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A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice

Autor: Lundbäck, Peter, Lea, Jonathan D., Sowinska, Agnieszka, Ottosson, Lars, Fürst, Camilla Melin, Steen, Johanna, Aulin, Cecilia, Clarke, Joanna I., Kipar, Anja, Klevenvall, Lena, Yang, Huan, Palmblad, Karin, Park, B. Kevin, Tracey, Kevin J., Blom, Anna M., Andersson, Ulf, Antoine, Daniel J., Erlandsson Harris, Helena

Publikováno v: Hepatology
Lundbäck, P, Lea, J D, Sowinska, A, Ottosson, L, Fürst, C M, Steen, J, Aulin, C, Clarke, J I, Kipar, A, Klevenvall, L, Yang, H, Palmblad, K, Park, B K, Tracey, K J, Blom, A M, Andersson, U, Antoine, D J & Erlandsson Harris, H 2016, ' A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice ', Hepatology, vol. 64, no. 5, pp. 1699-1710 . https://doi.org/10.1002/hep.28736
Hepatology (Baltimore, Md.)

Acetaminophen (APAP) overdoses are of major clinical concern. Growing evidence underlines a pathogenic contribution of sterile postinjury inflammation in APAP-induced acute liver injury (APAP-ALI) and justifies development of anti-inflammatory therap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0688d314b057ad5646a8b82a7c04e7c4
http://livrepository.liverpool.ac.uk/3004681/1/s1-ln22936533-975314624-1939656818Hwf-1518847911IdV-119416326822936533PDF_HI0001.pdf

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