Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lea Monteran"'
Autor:
Lea Monteran, Nour Ershaid, Hila Doron, Yael Zait, Ye’ela Scharff, Shahar Ben-Yosef, Camila Avivi, Iris Barshack, Amir Sonnenblick, Neta Erez
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Accumulating evidence suggest that chemotherapy could paradoxically promote cancer metastasis. Here the authors report that, in preclinical breast cancer models, adjuvant treatment with doxorubicin induces the formation of an immunosuppressive metast
Externí odkaz:
https://doaj.org/article/fe0fa38e48ba462a9fc114de90e35768
Autor:
Lea Monteran, Nour Ershaid, Idan Sabah, Ibrahim Fahoum, Yael Zait, Ophir Shani, Noam Cohen, Anat Eldar-Boock, Ronit Satchi-Fainaro, Neta Erez
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract The most common site of breast cancer metastasis is the bone, occurring in approximately 70% of patients with advanced disease. Bone metastasis is associated with severe morbidities and high mortality. Therefore, deeper understanding of the
Externí odkaz:
https://doaj.org/article/dbff80225c2243a0816be0111a06e98b
Autor:
Ophir Shani, Yael Raz, Lea Monteran, Ye'ela Scharff, Oshrat Levi-Galibov, Or Megides, Hila Shacham, Noam Cohen, Dana Silverbush, Camilla Avivi, Roded Sharan, Asaf Madi, Ruth Scherz-Shouval, Iris Barshack, Ilan Tsarfaty, Neta Erez
Publikováno v:
eLife, Vol 10 (2021)
Mortality from breast cancer is almost exclusively a result of tumor metastasis, and lungs are one of the main metastatic sites. Cancer-associated fibroblasts are prominent players in the microenvironment of breast cancer. However, their role in the
Externí odkaz:
https://doaj.org/article/c920622612bb4137aabc24c393bb62d6
Autor:
Nour Ershaid, Yoray Sharon, Hila Doron, Yael Raz, Ophir Shani, Noam Cohen, Lea Monteran, Leonor Leider-Trejo, Amir Ben-Shmuel, Muhammad Yassin, Motti Gerlic, Adit Ben-Baruch, Metsada Pasmanik-Chor, Roni Apte, Neta Erez
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Cancer associated fibroblasts (CAFs) are known to promote pro-tumorigenic inflammation. Here, the authors show that CAFs sense tissue damage and activate NLRP3 inflammasome and pro-inflammatory IL-1β secretion, and CAF-derived inflammasome signallin
Externí odkaz:
https://doaj.org/article/e17f97fa635942b78830a281b1c5e026
Autor:
Hila Doron, Malak Amer, Nour Ershaid, Raquel Blazquez, Ophir Shani, Tzlil Gener Lahav, Noam Cohen, Omer Adler, Zahi Hakim, Sabina Pozzi, Anna Scomparin, Jonathan Cohen, Muhammad Yassin, Lea Monteran, Rachel Grossman, Galia Tsarfaty, Chen Luxenburg, Ronit Satchi-Fainaro, Tobias Pukrop, Neta Erez
Publikováno v:
Cell Reports, Vol 28, Iss 7, Pp 1785-1798.e6 (2019)
Summary: Melanoma is the deadliest skin cancer due to its high rate of metastasis, frequently to the brain. Brain metastases are incurable; therefore, understanding melanoma brain metastasis is of great clinical importance. We used a mouse model of s
Externí odkaz:
https://doaj.org/article/02f588d3f2414c569cfd2b807ec8f3e3
Autor:
Lea Monteran, Neta Erez
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Cancer-associated fibroblasts (CAFs) are prominent components of the microenvironment in most types of solid tumors, and were shown to facilitate cancer progression by supporting tumor cell growth, extracellular matrix remodeling, promoting angiogene
Externí odkaz:
https://doaj.org/article/c7ed10311a18485b9a2c4de48c8ea39e
Autor:
Neta Erez, Iris Barshack, Camila Avivi, Galia Tsarfaty, Yael Raz, Noam Cohen, Dor Lavie, Lea Monteran, Tatiana Vorobyov, Ophir Shani
Figure S4 shows that IL-33 is essential for eosinophil recruitment to the metastatic lung.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0fe59aef738ca2096e3f955f72fa0d6
https://doi.org/10.1158/0008-5472.22425925.v1
https://doi.org/10.1158/0008-5472.22425925.v1
Autor:
Neta Erez, Iris Barshack, Camila Avivi, Galia Tsarfaty, Yael Raz, Noam Cohen, Dor Lavie, Lea Monteran, Tatiana Vorobyov, Ophir Shani
Lungs are one of the main sites of breast cancer metastasis. The metastatic microenvironment is essential to facilitate growth of disseminated tumor cells. Cancer-associated fibroblasts (CAF) are prominent players in the microenvironment of breast ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7f6fae71c9adc4be6c796208f62d38
https://doi.org/10.1158/0008-5472.c.6512185
https://doi.org/10.1158/0008-5472.c.6512185
Autor:
Omer Adler, Yael Zait, Noam Cohen, Raquel Blazquez, Hila Doron, Lea Monteran, Yeela Scharff, Tamar Shami, Dhanashree Mundhe, Gunther Glehr, Andrew A. Kanner, Suzana Horn, Vered Yahalom, Sebastian Haferkamp, James A. Hutchinson, Annalen Bleckmann, Limor Nahary, Itai Benhar, Shlomit Yust Katz, Tobias Pukrop, Neta Erez
Brain metastasis still encompass very grim prognosis and therefore understanding the underlying mechanisms is an urgent need toward developing better therapeutic strategies. We uncover the intricate interactions between recruited innate immune cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92bb1f5a6cad16d83d0a96ec229042b8
https://publica.fraunhofer.de/handle/publica/439566
https://publica.fraunhofer.de/handle/publica/439566
Autor:
Lea Monteran, Neta Erez
Publikováno v:
Trends in cancer. 9(1)
New findings (Krishnamurty et al.) implicate a subset of cancer-associated fibroblasts (CAFs) that express leucine-rich repeat containing 15 (LRRC15) in promoting tumor growth in pancreatic adenocarcinoma (PDAC), by suppressing the antitumor immunity