EEG pre-burst suppression: characterization and inverse association with preoperative cognitive function in older adults

Autor: Melody Reese, Soren Christensen, Harel Anolick, Kenneth C. Roberts, Megan K. Wong, Mary Cooter Wright, Leah Acker, Jeffrey N. Browndyke, Marty G. Woldorff, Miles Berger, the MADCO-PC and INTUIT Investigators, O Akinyemi, CL Amundsen, P Avasarala, M Barber, R Beach, S Bengali, E Bennett, A Berchuck, MF Berry, DG Blazer, MP Bolognesi, R Brassard, BE Brigman, JN Browndyke, M Bullock, T Bunning, A Burke, V Cai, J Carter, J Chapman, C Chen, V Cheong, S Christensen, HJ Cohen, B Colin, C Colon-Emeric, M Cooter, M Cox, D Crabtree, B Davidson, JK DeOrio, M Devinney, TA D’Amico, ME Easley, E Ehieli, T Ellett, D Erdmann, RM Esclamado, M Ferrandino, B Funk, J Gadsden, J Gardner, G Garrigues, C Giattino, DT Gold, S Grant, R Greenup, J Guercio, DK Gupta, A Habib, RK Hallows, DH Harpole, SM Harris, MG Hartwig, L Havrilesky, T Henley, C Holland, ST Hollenbeck, J Hu, R Huang, E Iboaya, BA Inman, DW Jang, J Kaisen, A Kawasaki, A Khan, J Klapper, S Lagoo-Deenadayalan, DT Laskowitz, PS Lee, WT Lee, J Lemm, H Levinson, ME Lipkin, H Litchfield, CR Mantyh, E Marlor, KT Martucci, J Mathew, C Maxwell, DL McDonagh, J Migaly, SK Mithani, E Moretti, P Mosca, J Moul, D Murdoch, MF Newman, K Ni, T Novick, B Ohlendorf, S Olson, MW Onaitis, D Oyeyemi, TN Pappas, GL Pellom, AN Perez, AC Peterson, A Podgoreanu, TJ Polascik, P Potash, GM Preminger, R Previs, Q Quinones, EN Rampersaud, A Ray, A Renne, K Roberts, CN Robertson, SA Roman, S Runyon, E Sanders, A Sandler, F Sbahi, CD Scales, RP Scheri, K Seymour, S Smani, SK Smith, M Stang, S Stanley, K Sweeney, A Syed, A Szydlowska, L Talbot, N Terrando, JKM Thacker, J Thomas, BC Tong, Y Toulgoat-Dubois, A Tu, SN Vaslef, N Waldron, X Wang, DS Warner, K Weinhold, SS Wellman, H Whitson, T Wickenheisser, D Williams, M Woldorff, MK Wong, C Young, S Zani

Publikováno v: Frontiers in Aging Neuroscience, Vol 15 (2023)

The most common complication in older surgical patients is postoperative delirium (POD). POD is associated with preoperative cognitive impairment and longer durations of intraoperative burst suppression (BSup) – electroencephalography (EEG) with re

Externí odkaz: https://doaj.org/article/93500dbf0366414a890d2a69aa098aea

Conserved YKL-40 changes in mice and humans after postoperative delirium

Autor: Jennifer David-Bercholz, Leah Acker, Ana I. Caceres, Pau Yen Wu, Saanvi Goenka, Nathan O. Franklin, Ramona M. Rodriguiz, William C. Wetsel, Michael Devinney, Mary Cooter Wright, Henrik Zetterberg, Ting Yang, Miles Berger, Niccolò Terrando

Publikováno v: Brain, Behavior, & Immunity - Health, Vol 26, Iss , Pp 100555- (2022)

Delirium is a common postoperative neurologic complication among older adults. Despite its prevalence (14%–50%) and likely association with inflammation, the exact mechanisms that underpin postoperative delirium are unclear. This project aimed to c

Externí odkaz: https://doaj.org/article/8d70360632ce4270a544a9df0d5c7ba8

Postoperative changes in cognition and cerebrospinal fluid neurodegenerative disease biomarkers

Autor: Miles, Berger, Jeffrey N, Browndyke, Mary, Cooter Wright, Chloe, Nobuhara, Melody, Reese, Leah, Acker, W Michael, Bullock, Brian J, Colin, Michael J, Devinney, Eugene W, Moretti, Judd W, Moul, Brian, Ohlendorf, Daniel T, Laskowitz, Teresa, Waligorska, Leslie M, Shaw, Heather E, Whitson, Harvey J, Cohen, Joseph P, Mathew, S, Zani

Publikováno v: Annals of clinical and translational neurology. 9(2)

Numerous investigators have theorized that postoperative changes in Alzheimer's disease neuropathology may underlie postoperative neurocognitive disorders. Thus, we determined the relationship between postoperative changes in cognition and cerebrospi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32d6900386ca8a7f41e73db5c6d8544
https://pubmed.ncbi.nlm.nih.gov/35104057

Perioperative Management of Flecainide: A Problem-Based Learning Discussion

Autor: Colleen Naglee, Yuriy S. Bronshteyn, Kristen Bova Campbell, Brad M. Taicher, Leah Acker

Publikováno v: AA practice. 15(4)

Flecainide is a first-line antiarrhythmic drug used to treat atrial arrhythmias and/or supraventricular tachycardia in those without coronary artery disease or structural heart disease. Even though it is an older antiarrhythmic, flecainide accounted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742eb85f7ef1e0bed33ac15a7fb3fcd8
https://pubmed.ncbi.nlm.nih.gov/33793430

An Open Resource for Non-human Primate Optogenetics

Autor: Wolfram Schultz, Marc Alwin Gieselmann, Giacomo Benvenuti, Daniel L. Albaugh, Masahiko Takada, Christopher I. Petkov, Azadeh Yazdan-Shahmorad, Mark A.G. Eldridge, Francesco Fabbrini, Roberto Calcedo, Krishna V. Shenoy, Karl Deisseroth, Leah Acker, Naotaka Fujii, Spencer C Chen, Masayuki Matsumoto, Adam Kohn, Eyal Seidemann, Adriana Galván, Janina Hüer, Samantha Debes, Eghbal A. Hosseini, Selina S. Solomon, Haoran Xu, Philip N. Sabes, Xing Hu, Caitlin R. Siu, James Cavanaugh, Hidetoshi Amita, Seth W. Egger, Arash Afraz, Yuzhi Chen, Diego Mendoza-Halliday, Ken-ichi Inoue, Evan D. Remington, Thomas Wichmann, Wim Vanduffel, Niansheng Ju, Christopher R. Fetsch, Michael Ortiz-Rios, Sorin Pojoga, Michele A. Basso, Carsten Klein, Hala G. El-Nahal, Roberto A. Gulli, Robert H. Wurtz, Rundong Jiang, John L. Spudich, Yoland Smith, Charu Ramakrishnan, Ji Dai, Supriya Ghosh, Yann Suhan Senova, Alexander Thiele, John H. R. Maunsell, Matthew P. Whitmire, Frederick Federer, David L. Sheinberg, Kazutaka Maeda, Robert Desimone, Mehrdad Jazayeri, Marc A. Sommer, Sébastien Tremblay, Michael C. Schmid, Shiming Tang, Kohitij Kar, Rishi Rajalingham, Andrew M. Clark, Okihide Hikosaka, Michael J. Caiola, Michal G. Fortuna, Ross S. Muers, Richard C. Saunders, Alexander Gail, Hansjörg Scherberger, Stéphane Palfi, Roger Janz, Michael N. Shadlen, Robert M. Friedman, Puiu F. Balan, Cambria Revsine, William R. Stauffer, Misako Komatsu, Ilya E. Monosov, Martin O. Bohlen, Stefan Treue, Lauri Nurminen, Michael L. Platt, Alessandra Angelucci, Mykyta M. Chernov, James J. DiCarlo, Daniel J. O’Shea, Anna W. Roe, Rufin Vogels, Julio Martinez-Trujillo, Valentin Dragoi, Amir Aschner, Ariana R. Andrei

Publikováno v: Neuron
Physiology and Pharmacology Publications

Optogenetics has revolutionized neuroscience in small laboratory animals, but its effect on animal models more closely related to humans, such as non-human primates (NHPs), has been mixed. To make evidence-based decisions in primate optogenetics, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b1acc1259f0ac65a1d2c45be564151
https://doi.org/10.1016/j.neuron.2020.09.027