Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Leading Off"'
Publikováno v:
Inflamm Bowel Dis
Intestinal fibrosis is a late-stage phenotype of inflammatory bowel disease (IBD), which underlies most of the long-term complications and surgical interventions in patients, particularly those with Crohn's disease. Despite these issues, antifibrotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfdab0162431daa2572bf183820cc5ee
https://doi.org/10.1093/ibd/izab251
https://doi.org/10.1093/ibd/izab251
Autor:
Georgios V. Gkoutos, Uday N. Shivaji, Animesh Acharjee, Davide Zardo, Louisa E. Jeffery, A Bazarova, Rosanna Cannatelli, Marietta Iacucci, Olga Maria Nardone, Subrata Ghosh, Samuel C. Smith, John A. Williams
Publikováno v:
Inflammatory Bowel Diseases
Background Endoscopic and histological remission are both important treatment goals in patients with ulcerative colitis (UC). We aimed to define cellular architecture, expression of molecular markers, and their correlation with endoscopic scores asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241bc183676645127686b01ae121d049
https://doi.org/10.1093/ibd/izab059
https://doi.org/10.1093/ibd/izab059
Autor:
Jordan Weitzner, Suresh Venkateswaran, David T. Okou, Hari K. Somineni, Pankaj Chopra, Shelly Abramowicz, Subra Kugathasan, Michael E. Zwick, Cary G. Sauer, David J. Cutler, Jarod Prince, Anne Dodd, Arjuna Karikaran
Publikováno v:
Inflamm Bowel Dis
Background The gut and oral microbiome have independently been shown to be associated with inflammatory bowel disease (IBD). However, it is not known to what extent gut and oral microbial disease markers converge in terms of their composition in IBD.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da06ec3e5d7bacc1f9926e8fbf5ee91
https://doi.org/10.1093/ibd/izab082
https://doi.org/10.1093/ibd/izab082
Autor:
Suresh Venkateswaran, Thomas D. Walters, Subra Kugathasan, Cary G. Sauer, Joelynn Dailey, James Markowitz, Marian Pfefferkorn, Neal S. Leleiko, Yael Haberman, Jeffrey S. Hyams, Brendan M. Boyle, Michael Brimacombe, Robert N. Baldassano, Lee A. Denson, David R. Mack, Joel R. Rosh, Angela Mo, Anne M. Griffiths, Greg Gibson, Ashish S. Patel, Sapana Shah
Publikováno v:
Inflamm Bowel Dis
Background Develop a clinical and biological predictive model for colectomy risk in children newly diagnosed with ulcerative colitis (UC). Methods This was a multicenter inception cohort study of children (ages 4-17 years) newly diagnosed with UC tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d188d2fa6b62fb4caa0786c8a3b2bc
https://doi.org/10.1093/ibd/izab061
https://doi.org/10.1093/ibd/izab061
Publikováno v:
Inflammatory Bowel Diseases
Background Clinical indices to characterize the severity of inflammatory bowel disease (IBD) are widely used in clinical trials and real-world practice. However, there are few validated instruments for assessing IBD severity in administrative claims-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7364a6ee7961e2f9fb5cb534d5de463c
https://doi.org/10.1093/ibd/izaa263
https://doi.org/10.1093/ibd/izaa263
Autor:
Robert H. Lustig, Cheng-Shiun Leu, Stephen L. Guthery, Francisco A. Sylvester, Alka Goyal, Neera Gupta, Ashish S. Patel, Howard Andrews, Ranjana Gokhale, Leah Siebold
Publikováno v:
Inflamm Bowel Dis
Background Statural growth impairment is more common in male patients with Crohn’s disease (CD). We identified clinical variables associated with height z score differences by sex in children participating in the Growth Study, a prospective multice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6214d2e75df21f79e22a18ba17e5c624
https://doi.org/10.1093/ibd/izaa220
https://doi.org/10.1093/ibd/izaa220
Publikováno v:
Inflamm Bowel Dis
Despite major advances in the inflammatory bowel diseases field, biomarkers to enable personalized and effective management are inadequate. Disease course and treatment response are highly variable, with some patients experiencing mild disease progre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5fe4cc1e4298947039c34010f0830a
https://doi.org/10.1093/ibd/izaa210
https://doi.org/10.1093/ibd/izaa210
Autor:
Peter D.R. Higgins, Sha Huang, Laura A. Johnson, Kelly C. Cushing, Calen A. Steiner, Jeffrey A. Berinstein, Eva S. Rodansky, Jason R. Spence
Publikováno v:
Inflamm Bowel Dis
Background Fibrosis is the final common pathway to intestinal failure in Crohn’s disease, but no medical therapies exist to treat intestinal fibrosis. Activated myofibroblasts are key effector cells of fibrosis in multiple organ systems, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba8678d9b2f63edc59c0b4d6e24bdcf
https://doi.org/10.1093/ibd/izaa169
https://doi.org/10.1093/ibd/izaa169
Autor:
Arne K. Sandvik, Maya Olaisen, Elin Synnøve Røyset, Reidar Fossmark, Arnar Flatberg, Atle van Beelen Granlund, Tom C. Martinsen
Publikováno v:
Inflammatory Bowel Diseases
Background Microbiota is most likely essential in the pathogenesis of Crohn’s disease (CD). Fecal diversion after ileocecal resection (ICR) protects against CD recurrence, whereas infusion of fecal content triggers inflammation. After ICR, the majo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51fc6c0aedfb38ac8c0ab6fa7b353804
https://doi.org/10.1093/ibd/izaa107
https://doi.org/10.1093/ibd/izaa107
Autor:
Fabio Chicco, Laura Casula, Arianna Cingolani, Emanuela Urru, Mario Pesenti, Salvatore Magrì, F. Zara, D. Paduano, Alessandro Melis, Massimo Fantini, Francesca Tumbarello, Paolo Usai
Publikováno v:
Inflammatory Bowel Diseases
Background & Aims Malnutrition with the accumulation of fat tissue and nonalcoholic fatty liver disease (NAFLD) are conditions associated with inflammatory bowel disease (IBD). Visceral fat and NAFLD-related liver dysfunction can both worsen intestin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ec71876bccd8b522a2bee4e1b3c6e0
http://europepmc.org/articles/PMC7737160
http://europepmc.org/articles/PMC7737160