Zobrazeno 1 - 6
of 6
pro vyhledávání: '"LeYe Yan"'
Publikováno v:
Cancer Reports, Vol 6, Iss 10, Pp n/a-n/a (2023)
Abstract Background Patients with combined hepatocellular‐cholangiocarcinoma (cHCC‐CCA) have limited treatment options and poor prognosis. Tumor‐associated macrophages (TAMs) are the most abundant infiltrating immune cells in the tumor microenv
Externí odkaz:
https://doaj.org/article/a14ac3eeeaf74e798b25e2b3d4841d41
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Increased tryptophan (Trp) metabolism by indoleamine 2,3-dioxygenase (IDO)/tryptophan 2,3-dioxygenase (TDO) represents one of the most studied pathways for immunosuppression in tumor tissues. However, the pro-tumor effects induced
Externí odkaz:
https://doaj.org/article/9e9987c6d5ae40aca206b996510eb140
Autor:
Junqing Lin, Leye Yan, Xiaolong Wang, Zhengzhong Wu, Kun Ke, Xin Lin, Ning Huang, Weizhu Yang
Publikováno v:
Advances in Polymer Technology, Vol 2022 (2022)
Purpose. We aimed to examine the effects of 125I seeds on the gene expression of Bcl-2, Bax, and PI3K/Akt pathway components in cholangiocarcinoma cells. Methods. In vitro, human cholangiocarcinoma RBE cells were treated with 125I seeds (0.39 mCi or
Externí odkaz:
https://doaj.org/article/49d217b766b243bd9055d79cc0a79e43
Autor:
TianCheng Wang, MinZhao Lin, JunJie Mao, LiRong Tian, HaiRun Gan, XinYan Hu, LeYe Yan, HaoYu Long, JianXun Cai, XiaoDi Zheng, YuDong Xiao, Dan Li, XinTao Shuai, PengFei Pang
Publikováno v:
ACS applied materialsinterfaces.
Immune checkpoint blockade (ICB) utilizing programmed death ligand-1 (PD-L1) antibody is a promising treatment strategy in solid tumors. However, in fact, more than half of hepatocellular carcinoma (HCC) patients are unresponsive to PD-L1-based ICB t
Transthyretin in promoting cholangiocarcinoma cell invasion by macrophages in tumor microenvironment
Purpose: To investigate the involvement of transthyretin (TTR) in promoting cholangiocarcinoma (CCA) cell invasion by macrophages and to elucidate the role of TTR in cholangiocarcinoma migration and invasion.Methods: Immunohistochemical detection of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c69edc9ba921e8ce4c2d8311b0c965f7
https://doi.org/10.21203/rs.3.rs-1493940/v1
https://doi.org/10.21203/rs.3.rs-1493940/v1
Publikováno v:
Translational cancer research. 11(1)
The majority of patients with hepatocellular carcinoma (HCC) are diagnosed in an advanced stage. Although sorafenib is recommended as the standard treatment for advanced HCC, its efficacy is limited. In some studies, hepatic arterial infusion chemoth