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Akademický článek

Author Correction: Enzymatic production of all fourteen partially acetylated chitosan tetramers using different chitin deacetylases acting in forward or reverse mode

Autor: Lea Hembach, Stefan Cord-Landwehr, Bruno M. Moerschbacher

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-2 (2022)

Externí odkaz: https://doaj.org/article/a2d9b17d1d7942d48187ae8f5eebd52f

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Unique subsite specificity and potential natural function of a chitosan deacetylase from the human pathogen Cryptococcus neoformans

Autor: Martin Bonin, Lea Hembach, Bruno M. Moerschbacher, Christian Gorzelanny

Publikováno v: Proceedings of the National Academy of Sciences. 117:3551-3559

Cryptococcus neoformans is an opportunistic fungal pathogen that infects ∼280,000 people every year, causing >180,000 deaths. The human immune system recognizes chitin as one of the major cell-wall components of invading fungi, but C. neoformans ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df80ce90b3eda8a079167d805a713c33
https://doi.org/10.1073/pnas.1915798117

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In silico and in vitro analysis of an Aspergillus niger chitin deacetylase to decipher its subsite sugar preferences

Autor: Gurvan Michel, Stefan Cord-Landwehr, Lisanne Hameleers, Bruno M. Moerschbacher, Lea Hembach, Martin Bonin, Thomas Roret

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, pp.101129. ⟨10.1016/j.jbc.2021.101129⟩
The Journal of Biological Chemistry

International audience; Chitin deacetylases (CDAs) are found in many different organisms ranging from marine bacteria to fungi and insects. These enzymes catalyze the removal of acetyl groups from chitinous substrates generating various chitosans, li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e5a8156c2839ae9f758d459d1334dd
https://hal.sorbonne-universite.fr/hal-03354312

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Unique subsite specificity and potential natural function of a chitosan deacetylase from the human pathogen

Autor: Lea, Hembach, Martin, Bonin, Christian, Gorzelanny, Bruno M, Moerschbacher

Publikováno v: Proc Natl Acad Sci U S A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::87e0cdfc4951a713716086e67c3c85b1
https://pubmed.ncbi.nlm.nih.gov/32015121

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A single intracellular protein governs the critical transition from an individual to a coordinated population response during quorum sensing: Origins of primordial language

Autor: Lea Hembach, C. Vila-Sanjurjo, Francisco M. Goycoolea, Carmen Remuñán-López, Antón Vila-Sanjurjo, Christoph Engwer, Xiaofei Qin, Tania Verdía-Cotelo

Quorum sensing (QS) explains a type of bacterial cell-cell communication mediated by exocellular compounds that act as autoinducers (AIs). As such, QS can be considered the most primordial form of language. QS has profound implications for the contro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a5ee5100d9efea20e2beee883325d1

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