Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Leah B. Doughty"'
Publikováno v:
Synthetic and Systems Biotechnology, Vol 3, Iss 4, Pp 268-274 (2018)
FK228 is an FDA-approved anticancer drug naturally produced by Chromobacterium violaceum No. 968 up to 19 mg/L in a pilot industry-scale batch fermentation. Here we report a genomics-guided discovery of Burkholderia thailandensis MSMB43 as a new and
Externí odkaz:
https://doaj.org/article/566d1475a31c42c9be4d781e14d394e3
Publikováno v:
Synthetic and Systems Biotechnology, Vol 3, Iss 4, Pp 268-274 (2018)
Synthetic and Systems Biotechnology
Synthetic and Systems Biotechnology
FK228 is an FDA-approved anticancer drug naturally produced by Chromobacterium violaceum No. 968 up to 19 mg/L in a pilot industry-scale batch fermentation. Here we report a genomics-guided discovery of Burkholderia thailandensis MSMB43 as a new and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4dd685827340614d6a3ba9b93bc6c43
https://doi.org/10.1016/j.synbio.2018.10.011
https://doi.org/10.1016/j.synbio.2018.10.011
Autor:
Franz-Josef Meyer-Almes, Leonhard M. Henkes, Yi-Qiang Cheng, Difei Wang, Cheng Wang, Min He, Leah B. Doughty
Publikováno v:
Journal of natural products. 74(10)
Histone deacetylase (HDAC) inhibitors have emerged as a new class of anticancer drugs, with one synthetic compound, SAHA (vorinostat, Zolinza®; 1), and one natural product, FK228 (depsipeptide, romidepsin, Istodax®; 2), approved by FDA for clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fbe02abeb110dcd7d12b335a8177aa4
https://pubmed.ncbi.nlm.nih.gov/21793558
https://pubmed.ncbi.nlm.nih.gov/21793558
Autor:
Cheng Wang, Leah B. Doughty, Difei Wang, David J. Newman, Franz-Josef Meyer-Almes, Leonhard M. Henkes, Yi-Qiang Cheng, Min He
Publikováno v:
Cancer Research. 71:5418-5418
Epigenetic abnormalities participate with genetic mutations to cause cancer; consequently epigenetic intervention of cancer has emerged as a promising avenue toward cancer therapy, with one synthetic compound verinostat (SAHA, Zolinza® by Merck & Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adfebcb25fad159d9dfe7ea6fd8e77ff
https://doi.org/10.1158/1538-7445.am2011-5418
https://doi.org/10.1158/1538-7445.am2011-5418