Minimally invasive, sustained-release relaxin-2 microparticles reverse arthrofibrosis.

Autor: Kirsch JR; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA., Williamson AK; Department of Chemistry, Boston University, Boston, MA 02215, USA., Yeritsyan D; Musculoskeletal Translational Innovation Initiative, Carl J Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA., Blessing WA; Department of Chemistry, Boston University, Boston, MA 02215, USA., Momenzadeh K; Musculoskeletal Translational Innovation Initiative, Carl J Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA., Leach TR; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA., Williamson PM; Musculoskeletal Translational Innovation Initiative, Carl J Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA., Korunes-Miller JT; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA., DeAngelis JP; Carl J Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA., Zurakowski D; Departments of Anesthesiology and Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Nazarian RM; Pathology Service, Dermatopathology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Rodriguez EK; Musculoskeletal Translational Innovation Initiative, Carl J Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.; Carl J Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA., Nazarian A; Musculoskeletal Translational Innovation Initiative, Carl J Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.; Department of Orthopaedic Surgery, Yerevan State Medical University, Yerevan 0025, Armenia., Grinstaff MW; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.; Department of Chemistry, Boston University, Boston, MA 02215, USA.

Publikováno v: Science translational medicine [Sci Transl Med] 2022 Oct 12; Vol. 14 (666), pp. eabo3357. Date of Electronic Publication: 2022 Oct 12.