Výsledky vyhledávání - "Leah E. Hendrick"

Adherence to neoadjuvant therapy guidelines for locally advanced rectal cancers in a region with sociodemographic disparities

Autor: Jeremiah L. Deneve, Justin J. Monroe, Evan S. Glazer, David Shibata, Leah E. Hendrick, Paxton V. Dickson, Denise L. Wong, Nathan M. Hinkle, Whitney M. Guerrero

Publikováno v: The American Journal of Surgery. 222:395-401

BACKGROUND Practice guidelines recommend neoadjuvant chemoradiation (NCR) for locally advanced rectal cancer (LARC). We examined guideline adherence in a healthcare system serving a region with socioeconomic disparities and poor cancer outcomes. METH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e850855770e528ee0d8161cbe4336576
https://doi.org/10.1016/j.amjsurg.2020.11.049

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Role of TGF-β in pancreatic ductal adenocarcinoma progression and PD-L1 expression

Autor: Marcus A. Alvarez, Lorraine M. Albritton, David Shibata, Ajeeth K. Pingili, Jeremiah L. Deneve, Rita Kansal, D. Neil Hayes, Evan S. Glazer, S. Mazher Hussain, Danny Yakoub, Gustavo A. Miranda-Carboni, Leah E. Hendrick, Michio Kurosu, TJ Hollingsworth, Paxton V. Dickson, Liza Makowski, Abul Elahi

Publikováno v: Cellular Oncology. 44:673-687

The transforming growth factor-beta (TGF-β) pathway plays a paradoxical, context-dependent role in pancreatic ductal adenocarcinoma (PDAC): a tumor-suppressive role in non-metastatic PDAC and a tumor-promotive role in metastatic PDAC. We hypothesize

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e119ce96854bdf1ec19ef3ae0a06423
https://doi.org/10.1007/s13402-021-00594-0

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Characterization of epigenomic alterations in HPV16+ head and neck squamous cell carcinomas

Autor: Anders Berglund, Clarisse Muenyi, Erin M. Siegel, Abidemi Ajidahun, Steven A. Eschrich, Denise Wong, Leah E. Hendrick, Ryan M. Putney, Sungjune Kim, D. Neil Hayes, David Shibata

Publikováno v: Cancer Epidemiol Biomarkers Prev

Background: Epigenetic changes associated with human papillomavirus (HPV)–driven tumors have been described; however, HPV type–specific alterations are less well understood. We sought to compare HPV16-specific methylation changes with those in vi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303729cc8402863cafbbea90009c362e
https://europepmc.org/articles/PMC8983563/

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Early Postoperative Extubation is Associated with Shorter Hospitalization and Improved Short-Term Survival in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

Autor: Leah E. Hendrick, Xin Huang, William P. Hewgley, Luke Douthitt, Paxton V. Dickson, Evan S. Glazer, Stephen W. Behrman, David Shibata, Jeremiah L. Deneve

Publikováno v: The American surgeon. 88(5)

Background Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) is associated with significant operative time, hospital resources, and morbidity. We examine factors associated with hospital length of stay (LOS) and early ov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0287709753c24658f90b6b7d9d39f744
https://pubmed.ncbi.nlm.nih.gov/35012359

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Restaging Patients with Rectal Cancer Following Neoadjuvant Chemoradiation: A Systematic Review

Autor: Leah E. Hendrick, Renee L. Levesque, Jeremiah L. Deneve, Nathan M. Hinkle, David Shibata, Danny Yakoub, Paxton V. Dickson, Evan S. Glazer, Justin J. Monroe

Publikováno v: World Journal of Surgery. 44:973-979

In the USA, most patients with clinical stage II/III rectal cancer receive neoadjuvant chemoradiation (chemo/XRT) over 5–6 weeks followed by a 6–10-week break before proctectomy. As chemotherapy is delivered at radio-sensitizing doses, there is e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adffb8cbd04f5617f4b9a4ce5a5471bc
https://doi.org/10.1007/s00268-019-05309-z

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Visceral angiosarcoma: A nationwide analysis of treatment factors and outcomes

Autor: Leah E. Hendrick, Benjamin R. Zambetti, Denise L. Wong, Paxton V. Dickson, Evan S. Glazer, David Shibata, Martin D. Fleming, Miriam Tsao, David C. Portnoy, Jeremiah L. Deneve

Publikováno v: Journal of surgical oncologyREFERENCES. 125(8)

Visceral angiosarcoma is rare and aggressive, accounting for 2% of soft tissue sarcomas. Using a national data set, we examine determinants of outcomes for patients presenting with this rare disease.The 2004-2015 National Cancer Database was queried

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32974e298ea3b49d82d7a90e2481b8fa
https://pubmed.ncbi.nlm.nih.gov/35234280

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Chimney-Patch Arterial Graft in Kidney or Pancreas Transplantation for Recipients with Heavily Calcified Iliac Arteries

Autor: Jason M. Vanatta, Leah E. Hendrick, Ryan A. Helmick, Charles L. Mesh, Nosratollah Nezakatgoo

Publikováno v: Annals of Transplantation

Iliac artery calcification is a common phenomenon complicating renal transplantation, particularly in those with diabetes. The potential for vascular clamp injury can threaten the renal allograft, ipsilateral lower extremity, or both. Utilization of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5e044869d57f589059e6328b8d61a7
https://doi.org/10.12659/aot.912744

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What Is the Utility of Restaging Imaging for Patients With Clinical Stage II/III Rectal Cancer After Completion of Neoadjuvant Chemoradiation and Prior to Proctectomy?

Autor: Justin J. Monroe, Paxton V. Dickson, Nathan M. Hinkle, David Shibata, Jacob D Buckner, Evan S. Glazer, Jeremiah L. Deneve, Whitney M. Guerrero, Leah E. Hendrick

Publikováno v: The American surgeon. 87(2)

Background In the United States, patients with clinical stage II or III rectal cancer typically receive neoadjuvant chemoradiation therapy (chemo/XRT) over a 5-6 week period followed by a 6-10 week break prior to proctectomy. In the current study, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27aec7996f5a832a8e8180a972469f51
https://pubmed.ncbi.nlm.nih.gov/32927959

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HPP1 Ectodomain Shedding is Mediated by ADAM17 and is Necessary for Tumor Suppression in Colon Cancer

Autor: David Shibata, Jonathan M. Hernandez, Abidemi Ajidahun, Abul Elahi, Leah E. Hendrick, Irina Getun, Leigh Ann Humphries

Publikováno v: J Surg Res

Background Hyperplastic polyposis protein 1 (HPP1) encodes a tumor-suppressive transmembrane cleavable epidermal growth factor–like ligand. It is unclear as to whether cleavage and shedding of HPP1 are essential steps in achieving its tumor suppres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e986af6cb9244c08d190768346de946
https://europepmc.org/articles/PMC7483406/

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