Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Leah Fitzsimmons"'
Autor:
Leah Fitzsimmons, Gemma L. Kelly
Publikováno v:
Viruses, Vol 9, Iss 11, p 339 (2017)
Epstein–Barr virus (EBV) was first discovered in cells from a patient with Burkitt lymphoma (BL), and is now known to be a contributory factor in 1–2% of all cancers, for which there are as yet, no EBV-targeted therapies available. Like other her
Externí odkaz:
https://doaj.org/article/f4a3fdcf202b4c2c9072d6c71d57cdda
Autor:
Jianmin Zuo, Wendy A Thomas, Tracey A Haigh, Leah Fitzsimmons, Heather M Long, Andrew D Hislop, Graham S Taylor, Martin Rowe
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002455 (2011)
Evasion of immune T cell responses is crucial for viruses to establish persistence in the infected host. Immune evasion mechanisms of Epstein-Barr virus (EBV) in the context of MHC-I antigen presentation have been well studied. In contrast, viral int
Externí odkaz:
https://doaj.org/article/6178491b1d0b40d1affd8e3e2c1c67a4
Autor:
Gemma L. Kelly, Marc Kvansakul, Clare Shannon-Lowe, Rosemary J. Tierney, Martin Rowe, Alan B. Rickinson, Laura C. A. Galbraith, D. Croom-Carter, Marco J Herold, Catherine Chang, Grant Dewson, Peter M. Colman, Rachel Cartlidge, Nenad Sejic, Andrew I. Bell, Andreas Strasser, Leah Fitzsimmons, David C.S. Huang, Chathura D. Suraweera
Publikováno v:
Cell Death Differ
Epstein–Barr virus (EBV), which is ubiquitous in the adult population, is causally associated with human malignancies. Like many infectious agents, EBV has evolved strategies to block host cell death, including through expression of viral homologue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8961400ef841ed9c400246b31e8c250c
https://europepmc.org/articles/PMC7206097/
https://europepmc.org/articles/PMC7206097/
Autor:
Leah, Fitzsimmons, Andrew J, Boyce, Wenbin, Wei, Catherine, Chang, Deborah, Croom-Carter, Rosemary J, Tierney, Marco J, Herold, Andrew I, Bell, Andreas, Strasser, Gemma L, Kelly, Martin, Rowe
Publikováno v:
Cell Death and Differentiation
While the association of Epstein–Barr virus (EBV) with Burkitt lymphoma (BL) has long been recognised, the precise role of the virus in BL pathogenesis is not fully resolved. EBV can be lost spontaneously from some BL cell lines, and these EBV-loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a80451670f6afea75e0bed658ea69eaa
https://pubmed.ncbi.nlm.nih.gov/28960205
https://pubmed.ncbi.nlm.nih.gov/28960205
Autor:
Gemma L. Kelly, Martin Rowe, Richard Amoroso, Leah Fitzsimmons, Andrew I. Bell, Wendy A. Thomas
Publikováno v:
Journal of Virology. 85:996-1010
Epstein-Barr virus (EBV) has been shown to encode at least 40 microRNAs (miRNAs), an important class of molecules that negatively regulate the expression of many genes through posttranscriptional mechanisms. Here, we have used real-time PCR assays to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a7e2d542c40bd423acafa7e4fbfc5c
https://doi.org/10.1128/jvi.01528-10
https://doi.org/10.1128/jvi.01528-10
Autor:
Leah Fitzsimmons
Publikováno v:
The Lancet. Infectious diseases. 15(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d57b61936ca4c42d8458490ac74a5131
https://pubmed.ncbi.nlm.nih.gov/26363597
https://pubmed.ncbi.nlm.nih.gov/26363597
Autor:
Gemma L. Kelly, Leah Fitzsimmons
Publikováno v:
Viruses, Vol 9, Iss 11, p 339 (2017)
Viruses
Viruses
Epstein–Barr virus (EBV) was first discovered in cells from a patient with Burkitt lymphoma (BL), and is now known to be a contributory factor in 1–2% of all cancers, for which there are as yet, no EBV-targeted therapies available. Like other her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f21c5792008b60b15967092b5c63fd
https://doi.org/10.3390/v9110339
https://doi.org/10.3390/v9110339
Autor:
Leah Fitzsimmons
Publikováno v:
The Lancet Gastroenterology & Hepatology. 2:160
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38d70f993c1a4eac13d03c444a186473
https://doi.org/10.1016/s2468-1253(16)30216-3
https://doi.org/10.1016/s2468-1253(16)30216-3
Publikováno v:
Chinese Journal of Cancer
In 1964, a new herpesvirus, Epstein-Barr virus (EBV), was discovered in cultured tumor cells derived from a Burkitt lymphoma (BL) biopsy taken from an African patient. This was a momentous event that reinvigorated research into viruses as a possible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c2f3582abc3df7c9c68d409d3526cd
https://doi.org/10.5732/cjc.014.10190
https://doi.org/10.5732/cjc.014.10190
Publikováno v:
Virology
We have validated a flexible, high-throughput and relatively inexpensive RT-QPCR array platform for absolute quantification of Epstein–Barr virus transcripts in different latent and lytic infection states. Several novel observations are reported. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b0c05f203724f899c40a83952cf8264
https://pubmed.ncbi.nlm.nih.gov/25463610
https://pubmed.ncbi.nlm.nih.gov/25463610