Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lea Kyhälä"'
Autor:
Lea Kyhälä, Panu Mentula, Leena Kylänpää, Eeva Moilanen, Pauli Puolakkainen, Ville Pettilä, Heikki Repo
Publikováno v:
International Journal of Inflammation, Vol 2012 (2012)
The study aimed to determine the effect of the activated protein C on the course of systemic inflammation in the APCAP (activated protein C in acute pancreatitis) trial where we randomized 32 patients with severe acute pancreatitis to receive either
Externí odkaz:
https://doaj.org/article/d8375a746f3a4fa091065bf4199fb72c
Autor:
Jari Petäjä, Esko Kemppainen, Heikki Repo, Pauli Puolakkainen, Ville Pettilä, Minna Tallgren, Leena Kylänpää, Harri Mustonen, Outi Lindström, Lea Kyhälä
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 76:10-16
Activated protein C (APC), an endogenous anticoagulant, has antithrombotic, fibrinolytic and anti-inflammatory properties. We recently conducted a controlled study (APCAP, activated protein C in severe acute pancreatitis) of APC treatment of patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b1b8807af535987c3eb80a94136d95
https://doi.org/10.3109/00365513.2015.1084041
https://doi.org/10.3109/00365513.2015.1084041
Autor:
Mikael Maksimow, Marko Salmi, Panu Mentula, Heikki Repo, Kristiina Aalto, Mari S. Lehti, Leena Kylänpää, Lea Kyhälä, Sirpa Jalkanen, Kati Elima, Gennady G. Yegutkin, Anne Nieminen, Pauli Puolakkainen
Publikováno v:
Critical Care Medicine. 42:2556-2564
Objective:New biomarkers are needed to better predict the severity of acute pancreatitis. CD73/ecto-5’-nucleotidase is an enzyme that generates adenosine, which dampens inflammation and improves vascular barrier function in several disease models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2649e3d3d76f2664139fd946890725bd
https://doi.org/10.1097/ccm.0000000000000550
https://doi.org/10.1097/ccm.0000000000000550
Autor:
Eeva Moilanen, Heikki Repo, Lea Kyhälä, Leena Kylänpää, Panu Mentula, Ville Pettilä, Pauli Puolakkainen
Publikováno v:
International Journal of Inflammation, Vol 2012 (2012)
International Journal of Inflammation
International Journal of Inflammation
The study aimed to determine the effect of the activated protein C on the course of systemic inflammation in the APCAP (activated protein C in acute pancreatitis) trial where we randomized 32 patients with severe acute pancreatitis to receive either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b3f4b08d4545078be2293e642f09f6
https://doi.org/10.1155/2012/712739
https://doi.org/10.1155/2012/712739
Autor:
Marja-Leena Kylänpää, Esko Kemppainen, Pauli Puolakkainen, Harri Mustonen, Saara Aittomäki, Jani Oiva, Sanna Siitonen, Tiina Alanärä, Heikki Repo, Lea Kyhälä
Publikováno v:
Critical care medicine. 38(8)
To outline signaling profiles and transmigration capacity of monocytes of patients with severe acute pancreatitis.Prospective study.University hospital intensive care unit.Thirteen patients with severe acute pancreatitis. All patients had organ dysfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4cd4dd710ab0aef9d7c4bcc8a395cc
https://pubmed.ncbi.nlm.nih.gov/20647806
https://pubmed.ncbi.nlm.nih.gov/20647806
Autor:
Pauli Puolakkainen, Minna Tallgren, Ville Pettilä, Esko Kemppainen, Marja-Leena Kylänpää, Antti T. Markkola, Ari Leppäniemi, Heikki Repo, Lea Kyhälä
Publikováno v:
Critical Care
Introduction: Previous human studies have shown low activity of protein C (APC) in severe acute pancreatitis (SAP). This, together with the findings in animal models, suggests that activated protein C (APC) may protect against pancreatic injury and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6ccc96909c5841657837558001fee9
https://pubmed.ncbi.nlm.nih.gov/20707935
https://pubmed.ncbi.nlm.nih.gov/20707935
Autor:
Mikael Maksimow, Lea Kyhälä, Leena Kylänpää, Panu Mentula, Gennady G. Yegutkin, Heikki Repo, Marko Salmi
Publikováno v:
Critical Care Medicine. 43:e260
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3788ff5d679b6a3f1db2fadadf0289
https://doi.org/10.1097/ccm.0000000000000977
https://doi.org/10.1097/ccm.0000000000000977
Autor:
Mikael Maksimow, Anne Nieminen, Pauli Puolakkainen, Panu Mentula, Lea Kyhälä, Heikki Repo, Esko Kemppainen, Marko Salmi, Leena Kylänpää
Publikováno v:
Pancreatology. 13:e60
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcf100efda7673b2be5116b256e10820
https://doi.org/10.1016/j.pan.2012.12.266
https://doi.org/10.1016/j.pan.2012.12.266
Autor:
Marja-Leena Kylänpää, Lea Kyhälä, Esko Kemppainen, Sanna Siitonen, Pauli Puolakkainen, Harri Mustonen, Krista Kuuliala, Jani Oiva, Heikki Repo
Publikováno v:
Critical Care
Introduction Severe acute pancreatitis is associated with systemic inflammation, compensatory immune suppression, secondary infections, vital organ dysfunction, and death. Our study purpose was to delineate signaling profiles of circulating lymphocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743d30b5a1e47afc0cef60caa004eebf
http://europepmc.org/articles/PMC3220021
http://europepmc.org/articles/PMC3220021
Autor:
Pauli Puolakkainen, Panu Mentula, Leena Kylänpää, Esko Kemppainen, Heikki Repo, Anne Nieminen, Lea Kyhälä, Mikael Maksimow, Marko Salmi
Publikováno v:
Critical Care
Introduction Severe acute pancreatitis (AP) is associated with high morbidity and mortality. Early prediction of severe AP is needed to improve patient outcomes. The aim of the present study was to find novel cytokines or combinations of cytokines th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7f2f893231c767ba2f1a6098da6378