Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Leabaneng, Tawe"'
Autor:
Patricia S. Rantshabeng, Billy M. Tsima, Andrew K. Ndlovu, Keneilwe Motlhatlhedi, Kirthana Sharma, Carol B. Masole, Natasha O. Moraka, Kesego Motsumi, Angela K. T. Maoto-Mokote, Alemayehu B. Eshetu, Leabaneng Tawe, Tendani Gaolathe, Sikhulile Moyo, Lynnette T. Kyokunda
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Cervical cancer remains a public health problem despite heavy global investment in health systems especially in low-and-middle-income countries (LMIC). Prophylactic vaccines against the most commonly detected human papillomavirus
Externí odkaz:
https://doaj.org/article/12fc0a6917d042c2926a439a599193a0
Autor:
Sikhulile Moyo, Doreen Ramogola-Masire, Natasha O. Moraka, Leabaneng Tawe, Farzad Noubary, Kesego Motsumi, Godiraone Manowe, Boitumelo Zuze, Botshelo Radibe, Faith T. T. Hungwe, Terence Mohammed, Comfort Maphorisa, Roger Shapiro, Simani Gaseitsiwe, Rebecca Luckett
Publikováno v:
Infectious Agents and Cancer, Vol 18, Iss 1, Pp 1-7 (2023)
Abstract Background Low- and middle-income countries (LMICs) account for nearly 85% of the global cervical cancer burden, yet have the least access to high-performance screening. International guidelines recommend human papillomavirus testing (HPV) a
Externí odkaz:
https://doaj.org/article/a46cba6b2ee64e1d90fc60e77e0be67f
Autor:
Leabaneng Tawe, Wonderful T. Choga, Giacomo M. Paganotti, Ontlametse T. Bareng, Tlhalefo D. Ntereke, Pleasure Ramatlho, Doreen Ditshwanelo, Simani Gaseitsiwe, Ishmael Kasvosve, Doreen Ramogola-Masire, Omenge E. Orang’o, Erle Robertson, Nicola Zetola, Sikhulile Moyo, Surbhi Grover, Aaron C. Ermel
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background The variation of human papillomavirus (HPV) genotypes shapes the risks of cervical cancer and these variations are not well defined in Africa. Nucleotide changes within the L1 gene, nucleotide variability, and phylogeny were explo
Externí odkaz:
https://doaj.org/article/17c764e4d1124c1d9a677ecb1f16d1a4
Autor:
Surbhi Grover, Rohini Bhatia, Tara M. Friebel-Klingner, Anikie Mathoma, Peter Vuylsteke, Salman Khan, Tlotlo Ralefala, Leabaneng Tawe, Lisa Bazzett-Matabele, Barati Monare, Rebecca Luckett, Doreen Ramogola-Masire
Publikováno v:
Cancer Treatment and Research Communications, Vol 34, Iss , Pp 100682- (2023)
Women living with HIV (WLWH) are at an increased risk of developing HPV-related high grade cervical dysplasia and cervical cancer. Prior World Health Organization (WHO) screening guidelines recommended starting screening at age 30. We assessed charac
Externí odkaz:
https://doaj.org/article/98e23c0a802b474aa7b1a9b996d21b6a
Autor:
Leabaneng Tawe, Pleasure Ramatlho, Rebecca Ketlametswe, Moses Koobotse, Erle S. Robertson, Surbhi Grover, Doreen Ramogola-Masire, Giacomo M. Paganotti
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Cervical cancer burden is still high in low- and middle-income countries, including Botswana. Persistent human papillomavirus (HPV) infection is the leading cause of cervical cancer. Accurate knowledge of HPV diversity associated to cervical cancer i
Externí odkaz:
https://doaj.org/article/f763589e8d244462a366b73fdaf76667
Autor:
Baitshepi Mokaleng, Wonderful Tatenda Choga, Ontlametse Thato Bareng, Dorcas Maruapula, Doreen Ditshwanelo, Nametso Kelentse, Patrick Mokgethi, Natasha Onalenna Moraka, Modisa Sekhamo Motswaledi, Leabaneng Tawe, Catherine Kegakilwe Koofhethile, Sikhulile Moyo, Matshediso Zachariah, Simani Gaseitsiwe
Publikováno v:
Vaccines, Vol 11, Iss 5, p 1000 (2023)
HIV is known to accumulate escape mutations in the gag gene in response to the immune response from cytotoxic T lymphocytes (CTLs). These mutations can occur within an individual as well as at a population level. The population of Botswana exhibits a
Externí odkaz:
https://doaj.org/article/cc5b46af2f8d4f3eb549ce98b15f493f
Autor:
Monkgomotsi J. Maseng, BSc, Leabaneng Tawe, PhD, Prisca K. Thami, PhD, Sikhulile Moyo, PhD, Ishmael Kasvosve, PhD, Vladimir Novitsky, PhD, Max Essex, PhD, Gianluca Russo, PhD, Simani Gaseitsiwe, PhD, Giacomo M. Paganotti, PhD, Jorddy Neves Cruz.
Publikováno v:
Medicine, Vol 101, Iss 17, p e29066 (2022)
Abstract. The two non-nucleoside reverse transcriptase inhibitors (NNRTIs), efavirenz (EFV) and nevirapine (NVP), are currently the core antiretroviral drugs for treatment of HIV in sub-Saharan Africa including Botswana. The drugs are metabolized by
Externí odkaz:
https://doaj.org/article/cfd885a8c22c47e2b69ba1852ada6668
Autor:
Leabaneng Tawe, Surbhi Grover, Nicola Zetola, Erle S. Robertson, Simani Gaseitsiwe, Sikhulile Moyo, Ishmael Kasvosve, Giacomo M. Paganotti, Mohan Narasimhamurthy
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Background: Epidemics of human immunodeficiency virus (HIV) and cervical cancer are interconnected. DNA hypermethylation of host genes' promoter in cervical lesions has also been recognized as a contributor to cervical cancer progression.Methods: For
Externí odkaz:
https://doaj.org/article/24c69684281e42c58a2ad7b3d2167cf1
Autor:
Leabaneng Tawe, Thato Motshoge, Pleasure Ramatlho, Naledi Mutukwa, Charles Waithaka Muthoga, Ghyslaine Bruna Djeunang Dongho, Axel Martinelli, Elias Peloewetse, Gianluca Russo, Isaac Kweku Quaye, Giacomo Maria Paganotti
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Identification of inter-individual variability for drug metabolism through cytochrome P450 2B6 (CYP2B6) enzyme is important for understanding the differences in clinical responses to malaria and HIV. This study evaluates the distribution of
Externí odkaz:
https://doaj.org/article/11b544b28c044d92bf3551d5f6492f3e
Autor:
Leabaneng Tawe, Surbhi Grover, Mohan Narasimhamurthy, Sikhulile Moyo, Simani Gaseitsiwe, Ishmael Kasvosve, Giacomo M. Paganotti
Publikováno v:
MethodsX, Vol 5, Iss , Pp 569-578 (2018)
Archived Formalin-Fixed Paraffin-Embedded (FFPE) tissue specimens can be a valuable source of human papillomavirus (HPV) nucleic acids for molecular biological analyses in retrospective studies. Although successful amplification with polymerase chain
Externí odkaz:
https://doaj.org/article/90ce6f715a1945cb8a0f4227b59c61e0