64ee5a2b
https://doi.org/10.1016/j.cell.2016.02.057
https://doi.org/10.1016/j.cell.2016.02.057
Publikováno v:
Cell
Summary Experiences trigger transgenerational small RNA-based responses in C. elegans nematodes. Dedicated machinery ensures that heritable effects are reset, but how the responses segregate in the population is unknown. We show that isogenic individ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fb071b74106207f963c921ed0a0da4
https://doi.org/10.1016/j.cell.2020.07.022
https://doi.org/10.1016/j.cell.2020.07.022
Autor:
Oded Rechavi, Sarit Anava, Gregory J. Hannon, Oliver Hobert, Wee Siong Sho Goh, Sze Yen Kerk, Leah Houri-Zeevi
Publikováno v:
Cell. 158(2):277-287
SummaryEvidence from animal studies and human famines suggests that starvation may affect the health of the progeny of famished individuals. However, it is not clear whether starvation affects only immediate offspring or has lasting effects; it is al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad50738c44e413f3e139d387f56ca68
Autor:
Oded Rechavi, Leah Houri-Zeevi
Publikováno v:
Trends in genetics : TIG. 33(1)
Small RNAs are increasingly emerging as transgenerational carriers of epigenetic information in Caenorhabditis elegans and in other organisms. Recent studies have identified factors that are required for the inheritance of small RNAs and for heritabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921eb0a5d544bc400b643d4905ad9dc7
https://pubmed.ncbi.nlm.nih.gov/27939252
https://pubmed.ncbi.nlm.nih.gov/27939252