Zobrazeno 1 - 10
of 5 134
pro vyhledávání: '"Leah C"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Caffeine is a widely consumed stimulant with dose-dependent effects on behavior. Across species, lower doses tend be anxiolytic and increase activity, while higher doses tend to be anxiogenic and decrease activity. Given the importance of th
Externí odkaz:
https://doaj.org/article/15f032ce407d42a48b8bf3c57c62b453
Autor:
Kaili Chen, Adrian Najer, Patrick Charchar, Catherine Saunders, Chalaisorn Thanapongpibul, Anna Klöckner, Mohamed Chami, David J. Peeler, Inês Silva, Luca Panariello, Kersti Karu, Colleen N. Loynachan, Leah C. Frenette, Michael Potter, John S. Tregoning, Ivan P. Parkin, Andrew M. Edwards, Thomas B. Clarke, Irene Yarovsky, Molly M. Stevens
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Staphylococcus aureus is a leading cause of nosocomial implant-associated infections, causing significant morbidity and mortality, underscoring the need for rapid, non-invasive, and cost-effective diagnostics. Here, we optimise the synthesis
Externí odkaz:
https://doaj.org/article/cce09cda3cc44bc1a4d83bbce5d35001
Autor:
Janet O. Joseph, Michelle Ylade, Jedas Veronica Daag, Rosemary Aogo, Maria Vinna Crisostomo, Patrick Mpingabo, Lakshmanane Premkumar, Jacqueline Deen, Leah C. Katzelnick
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background SARS-CoV-2, the causative agent of COVID-19, is a betacoronavirus belonging to the same genus as endemic human coronaviruses (hCoVs) OC43 and HKU1 and is distinct from alpha hCoVs 229E and NL63. In a study of adolescents in the Ph
Externí odkaz:
https://doaj.org/article/fedcf296de784962b289d0b2cf65a37e
Autor:
Paul Trlin, Jenny Gong, Katie K. N. Tran, Vickie H. Y. Wong, Pei Ying Lee, Anh Hoang, Da Zhao, Leah C. Beauchamp, Jeremiah K. H. Lim, Andrew Metha, Kevin J. Barnham, David I. Finkelstein, Bang V. Bui, Phillip Bedggood, Christine T. O. Nguyen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Retinal hyperspectral imaging (HSI) is a non-invasive in vivo approach that has shown promise in Alzheimer’s disease. Parkinson’s disease is another neurodegenerative disease where brain pathobiology such as alpha-synuclein and iron over
Externí odkaz:
https://doaj.org/article/4922d8416bbd4e5ca8336a9df43afadf
Publikováno v:
Frontiers in Education, Vol 9 (2024)
In recent years, the idea that cohorts can prepare public health students for successful careers and professional development has been increasingly studied by researchers and educators. Previous literature suggests that cohorts can improve learning o
Externí odkaz:
https://doaj.org/article/0191e65867a1417e980677f24bd7a913
Autor:
Bala S.C. Koritala, Sreeja Parameswaran, Omer A. Donmez, Carmy Forney, Hope Rowden, Charles A. Moore, Angela L. Duggins, Alexandra Sestito, Brittany A. Leader, Matthew T. Weirauch, Leah C. Kottyan, David F. Smith
Publikováno v:
Heliyon, Vol 10, Iss 23, Pp e40830- (2024)
Obstructive Sleep Apnea (OSA) is a common sleep-related breathing disorder characterized by airway obstruction during sleep. Diagnosing pediatric OSA is challenging, particularly in underrepresented populations, leading to disparities in treatment an
Externí odkaz:
https://doaj.org/article/018901c1e5fb4334b9a7724c13c0d97a
Autor:
Sanjida Mir, Ryan J. Keenan, Romke Bron, Cameron J. Nowell, Catriona McLean, Leah C. Beauchamp, Laura J. Vella, Brian Dean, Daniel Hoyer, Laura H. Jacobson
Publikováno v:
Medicine in Drug Discovery, Vol 24, Iss , Pp 100202- (2024)
Hypocretin (Hcrtr, HCRTR) / orexin (OX) receptors modulate a range of neurobiological functions and are drug targets for several disorders. Mapping the distribution of receptors in the brain can inform their function and guide targeting of specific d
Externí odkaz:
https://doaj.org/article/9f4c6bbb7e4a49a9a8786c108d2f560f
Autor:
Giordano de Guglielmo, Lieselot Carrette, Marsida Kallupi, Molly Brennan, Brent Boomhower, Lisa Maturin, Dana Conlisk, Sharona Sedighim, Lani Tieu, McKenzie J Fannon, Angelica R Martinez, Nathan Velarde, Dyar Othman, Benjamin Sichel, Jarryd Ramborger, Justin Lau, Jenni Kononoff, Adam Kimbrough, Sierra Simpson, Lauren C Smith, Kokila Shankar, Selene Bonnet-Zahedi, Elizabeth A Sneddon, Alicia Avelar, Sonja Lorean Plasil, Joseph Mosquera, Caitlin Crook, Lucas Chun, Ashley Vang, Kristel K Milan, Paul Schweitzer, Bonnie Lin, Beverly Peng, Apurva S Chitre, Oksana Polesskaya, Leah C Solberg Woods, Abraham A Palmer, Olivier George
Publikováno v:
eLife, Vol 12 (2024)
Addiction is commonly characterized by escalation of drug intake, compulsive drug seeking, and continued use despite harmful consequences. However, the factors contributing to the transition from moderate drug use to these problematic patterns remain
Externí odkaz:
https://doaj.org/article/1923f5bd1caa4a8a8be0945efcb68338
Autor:
Guillermo Najarro, Kevin Brackett, Hunter Woosley, Leah C Dorman, Vincent Turon-Lagot, Sudip Khadka, Catya Faeldonea, Osvaldo Kevin Moreno, Adriana Ramirez Negron, Christina Love, Ryan Ward, Charles Langelier, Frank McCarthy, Carlos Gonzalez, Joshua E Elias, Brooke M Gardner, Carolina Arias
Publikováno v:
PLoS Pathogens, Vol 20, Iss 10, p e1012660 (2024)
The Endoplasmic Reticulum (ER)-resident HSP70 chaperone BiP (HSPA5) plays a crucial role in maintaining and restoring protein folding homeostasis in the ER. BiP's function is often dysregulated in cancer and virus-infected cells, conferring pro-oncog
Externí odkaz:
https://doaj.org/article/ba9d798e7041468bbfff37dc0d7d585d
Autor:
Victoria Ledbetter, Scott Auerbach, Logan J. Everett, Beena Vallanat, Anna Lowit, Gregory Akerman, William Gwinn, Leah C. Wehmas, Michael F. Hughes, Michael Devito, J. Christopher Corton
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Current methods for cancer risk assessment are resource-intensive and not feasible for most of the thousands of untested chemicals. In earlier studies, we developed a new approach methodology (NAM) to identify liver tumorigens using gene expression b
Externí odkaz:
https://doaj.org/article/b05c465a5b4645b5b3f97f1d7d895f25