Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lea, Hänschke"'
Autor:
Ben D. McNally, Dean F. Ashley, Lea Hänschke, Hélène N. Daou, Nicole T. Watt, Steven A. Murfitt, Amanda D. V. MacCannell, Anna Whitehead, T. Scott Bowen, Francis W. B. Sanders, Michele Vacca, Klaus K. Witte, Graeme R. Davies, Reinhard Bauer, Julian L. Griffin, Lee D. Roberts
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Endoplasmic Reticulum stress induces cell non-autonomous Unfolded Protein Response (UPR) activation. Here the authors show that long-chain ceramides are secreted from muscle cells in extracellular vesicles and induce cell non-autonomous UPR activatio
Externí odkaz:
https://doaj.org/article/e431ba3360bc41d78c30c04a825835be
Autor:
Lea Hänschke, Christoph Heier, Santiago José Maya Palacios, Huseyin Erdem Özek, Christoph Thiele, Reinhard Bauer, Ronald P. Kühnlein, Margret H. Bülow
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
The human LIPA gene encodes for the enzyme lysosomal acid lipase, which hydrolyzes cholesteryl ester and triacylglycerol. Lysosomal acid lipase deficiency results in Wolman disease and cholesteryl ester storage disease. The Drosophila genome encodes
Externí odkaz:
https://doaj.org/article/153473ccf6b24bffb4a99506d3235db3
Autor:
Julia Sellin, Christian Wingen, Dominic Gosejacob, Deniz Senyilmaz, Lea Hänschke, Sven Büttner, Katharina Meyer, Daniele Bano, Pierluigi Nicotera, Aurelio A Teleman, Margret H Bülow
Publikováno v:
PLoS Biology, Vol 16, Iss 6, p e2004893 (2018)
Mutations in peroxin (PEX) genes lead to loss of peroxisomes, resulting in the formation of peroxisomal biogenesis disorders (PBDs) and early lethality. Studying PBDs and their animal models has greatly contributed to our current knowledge about pero
Externí odkaz:
https://doaj.org/article/d109238ba3e44af1bae822ca6ac874e9
Autor:
Ben D, McNally, Dean F, Ashley, Lea, Hänschke, Hélène N, Daou, Nicole T, Watt, Steven A, Murfitt, Amanda D V, MacCannell, Anna, Whitehead, T Scott, Bowen, Francis W B, Sanders, Michele, Vacca, Klaus K, Witte, Graeme R, Davies, Reinhard, Bauer, Julian L, Griffin, Lee D, Roberts
Publikováno v:
Nature communications. 13(1)
The endoplasmic reticulum (ER) regulates cellular protein and lipid biosynthesis. ER dysfunction leads to protein misfolding and the unfolded protein response (UPR), which limits protein synthesis to prevent cytotoxicity. Chronic ER stress in skeleta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::136343b99869ea2fdc2bd8946d79edab
https://pubmed.ncbi.nlm.nih.gov/35365625
https://pubmed.ncbi.nlm.nih.gov/35365625
Autor:
Deniz Senyilmaz, Daniele Bano, Pierluigi Nicotera, Katharina Meyer, Sven Büttner, Christian Wingen, Lea Hänschke, Aurelio A. Teleman, Julia Sellin, Margret H. Bülow, Dominic Gosejacob
Publikováno v:
PLoS biology 16(6), e2004893 (2018). doi:10.1371/journal.pbio.2004893
PLoS Biology, Vol 16, Iss 6, p e2004893 (2018)
PLoS Biology
PLoS Biology, Vol 16, Iss 6, p e2004893 (2018)
PLoS Biology
Mutations in peroxin (PEX) genes lead to loss of peroxisomes, resulting in the formation of peroxisomal biogenesis disorders (PBDs) and early lethality. Studying PBDs and their animal models has greatly contributed to our current knowledge about pero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd05bf3d613ad17fc77bd4cac44e01ad
https://doi.org/10.1371/journal.pbio.2004893
https://doi.org/10.1371/journal.pbio.2004893