Sequencing by avidity enables high accuracy with low reagent consumption.

Autor: Arslan S; Element Biosciences, San Diego, CA, USA., Garcia FJ; Element Biosciences, San Diego, CA, USA., Guo M; Element Biosciences, San Diego, CA, USA., Kellinger MW; Element Biosciences, San Diego, CA, USA., Kruglyak S; Element Biosciences, San Diego, CA, USA., LeVieux JA; Element Biosciences, San Diego, CA, USA., Mah AH; Element Biosciences, San Diego, CA, USA., Wang H; Element Biosciences, San Diego, CA, USA., Zhao J; Element Biosciences, San Diego, CA, USA., Zhou C; Element Biosciences, San Diego, CA, USA., Altomare A; Element Biosciences, San Diego, CA, USA., Bailey J; Element Biosciences, San Diego, CA, USA., Byrne MB; Element Biosciences, San Diego, CA, USA., Chang C; Element Biosciences, San Diego, CA, USA., Chen SX; Element Biosciences, San Diego, CA, USA., Cho B; Element Biosciences, San Diego, CA, USA., Dennler CN; Element Biosciences, San Diego, CA, USA., Dien VT; Element Biosciences, San Diego, CA, USA., Fuller D; Element Biosciences, San Diego, CA, USA., Kelley R; Element Biosciences, San Diego, CA, USA., Khandan O; Element Biosciences, San Diego, CA, USA., Klein MG; Element Biosciences, San Diego, CA, USA., Kim M; Element Biosciences, San Diego, CA, USA., Lajoie BR; Element Biosciences, San Diego, CA, USA., Lin B; Element Biosciences, San Diego, CA, USA., Liu Y; Element Biosciences, San Diego, CA, USA., Lopez T; Element Biosciences, San Diego, CA, USA., Mains PT; Element Biosciences, San Diego, CA, USA., Price AD; Element Biosciences, San Diego, CA, USA., Robertson SR; Element Biosciences, San Diego, CA, USA., Taylor-Weiner H; Element Biosciences, San Diego, CA, USA., Tippana R; Element Biosciences, San Diego, CA, USA., Tomaney AB; Element Biosciences, San Diego, CA, USA., Zhang S; Element Biosciences, San Diego, CA, USA., Abtahi M; Element Biosciences, San Diego, CA, USA., Ambroso MR; Element Biosciences, San Diego, CA, USA., Bajari R; Element Biosciences, San Diego, CA, USA., Bellizzi AM; Element Biosciences, San Diego, CA, USA., Benitez CB; Element Biosciences, San Diego, CA, USA., Berard DR; Element Biosciences, San Diego, CA, USA., Berti L; Element Biosciences, San Diego, CA, USA., Blease KN; Element Biosciences, San Diego, CA, USA., Blum AP; Element Biosciences, San Diego, CA, USA., Boddicker AM; Element Biosciences, San Diego, CA, USA., Bondar L; Element Biosciences, San Diego, CA, USA., Brown C; Element Biosciences, San Diego, CA, USA., Bui CA; Element Biosciences, San Diego, CA, USA., Calleja-Aguirre J; Element Biosciences, San Diego, CA, USA., Cappa K; Element Biosciences, San Diego, CA, USA., Chan J; Element Biosciences, San Diego, CA, USA., Chang VW; Element Biosciences, San Diego, CA, USA., Charov K; Element Biosciences, San Diego, CA, USA., Chen X; Element Biosciences, San Diego, CA, USA., Constandse RM; Element Biosciences, San Diego, CA, USA., Damron W; Element Biosciences, San Diego, CA, USA., Dawood M; Element Biosciences, San Diego, CA, USA., DeBuono N; Element Biosciences, San Diego, CA, USA., Dimalanta JD; Element Biosciences, San Diego, CA, USA., Edoli L; Element Biosciences, San Diego, CA, USA., Elango K; Element Biosciences, San Diego, CA, USA., Faustino N; Element Biosciences, San Diego, CA, USA., Feng C; Element Biosciences, San Diego, CA, USA., Ferrari M; Element Biosciences, San Diego, CA, USA., Frankie K; Element Biosciences, San Diego, CA, USA., Fries A; Element Biosciences, San Diego, CA, USA., Galloway A; Element Biosciences, San Diego, CA, USA., Gavrila V; Element Biosciences, San Diego, CA, USA., Gemmen GJ; Element Biosciences, San Diego, CA, USA., Ghadiali J; Element Biosciences, San Diego, CA, USA., Ghorbani A; Element Biosciences, San Diego, CA, USA., Goddard LA; Element Biosciences, San Diego, CA, USA., Guetter AR; Element Biosciences, San Diego, CA, USA., Hendricks GL; Element Biosciences, San Diego, CA, USA., Hentschel J; Element Biosciences, San Diego, CA, USA., Honigfort DJ; Element Biosciences, San Diego, CA, USA., Hsieh YT; Element Biosciences, San Diego, CA, USA., Hwang Fu YH; Element Biosciences, San Diego, CA, USA., Im SK; Element Biosciences, San Diego, CA, USA., Jin C; Element Biosciences, San Diego, CA, USA., Kabu S; Element Biosciences, San Diego, CA, USA., Kincade DE; Element Biosciences, San Diego, CA, USA., Levy S; Element Biosciences, San Diego, CA, USA., Li Y; Element Biosciences, San Diego, CA, USA., Liang VK; Element Biosciences, San Diego, CA, USA., Light WH; Element Biosciences, San Diego, CA, USA., Lipsher JB; Element Biosciences, San Diego, CA, USA., Liu TL; Element Biosciences, San Diego, CA, USA., Long G; Element Biosciences, San Diego, CA, USA., Ma R; Element Biosciences, San Diego, CA, USA., Mailloux JM; Element Biosciences, San Diego, CA, USA., Mandla KA; Element Biosciences, San Diego, CA, USA., Martinez AR; Element Biosciences, San Diego, CA, USA., Mass M; Element Biosciences, San Diego, CA, USA., McKean DT; Element Biosciences, San Diego, CA, USA., Meron M; Element Biosciences, San Diego, CA, USA., Miller EA; Element Biosciences, San Diego, CA, USA., Moh CS; Element Biosciences, San Diego, CA, USA., Moore RK; Element Biosciences, San Diego, CA, USA., Moreno J; Element Biosciences, San Diego, CA, USA., Neysmith JM; Element Biosciences, San Diego, CA, USA., Niman CS; Element Biosciences, San Diego, CA, USA., Nunez JM; Element Biosciences, San Diego, CA, USA., Ojeda MT; Element Biosciences, San Diego, CA, USA., Ortiz SE; Element Biosciences, San Diego, CA, USA., Owens J; Element Biosciences, San Diego, CA, USA., Piland G; Element Biosciences, San Diego, CA, USA., Proctor DJ; Element Biosciences, San Diego, CA, USA., Purba JB; Element Biosciences, San Diego, CA, USA., Ray M; Element Biosciences, San Diego, CA, USA., Rong D; Element Biosciences, San Diego, CA, USA., Saade VM; Element Biosciences, San Diego, CA, USA., Saha S; Element Biosciences, San Diego, CA, USA., Tomas GS; Element Biosciences, San Diego, CA, USA., Scheidler N; Element Biosciences, San Diego, CA, USA., Sirajudeen LH; Element Biosciences, San Diego, CA, USA., Snow S; Element Biosciences, San Diego, CA, USA., Stengel G; Element Biosciences, San Diego, CA, USA., Stinson R; Element Biosciences, San Diego, CA, USA., Stone MJ; Element Biosciences, San Diego, CA, USA., Sundseth KJ; Element Biosciences, San Diego, CA, USA., Thai E; Element Biosciences, San Diego, CA, USA., Thompson CJ; Element Biosciences, San Diego, CA, USA., Tjioe M; Element Biosciences, San Diego, CA, USA., Trejo CL; Element Biosciences, San Diego, CA, USA., Trieger G; Element Biosciences, San Diego, CA, USA., Truong DN; Element Biosciences, San Diego, CA, USA., Tse B; Element Biosciences, San Diego, CA, USA., Voiles B; Element Biosciences, San Diego, CA, USA., Vuong H; Element Biosciences, San Diego, CA, USA., Wong JC; Element Biosciences, San Diego, CA, USA., Wu CT; Element Biosciences, San Diego, CA, USA., Yu H; Element Biosciences, San Diego, CA, USA., Yu Y; Element Biosciences, San Diego, CA, USA., Yu M; Element Biosciences, San Diego, CA, USA., Zhang X; Element Biosciences, San Diego, CA, USA., Zhao D; Element Biosciences, San Diego, CA, USA., Zheng G; Element Biosciences, San Diego, CA, USA., He M; Element Biosciences, San Diego, CA, USA., Previte M; Element Biosciences, San Diego, CA, USA. mprevite@elembio.com.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2024 Jan; Vol. 42 (1), pp. 132-138. Date of Electronic Publication: 2023 May 25.

Kinetic and Structural Analysis of Two Linkers in the Tautomerase Superfamily: Analysis and Implications.

Autor: Baas BJ, Medellin BP, LeVieux JA, Erwin K, Lancaster EB, Johnson WH Jr, Kaoud TS, Moreno RY, de Ruijter M, Babbitt PC, Zhang YJ, Whitman CP

Publikováno v: Biochemistry [Biochemistry] 2021 Jun 08; Vol. 60 (22), pp. 1776-1786. Date of Electronic Publication: 2021 May 21.

Structural Characterization of the Hydratase-Aldolases, NahE and PhdJ: Implications for the Specificity, Catalysis, and N-Acetylneuraminate Lyase Subgroup of the Aldolase Superfamily.

Autor: LeVieux JA, Medellin B, Johnson WH Jr, Erwin K, Li W, Johnson IA, Zhang YJ, Whitman CP

Publikováno v: Biochemistry [Biochemistry] 2018 Jun 26; Vol. 57 (25), pp. 3524-3536. Date of Electronic Publication: 2018 Jun 11.

Kinetic and structural characterization of a cis-3-Chloroacrylic acid dehalogenase homologue in Pseudomonas sp. UW4: A potential step between subgroups in the tautomerase superfamily.

Autor: LeVieux JA; Department of Molecular Biosciences, Austin, TX 78712, USA., Baas BJ; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, Austin, TX, 78712, USA., Kaoud TS; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, Austin, TX, 78712, USA., Davidson R; Departments of Bioengineering and Therapeutic Sciences, San Francisco, CA, 94143, USA., Babbitt PC; Departments of Bioengineering and Therapeutic Sciences, San Francisco, CA, 94143, USA; Pharmaceutical Chemistry, San Francisco, CA, 94143, USA; Quantitative Biosciences Institute, University of California, San Francisco, CA, 94143, USA., Zhang YJ; Department of Molecular Biosciences, Austin, TX 78712, USA; Institute for Cellular and Molecular Biology, University of Texas, Austin, TX, 78712, USA., Whitman CP; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, Austin, TX, 78712, USA. Electronic address: whitman@austin.utexas.edu.

Publikováno v: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2017 Dec 15; Vol. 636, pp. 50-56. Date of Electronic Publication: 2017 Oct 27.