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Quantitative high-throughput measurement of gene expression with sub-zeptomole sensitivity by capillary electrophoresis

Autor: K. Leslie Powell, Howard D. Thames, Nikki Liburd, Lea Spyres, Stacey Arantes, Michael C. MacLeod, Ella Bedford, Earl F. Walborg, Mahmoud Rouabhia, C. Marcelo Aldaz, David L. Mitchell, Sally Gaddis

Publikováno v: Analytical Biochemistry. 345:284-295

Microarray technologies have provided the ability to monitor the expression of whole genomes rapidly. However, concerns persist with regard to quantitation and reproducibility, and the detection limits for individual genes in particular arrays are ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b47598489efc2544e83b5bb4176139c
https://doi.org/10.1016/j.ab.2005.07.022

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The high binding affinity of human ribosomal protein S3 to 7,8-dihydro-8-oxoguanine is abrogated by a single amino acid change

Autor: Lea Spyres, Mu Wang, Vijay Hegde, Walter A. Deutsch, I. Saira Mian

Publikováno v: DNA repair. 5(7)

Previous studies have shown that human ribosomal protein S3 (hS3) has a high apparent binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG) residues in DNA and interacts with the human base excision repair (BER) proteins OGG1 and APE/Ref-1. We used

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128f803b6d094457fd8c77f34f6511a2
https://pubmed.ncbi.nlm.nih.gov/16737853

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