Zobrazeno 1 - 6
of 6
pro vyhledávání: '"LeMoyne Habimana-Griffin"'
Autor:
Tirth K. Patel, LeMoyne Habimana-Griffin, Xuefeng Gao, Baogang Xu, Samuel Achilefu, Kari Alitalo, Celia A. McKee, Patrick W. Sheehan, Erik S. Musiek, Chengjie Xiong, Dean Coble, David M. Holtzman
Publikováno v:
Molecular Neurodegeneration, Vol 14, Iss 1, Pp 1-9 (2019)
Abstract Background Alzheimer’s disease is characterized by two main neuropathological hallmarks: extracellular plaques of amyloid-β (Aβ) protein and intracellular aggregates of tau protein. Although tau is normally a soluble monomer that bind mi
Externí odkaz:
https://doaj.org/article/dbfa7b5dd1eb4ee78e50ad04d944416b
Autor:
Nalinikanth Kotagiri, Matthew L. Cooper, Michael Rettig, Christopher Egbulefu, Julie Prior, Grace Cui, Partha Karmakar, Mingzhou Zhou, Xiaoxia Yang, Gail Sudlow, Lynne Marsala, Chantiya Chanswangphuwana, Lan Lu, LeMoyne Habimana-Griffin, Monica Shokeen, Xinming Xu, Katherine Weilbaecher, Michael Tomasson, Gregory Lanza, John F. DiPersio, Samuel Achilefu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Most of the systemic cancer therapies lack spatiotemporal control. Here, the authors show targeted activation of a light-sensitive drug by radiopharmaceuticals in disseminated cancer cells as potential in vivo treatment of metastatic diseases with re
Externí odkaz:
https://doaj.org/article/26f55b0e68cc493ba96ad8ac0b602bc1
Autor:
Avik Som, Samuel Achilefu, Kevin Guo, Sid Kurkure, Rebecca C. Gilson, Baogang Xu, Dolonchampa Maji, Shaw-Wei D. Tsen, Yang Liu, Suman B. Mondal, LeMoyne Habimana-Griffin, Walter J. Akers, Alexander Seidel, Christopher Egbulefu, Duanwen Shen, Sharon Bloch, Zohar Nussinov, Kexian Liang, Shunqiang Li, Gail Sudlow, Rui Tang
Publikováno v:
Nature Biomedical Engineering. 4:298-313
The heterogeneity and continuous genetic adaptation of tumours complicate their detection and treatment via the targeting of genetic mutations. However, hallmarks of cancer such as aberrant protein phosphorylation and calcium-mediated cell signalling
Publikováno v:
Nanomedicine
Autor:
Ramesh Raliya, Scott C. Beeman, Julie L. Prior, Annelise Y. Mah-Som, Walter J. Akers, Gail Sudlow, LeMoyne Habimana-Griffin, Samuel Achilefu, Matthew Brandenburg, Joel R. Garbow, Nathan Reed, Mark D. Pagel, Rachel High, Krishna S. Paranandi, Joseph E. Ippolito, Pratim Biswas, Avik Som
Publikováno v:
Nanomedicine (London, England). 14(2)
Aim: CaCO3 nanoparticles (nano-CaCO3) can neutralize the acidic pHe of solid tumors, but the lack of intrinsic imaging signal precludes noninvasive monitoring of pH-perturbation in tumor microenvironment. We aim to develop a theranostic version of na
Publikováno v:
Journal of biomedical optics. 22(6)
Similarity of skin cancer with many benign skin pathologies requires reliable methods to detect and differentiate the different types of these lesions. Previous studies have explored the use of disparate optical techniques to identify and estimate th