Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lea Prokop"'
Autor:
Timo Burster, Jan Münch, Mike-Andrew Westhoff, David Palesch, Annika Meid, Christian Rainer Wirtz, Stefan Stevanovic, Marcin Sieńczyk, Lea Prokop, Marc-Eric Halatsch, Jutta Burkhardt, Michał Zimecki, Nicole Molenda, Johanna Elisabeth Wagner
Publikováno v:
Cancer Immunology, Immunotherapy. 65:283-291
To mount an adaptive immune response, MHC I molecules present antigenic peptides to CTLs. Transcriptional reduction of MHC I molecules is a strategy of immune evasion, which impairs the detection of infected or tumorous cells by CTLs. Natural killer
Autor:
Axel Schmidt, Stefan Gründer, Silke Kauferstein, Chih-Hsien Hung, Hubert Kalbacher, Cheng-Han Lee, Catharina Reimers, Yuemin Tian, Dietrich Mebs, Chih-Cheng Chen, Lea Prokop
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(17)
Acid-sensing ion channels (ASICs) are proton-gated Na+ channels that are expressed throughout the nervous system. ASICs have been implicated in several neuronal disorders, like ischemic stroke, neuronal inflammation, and pathological pain. Several to
Autor:
Sebastian P. Haen, Wichard Vogel, Hans-Georg Rammensee, Christoph Faul, Wolfgang Bethge, Nora Mirza, Daniel J. Kowalewski, Cécile Gouttefangeas, Lothar Kanz, Lea Prokop
Publikováno v:
Transplant immunology. 36
Background Heat shock proteins (HSP) are highly conserved immunogenic proteins serving as potent danger signals. They are upregulated under stress conditions like fever and hypoxia. Extracellular HSP are involved in antigen presentation, cytokine rel
Autor:
Lea Prokop, Harald Abele, Johannes T. Wessels, Oliver Pötz, Wilhelm K. Aicher, Mike Essl, Carolin Steinl, Gerd Klein, Stefan Stevanovic, Thomas D. Schreiber, Konstanze Geiger
Publikováno v:
Stem cells and development. 22(9)
Previous studies indicate that the release of proteases, including the gelatinase matrix metalloproteinase (MMP)-9, from mature granulocytes plays a crucial role in cytokine-induced hematopoietic stem and progenitor cell (HSPC) mobilization. However,
Publikováno v:
Cancer Immunology Research. 4:B057-B057
Peptide-based vaccines are a promising strategy for immunotherapy against cancer. Our group has characterized large numbers of HLA ligands from tumor cells; among them many that might be used for in vivo induction of tumor-specific immune responses.