Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lea Wehrmann"'
Autor:
Frank Westermann, Stefan M. Pfister, Axel Benner, Thomas Höfer, Christoph Plass, Peter Schmezer, Alica Torkov, Emma Bell, David J. Duffy, Matthias Fischer, Lea Wehrmann, Martha Parzonka, Manuel Wiesenfarth, Carl Herrmann, Chunxuan Shao, Moritz Gartlgruber, Daniel Dreidax, Maral Saadati, Sebastian Bender, Kai-Oliver Henrich
Genes that significantly i) lost H3K27me3 coverage ii) lost DNA methylation iii) gained expression in Be(2)-C and IMR5-75 cells upon combination treatment with DAC and EPZ-6438
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694c03c20e3025df4dbad6de916299b9
https://doi.org/10.1158/0008-5472.22408902.v1
https://doi.org/10.1158/0008-5472.22408902.v1
Autor:
Frank Westermann, Stefan M. Pfister, Axel Benner, Thomas Höfer, Christoph Plass, Peter Schmezer, Alica Torkov, Emma Bell, David J. Duffy, Matthias Fischer, Lea Wehrmann, Martha Parzonka, Manuel Wiesenfarth, Carl Herrmann, Chunxuan Shao, Moritz Gartlgruber, Daniel Dreidax, Maral Saadati, Sebastian Bender, Kai-Oliver Henrich
Genes whose hypermethylation and downregulation are associated with high-risk disease (HyperDownHR) are repressed by MYCN in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f459a2e4a3cc7449196986953d9a5e5
https://doi.org/10.1158/0008-5472.22408911
https://doi.org/10.1158/0008-5472.22408911
Autor:
Frank Westermann, Stefan M. Pfister, Axel Benner, Thomas Höfer, Christoph Plass, Peter Schmezer, Alica Torkov, Emma Bell, David J. Duffy, Matthias Fischer, Lea Wehrmann, Martha Parzonka, Manuel Wiesenfarth, Carl Herrmann, Chunxuan Shao, Moritz Gartlgruber, Daniel Dreidax, Maral Saadati, Sebastian Bender, Kai-Oliver Henrich
The broad clinical spectrum of neuroblastoma ranges from spontaneous regression to rapid progression despite intensive multimodal therapy. This diversity is not fully explained by known genetic aberrations, suggesting the possibility of epigenetic in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327f0d8818b91704f53a375ebe5b0103
https://doi.org/10.1158/0008-5472.c.6507639.v1
https://doi.org/10.1158/0008-5472.c.6507639.v1
Autor:
Frank Westermann, Stefan M. Pfister, Axel Benner, Thomas Höfer, Christoph Plass, Peter Schmezer, Alica Torkov, Emma Bell, David J. Duffy, Matthias Fischer, Lea Wehrmann, Martha Parzonka, Manuel Wiesenfarth, Carl Herrmann, Chunxuan Shao, Moritz Gartlgruber, Daniel Dreidax, Maral Saadati, Sebastian Bender, Kai-Oliver Henrich
Genes significantly induced in Be(2)-C or IMR5-75 upon treatment with DAC, EPZ-6438 or a combination of both drugs (adjusted p-value
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5704bd3c148288ef5d1d29056f8f57
https://doi.org/10.1158/0008-5472.22408908
https://doi.org/10.1158/0008-5472.22408908
Autor:
Frank Westermann, Stefan M. Pfister, Axel Benner, Thomas Höfer, Christoph Plass, Peter Schmezer, Alica Torkov, Emma Bell, David J. Duffy, Matthias Fischer, Lea Wehrmann, Martha Parzonka, Manuel Wiesenfarth, Carl Herrmann, Chunxuan Shao, Moritz Gartlgruber, Daniel Dreidax, Maral Saadati, Sebastian Bender, Kai-Oliver Henrich
CpGs and genes associated with differential methylation and expression with respect to high-risk (HR) neuroblastoma disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320e424b0a056ad288ad3947f07a8a61
https://doi.org/10.1158/0008-5472.22408920
https://doi.org/10.1158/0008-5472.22408920
Autor:
Frank Westermann, Stefan M. Pfister, Axel Benner, Thomas Höfer, Christoph Plass, Peter Schmezer, Alica Torkov, Emma Bell, David J. Duffy, Matthias Fischer, Lea Wehrmann, Martha Parzonka, Manuel Wiesenfarth, Carl Herrmann, Chunxuan Shao, Moritz Gartlgruber, Daniel Dreidax, Maral Saadati, Sebastian Bender, Kai-Oliver Henrich
Description of additional methods and procedures used in the study. Also includes Supplementary References.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ec99b630e1853d6eb38c41bab7283f
https://doi.org/10.1158/0008-5472.22408926
https://doi.org/10.1158/0008-5472.22408926
Autor:
Frank Westermann, Stefan M. Pfister, Axel Benner, Thomas Höfer, Christoph Plass, Peter Schmezer, Alica Torkov, Emma Bell, David J. Duffy, Matthias Fischer, Lea Wehrmann, Martha Parzonka, Manuel Wiesenfarth, Carl Herrmann, Chunxuan Shao, Moritz Gartlgruber, Daniel Dreidax, Maral Saadati, Sebastian Bender, Kai-Oliver Henrich
Gene Ontology (GO) terms significantly enriched among genes whose hypermethylation and downregulation are associated with high-risk disease (HyperDownHR).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0261a640a0b32da525064d3cb2277121
https://doi.org/10.1158/0008-5472.22408914
https://doi.org/10.1158/0008-5472.22408914
Autor:
Frank Westermann, Stefan M. Pfister, Axel Benner, Thomas Höfer, Christoph Plass, Peter Schmezer, Alica Torkov, Emma Bell, David J. Duffy, Matthias Fischer, Lea Wehrmann, Martha Parzonka, Manuel Wiesenfarth, Carl Herrmann, Chunxuan Shao, Moritz Gartlgruber, Daniel Dreidax, Maral Saadati, Sebastian Bender, Kai-Oliver Henrich
Neuroblastoma-specific mutations in genes whose hypermethylation and downregulation are associated with high-risk neuroblastoma disease (HyperDownHR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e0ed9e7df165cb061a9b2e217a769ad
https://doi.org/10.1158/0008-5472.22408917.v1
https://doi.org/10.1158/0008-5472.22408917.v1
Autor:
Frank Westermann, Stefan M. Pfister, Axel Benner, Thomas Höfer, Christoph Plass, Peter Schmezer, Alica Torkov, Emma Bell, David J. Duffy, Matthias Fischer, Lea Wehrmann, Martha Parzonka, Manuel Wiesenfarth, Carl Herrmann, Chunxuan Shao, Moritz Gartlgruber, Daniel Dreidax, Maral Saadati, Sebastian Bender, Kai-Oliver Henrich
Genes whose hypermethylation and downregulation are associated with high-risk disease (HyperDownHR) are de-repressed upon combination treatment with epigenetically active drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b59ba2dd073c0a42524ca9cafabd457
https://doi.org/10.1158/0008-5472.22408899
https://doi.org/10.1158/0008-5472.22408899
Autor:
Frank Westermann, Stefan M. Pfister, Axel Benner, Thomas Höfer, Christoph Plass, Peter Schmezer, Alica Torkov, Emma Bell, David J. Duffy, Matthias Fischer, Lea Wehrmann, Martha Parzonka, Manuel Wiesenfarth, Carl Herrmann, Chunxuan Shao, Moritz Gartlgruber, Daniel Dreidax, Maral Saadati, Sebastian Bender, Kai-Oliver Henrich
Cox proportional hazards regression for overall survival (105 neuroblastomas)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b37f1a8164529d33f9cc0eca0abbab2
https://doi.org/10.1158/0008-5472.22408923
https://doi.org/10.1158/0008-5472.22408923