Zobrazeno 1 - 10
of 10
pro vyhledávání: '"LeRoy W. Clemence"'
Publikováno v:
Experimental Biology and Medicine. 42:12-17
Conclusions1. Sulfapyridine administered orally to rabbits is slightly less toxic than sulfanilamide. 2. Sodium sulfapyridine given intravenously is considerably more toxic than sodium sulfanilamide. 3. While the protective effect of sulfapyridine in
Autor:
George W. Raiziss, LeRoy W. Clemence
Publikováno v:
The Journal of the American Pharmaceutical Association (1912). 23:536-541
Publikováno v:
Experimental Biology and Medicine. 39:339-344
Conclusions1. 4,4′-diamino-diphenyl-sulfone is about 3 times as toxic for the rabbit as is sulfanilamide; 4,4′-diamino-diphenyl-sulfide is 5 times as toxic. 2. The corresponding diacetyl derivatives of sulfone and sulfide are less toxic than sulf
Autor:
LeRoy W. Clemence, George W. Raiziss
Publikováno v:
Journal of the American Chemical Society. 63:3124-3126
Publikováno v:
Journal of the American Chemical Society. 61:2763-2765
Publikováno v:
Journal of the American Pharmaceutical Association (Scientific ed.). 33:43-45
Autor:
LeRoy W. Clemence, Marlin T. Leffler
Publikováno v:
Journal of the American Chemical Society. 70(7)
Publikováno v:
Journal of the American Chemical Society. 63:2739-2740
Publikováno v:
Journal of the American Chemical Society. 76:4929-4930
Publikováno v:
Experimental Biology and Medicine. 40:434-435
ConclusionsWhile sulfapyridine is somewhat more potent than sulfanilamide in the treatment of Type II pneumococcic infection in mice, it does not cure the animals, but only delays death. Untreated mice survived the infection for 1 day. Twenty-four pe