Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lea M D, Delbridge"'
Autor:
Ayeshah A. Rosdah, Belinda M. Abbott, Christopher G. Langendorf, Yali Deng, Jia Q. Truong, Helen M. M. Waddell, Naomi X. Y. Ling, William J. Smiles, Lea M. D. Delbridge, Guei-Sheung Liu, Jonathan S. Oakhill, Shiang Y. Lim, Jessica K. Holien
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Mitochondrial dynamin-related protein 1 (Drp1) is a large GTPase regulator of mitochondrial dynamics and is known to play an important role in numerous pathophysiological processes. Despite being the most widely used Drp1 inhibitor, the spec
Externí odkaz:
https://doaj.org/article/81d43f7ed5984ba3b02b0644c4d9b73f
Autor:
Sanela Dozic, Erin J. Howden, James R. Bell, Kimberley M. Mellor, Lea M. D. Delbridge, Kate L. Weeks
Publikováno v:
Cells, Vol 12, Iss 9, p 1312 (2023)
Anthracyclines such as doxorubicin are widely used chemotherapy drugs. A common side effect of anthracycline therapy is cardiotoxicity, which can compromise heart function and lead to dilated cardiomyopathy and heart failure. Dexrazoxane and heart fa
Externí odkaz:
https://doaj.org/article/06a36267e1694e0bbe437a450007a528
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The global burden of ischemic heart disease is burgeoning for both men and women. Although advances have been made, the need for new sex-specific therapies targeting key differences in cardiovascular disease outcomes in men and women remains. Mineral
Externí odkaz:
https://doaj.org/article/2ca3a299e4684040a85af5ca9f50011c
Autor:
Lorna J. Daniels, Marco Annandale, Parisa Koutsifeli, Xun Li, Carol T. Bussey, Isabelle van Hout, Richard W. Bunton, Philip J. Davis, Sean Coffey, Rajesh Katare, Regis R. Lamberts, Lea M. D. Delbridge, Kimberley M. Mellor
Publikováno v:
Nutrition & Diabetes, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Diabetes is associated with cardiac metabolic disturbances and increased heart failure risk. Plasma fructose levels are elevated in diabetic patients. A direct role for fructose involvement in diabetic heart pathology has not been investigat
Externí odkaz:
https://doaj.org/article/71cc5f2d30f7420783f9df21ea649854
Autor:
Shouryadipta Ghosh, Kenneth Tran, Lea M D Delbridge, Anthony J R Hickey, Eric Hanssen, Edmund J Crampin, Vijay Rajagopal
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 12, p e1006640 (2018)
Recent electron microscopy data have revealed that cardiac mitochondria are not arranged in crystalline columns but are organised with several mitochondria aggregated into columns of varying sizes spanning the cell cross-section. This raises the ques
Externí odkaz:
https://doaj.org/article/685ae461511743d199a4935553e960f2
Autor:
Ayeshah A. Rosdah, Belinda M. Abbott, Christopher G. Langendorf, Yali Deng, Jia Q. Truong, Helen M. M. Waddell, Naomi X. Y. Ling, William J. Smiles, Lea M. D. Delbridge, Guei-Sheung Liu, Jonathan S. Oakhill, Shiang Y. Lim, Jessica K. Holien
Mitochondrial dynamin-related protein 1 (Drp1) is a large GTPase regulator of mitochondrial dynamics and is known to play an important role in numerous pathophysiological processes. Despite being the most widely used Drp1 inhibitor, the specificity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a9619ddb93dfb9fcff13ce685136a5
Autor:
Claire L. Curl, Vennetia R. Danes, James R. Bell, Antonia J. A. Raaijmakers, Wendy T. K. Ip, Chanchal Chandramouli, Tristan W. Harding, Enzo R. Porrello, Jeffrey R. Erickson, Fadi J. Charchar, Andrew R. Kompa, Amanda J. Edgley, David J. Crossman, Christian Soeller, Kimberley M. Mellor, Jonathan M. Kalman, Stephen B. Harrap, Lea M. D. Delbridge
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 11 (2018)
BackgroundAmong the growing numbers of patients with heart failure, up to one half have heart failure with preserved ejection fraction (HFpEF). The lack of effective treatments for HFpEF is a substantial and escalating unmet clinical need—and the l
Externí odkaz:
https://doaj.org/article/1d494628ead14a7dbee011a799b45a35
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 323(4)
Publikováno v:
World Family Medicine Journal/Middle East Journal of Family Medicine. 17:42-46
Publikováno v:
World Family Medicine Journal/Middle East Journal of Family Medicine. 17:47-51