Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Lea M Starita"'
Autor:
James P Hughes, Helen Y Chu, Lea M Starita, Peter D Han, Caitlin R Wolf, Geoffrey S Gottlieb, Marco Carone, Zachary Acker, Ana A Weil, Julia Catherine Bennett, Jessica O’Hanlon, Devon McDonald, Tessa Wright, Kyle G Luiten, Lani Regelbrugge, Kathryn M McCaffrey, Brian Pfau
Publikováno v:
BMJ Open, Vol 14, Iss 6 (2024)
Objective We aimed to evaluate the feasibility and utility of an unsupervised testing mechanism, in which participants pick up a swab kit, self-test (unsupervised) and return the kit to an on-campus drop box, as compared with supervised self-testing
Externí odkaz:
https://doaj.org/article/60a395f9b13b4ddfa518d2fcce6a20e5
Autor:
Miguel I Paredes, Amanda C Perofsky, Lauren Frisbie, Louise H Moncla, Pavitra Roychoudhury, Hong Xie, Shah A Mohamed Bakhash, Kevin Kong, Isabel Arnould, Tien V Nguyen, Seffir T Wendm, Pooneh Hajian, Sean Ellis, Patrick C Mathias, Alexander L Greninger, Lea M Starita, Chris D Frazar, Erica Ryke, Weizhi Zhong, Luis Gamboa, Machiko Threlkeld, Jover Lee, Jeremy Stone, Evan McDermot, Melissa Truong, Jay Shendure, Hanna N Oltean, Cécile Viboud, Helen Chu, Nicola F Müller, Trevor Bedford
Publikováno v:
PLoS Pathogens, Vol 20, Iss 3, p e1012117 (2024)
SARS-CoV-2 transmission is largely driven by heterogeneous dynamics at a local scale, leaving local health departments to design interventions with limited information. We analyzed SARS-CoV-2 genomes sampled between February 2020 and March 2022 joint
Externí odkaz:
https://doaj.org/article/969775afc55a4a1ba6bff822d4c59f3f
Autor:
Mariame Diabate, Muhtadi M Islam, Gregory Nagy, Tapahsama Banerjee, Shruti Dhar, Nahum Smith, Aleksandra I Adamovich, Lea M Starita, Jeffrey D Parvin
Publikováno v:
PLoS Genetics, Vol 19, Iss 8, p e1010739 (2023)
Single nucleotide variants are the most frequent type of sequence changes detected in the genome and these are frequently variants of uncertain significance (VUS). VUS are changes in DNA for which disease risk association is unknown. Thus, methods th
Externí odkaz:
https://doaj.org/article/5e5fff7cb983421cac075a75fd103b1c
Autor:
Gregory Nagy, Mariame Diabate, Tapahsama Banerjee, Aleksandra I Adamovich, Nahum Smith, Hyeongseon Jeon, Shruti Dhar, Wenfang Liu, Katherine Burgess, Dongjun Chung, Lea M Starita, Jeffrey D Parvin
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0293422 (2023)
Delineating functionally normal variants from functionally abnormal variants in tumor suppressor proteins is critical for cancer surveillance, prognosis, and treatment options. BRCA1 is a protein that has many variants of uncertain significance which
Externí odkaz:
https://doaj.org/article/fbe58a277f384eba8372bc3c726395ab
Autor:
Atanas Radkov, Anne L Sapiro, Sebastian Flores, Corey Henderson, Hayden Saunders, Rachel Kim, Steven Massa, Samuel Thompson, Chase Mateusiak, Jacob Biboy, Ziyi Zhao, Lea M Starita, William L Hatleberg, Waldemar Vollmer, Alistair B Russell, Jean-Pierre Simorre, Spencer Anthony-Cahill, Peter Brzovic, Beth Hayes, Seemay Chou
Publikováno v:
eLife, Vol 11 (2022)
Members of the bacterial T6SS amidase effector (Tae) superfamily of toxins are delivered between competing bacteria to degrade cell wall peptidoglycan. Although Taes share a common substrate, they exhibit distinct antimicrobial potency across differe
Externí odkaz:
https://doaj.org/article/e8b6e88e62cc4ba1b7e72be730157666
Autor:
Rachel E Geyer, Jack Henry Kotnik, Victoria Lyon, Elisabeth Brandstetter, Monica Zigman Suchsland, Peter D Han, Chelsey Graham, Misja Ilcisin, Ashley E Kim, Helen Y Chu, Deborah A Nickerson, Lea M Starita, Trevor Bedford, Barry Lutz, Matthew J Thompson
Publikováno v:
JMIR Public Health and Surveillance, Vol 8, Iss 2, p e28268 (2022)
BackgroundRapid diagnostic tests (RDTs) for influenza used by individuals at home could potentially expand access to testing and reduce the impact of influenza on health systems. Improving access to testing could lead to earlier diagnosis following s
Externí odkaz:
https://doaj.org/article/d6aeff5866aa4eec992ec25175f929cb
Autor:
Kira Newman, Helen Y Chu, Michael Boeckh, Janet A Englund, Michael Famulare, Lea M Starita, Elisabeth Brandstetter, Chris D Frazer, Peter D Han, Reena K Gulati, James Hadfield, Anahita Kiavand, Louise E Kimball, Kirsten Lacombe, Thomas R Sibley, Jennifer K Logue, Victoria Rachel Lyon, Caitlin R Wolf, Jay Shendure, Trevor Bedford
Publikováno v:
BMJ Open, Vol 10, Iss 10 (2020)
Introduction Influenza epidemics and pandemics cause significant morbidity and mortality. An effective response to a potential pandemic requires the infrastructure to rapidly detect, characterise, and potentially contain new and emerging influenza st
Externí odkaz:
https://doaj.org/article/9354581cd4824a23807adf4d7d2148c7
Autor:
Eric J. Chow, Amanda M. Casto, Reigran Sampoleo, Margaret G. Mills, Peter D. Han, Hong Xie, Brian Pfau, Tien V. Nguyen, Jaydee Sereewit, Julia H. Rogers, Sarah N. Cox, Melissa A. Rolfes, Constance Ogokeh, Emily Mosites, Timothy M. Uyeki, Alexander L. Greninger, James P. Hughes, M. Mia Shim, Nancy Sugg, Jeffrey S. Duchin, Lea M. Starita, Janet A. Englund, Pavitra Roychoudhury, Helen Y. Chu
Publikováno v:
Emerging Infectious Diseases. 28:2343-2347
To determine the epidemiology of human parainfluenza virus in homeless shelters during the COVID-19 pandemic, we analyzed data and sequences from respiratory specimens collected in 23 shelters in Washington, USA, during 2019-2021. Two clusters in chi
Autor:
Eric J Chow, Amanda M Casto, Pavitra Roychoudhury, Peter D Han, Hong Xie, Brian Pfau, Tien V Nguyen, Jaydee Sereewit, Julia H Rogers, Sarah N Cox, Caitlin R Wolf, Melissa A Rolfes, Emily Mosites, Timothy M Uyeki, Alexander L Greninger, James P Hughes, M Mia Shim, Nancy Sugg, Jeffrey S Duchin, Lea M Starita, Janet A Englund, Helen Y Chu
Publikováno v:
The Journal of Infectious Diseases. 226:S304-S314
Background Rhinovirus (RV) is a common cause of respiratory illness in all people, including those experiencing homelessness. RV epidemiology in homeless shelters is unknown. Methods We analyzed data from a cross-sectional homeless shelter study in K
The breast and ovarian cancer specific tumor suppressor BRCA1, bound to BARD1, has multiple functions aimed at maintaining genomic stability in the cell. We have shown earlier that the BRCA1/BARD1 E3 ubiquitin ligase activity regulates centrosome-dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145c9b9d498e14fd4c03791bcd39a684
https://doi.org/10.1158/0008-5472.c.6494777
https://doi.org/10.1158/0008-5472.c.6494777