Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Leah Conroy"'
Autor:
R. Yamamoto, Leah Conroy, J. Lyons, S. Munemitsu, Yasuo Takeda, R. Clark, J. Schreurs, James E. Krause, M. Innis
Publikováno v:
Journal of Neurochemistry. 64:1622-1631
The rat substance P (SP) receptor (SPR) was expressed in insect Sf9 cells by infection with recombinant baculovirus. The receptor bound SP with high affinity (KD = 360 pM) and had a rank order of affinity of SP > neurokinin A > neurokinin B. Ligand a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87da2cb07cc36e235c9aa4ab6fa5a2f
https://doi.org/10.1046/j.1471-4159.1995.64041622.x
https://doi.org/10.1046/j.1471-4159.1995.64041622.x
Autor:
Bonnee Rubinfeld, Walter J. Crosier, Iris Albert, Leah Conroy, Robin Clark, Frank Mccormick, Paul Polakis
Publikováno v:
Molecular and Cellular Biology. 12:4634-4642
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbf3bd1434523b91e325e09d41eebb90
https://doi.org/10.1128/mcb.12.10.4634-4642.1992
https://doi.org/10.1128/mcb.12.10.4634-4642.1992
Autor:
Robin Clark, Leah Conroy, Frank McCormick, Oliver Müller, Paul G. Polakis, Gail L. Wong, Michael Moran
Publikováno v:
Cell. 69:551-558
p62 is a tyrosine phosphoprotein that associates with p21ras GTPase-activating protein (GAP). Purification and cDNA cloning of p62 reveal extensive sequence similarity to a putative hnRNP protein, GRP33. Recombinant human p62 purified from insect Sf9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7923677e4390de18485e105fd86516ef
https://doi.org/10.1016/0092-8674(92)90455-l
https://doi.org/10.1016/0092-8674(92)90455-l
Autor:
Kenneth W.K. Watt, Susan Munemitsu, Frank McCormick, Bonnee Rubinfeld, Robin D. Clark, Paul G. Polakis, Walter J. Crosier, Leah Conroy
Publikováno v:
Cell. 65:1033-1042
The rap1 /K rev -1 gene encodes a ras-related protein that suppresses transformation by ras oncogenes. We have purified an 88 kd GTPase activating protein (GAP), specific for the rap1 /K rev -1 gene product, from bovine brain. Based on partial amino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4cee69a55e5cefa0221e23fcf01d69
https://doi.org/10.1016/0092-8674(91)90555-d
https://doi.org/10.1016/0092-8674(91)90555-d
Autor:
Frank McCormick, Robin D. Clark, George A. Martin, Atsuko Yatani, Paul G. Polakis, Arthur M. Brown, Leah Conroy
Publikováno v:
Science. 255:192-194
The interaction between the low molecular weight G protein ras p21 and a guanosine triphosphatase activating protein (GAP) uncouples a heterotrimeric G protein (Gk) from muscarinic receptors. Through the use of isolated atrial cell membranes and gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebd09f56eca30ee95e992fa39333fe2
https://doi.org/10.1126/science.1553544
https://doi.org/10.1126/science.1553544
Publikováno v:
The Journal of biological chemistry. 271(1)
The phosphotyrosine binding (PTB) domain specifically binds to tyrosine-phosphorylated proteins, but differs in structure and mechanism of action from the SH2 domain family. We quantitated the affinity, specificity, and kinetics of the interaction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c672358ae6769af94adbe61011c15299
https://pubmed.ncbi.nlm.nih.gov/8550571
https://pubmed.ncbi.nlm.nih.gov/8550571
Publikováno v:
Journal of immunological methods. 152(1)
We have expressed human CD40 and human B7 in insect cells using the baculovirus expression system and have used these insect cells to immunize mice for the generation of monoclonal antibodies. We demonstrate here that specific monoclonal antibodies t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cafc1cdece4f22abadc56cd8543fe9a
https://pubmed.ncbi.nlm.nih.gov/1379275
https://pubmed.ncbi.nlm.nih.gov/1379275
Autor:
Gideon Bollag, Richard M. Cawthon, Jeff Stevens, Eitan Friedman, Frank McCormick, Leah Conroy, Robin Clark, Ying Li, Ray White, Wade S. Samowitz, Margaret Robertson, Daniel W. Fults, Paige Bradley, Kenneth Ward
Publikováno v:
Cell. 69(2)
The neurofibromatosis 1 (NF1) gene product, neurofibromin, contains a GTPase-activating protein (GAP)-related domain, or NF1 GRD, that is able to down-regulate p21ras by stimulating its intrinsic GTPase. Since p21ras.GTP is a major regulator of growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f9ecc9bcc544c6f9558d7e82f3c696
https://pubmed.ncbi.nlm.nih.gov/1568247
https://pubmed.ncbi.nlm.nih.gov/1568247
Autor:
George A. Martin, Robin D. Clark, Michael A. Innis, Leah Conroy, Gideon Bollag, Walter J. Crosier, David Viskoohil, Frank McCormick, Peter C. McCabe, Richard M. Cawthon, Heinz Haubruck, Peter O'Connell
Publikováno v:
Cell. 63(4)
The neurofibromatosis type 1 (NF1) protein contains a region of significant sequence similarity to ras p21 GTPase-activating protein (GAP) and the yeast IRA1 gene product. A fragment of NF1 cDNA encoding the GAP-related domain (NF1 GRD) was expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5759bfc668014d3bd91b581501a0a5
https://pubmed.ncbi.nlm.nih.gov/2121370
https://pubmed.ncbi.nlm.nih.gov/2121370
Autor:
Heather MacDonald, Robert Halenbeck, Anne Roulston, Leah Conroy, Timothy T. Chen, Lewis T. Williams
Publikováno v:
Current Biology. (9):537-S1
Induction of apoptosis by death receptors such as Fas or tumour necrosis factor (TNF) R1 leads to distinct changes in cell morphology, activation of the caspase protease cascade, and the degradation of nuclear chromatin by activated nucleases. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53dfccf3aa83786e9e02da8fd234fbab