Zobrazeno 1 - 10 of 114 pro vyhledávání: '"LeDoyt, M"'
1
Akademický článek
Immunodominant extracellular loops of Treponema pallidum FadL outer membrane proteins elicit antibodies with opsonic and growth-inhibitory activities.
Autor: Delgado, Kristina N.1 (AUTHOR), Caimano, Melissa J.1,2,3,4 (AUTHOR), Orbe, Isabel C.2 (AUTHOR), Vicente, Crystal F.2 (AUTHOR), La Vake, Carson J.2 (AUTHOR), Grassmann, André A.1 (AUTHOR), Moody, M. Anthony5,6,7 (AUTHOR), Radolf, Justin D.1,2,3,4,8,9 (AUTHOR), Hawley, Kelly L.1,2,4,8,10 (AUTHOR) hawley@uchc.edu
Publikováno v: PLoS Pathogens. 12/23/2024, Vol. 20 Issue 12, p1-27. 27p.
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2
Akademický článek
Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis.
Autor: Luthra A; Department of Medicine, UConn Health, Farmington, United States of America., Montezuma-Rusca JM; Department of Medicine, UConn Health, Farmington, United States of America.; Division of Infectious Diseases, UConn Health, Farmington, United States of America.; Department of Pediatrics, UConn Health, Farmington, United States of America., La Vake CJ; Department of Pediatrics, UConn Health, Farmington, United States of America., LeDoyt M; Department of Medicine, UConn Health, Farmington, United States of America., Delgado KN; Department of Medicine, UConn Health, Farmington, United States of America., Davenport TC; Department of Medicine, UConn Health, Farmington, United States of America., Fiel-Gan M; Department of Pathology, Hartford Hospital, Hartford, United States of America., Caimano MJ; Department of Medicine, UConn Health, Farmington, United States of America.; Department of Pediatrics, UConn Health, Farmington, United States of America.; Department of Molecular Biology and Biophysics, UConn Health, Farmington, United States of America., Radolf JD; Department of Medicine, UConn Health, Farmington, United States of America.; Department of Pediatrics, UConn Health, Farmington, United States of America.; Department of Molecular Biology and Biophysics, UConn Health, Farmington, United States of America.; Department of Genetics and Genome Sciences, UConn Health, Farmington, United States of America.; Department of Immunology, UConn Health, Farmington, United States of America., Hawley KL; Department of Pediatrics, UConn Health, Farmington, United States of America.; Division of Infectious Diseases and Immunology, Connecticut Children's, Hartford, United States of America.
Publikováno v: PLoS pathogens [PLoS Pathog] 2020 Sep 16; Vol. 16 (9), pp. e1008871. Date of Electronic Publication: 2020 Sep 16 (Print Publication: 2020).
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3
Akademický článek
A bipartite bacterial virulence factor targets the complement system and neutrophil activation.
Autor: Kurniyati K; Philips Institute for Oral Health Research, School of Dentistry, Virginia Commonwealth University, Richmond, VA, USA., Clark ND; Department of Structural Biology, Jacobs School of Medicine and Biomedical Sciences, University of Buffalo, the State University of New York, Buffalo, NY, USA., Wang H; Philips Institute for Oral Health Research, School of Dentistry, Virginia Commonwealth University, Richmond, VA, USA., Deng Y; Philips Institute for Oral Health Research, School of Dentistry, Virginia Commonwealth University, Richmond, VA, USA., Sze CW; Philips Institute for Oral Health Research, School of Dentistry, Virginia Commonwealth University, Richmond, VA, USA., Visser MB; Department of Oral Biology, School of Dentistry, University of Buffalo, the State University of New York, Buffalo, NY, USA., Malkowski MG; Department of Structural Biology, Jacobs School of Medicine and Biomedical Sciences, University of Buffalo, the State University of New York, Buffalo, NY, USA. mgm22@buffalo.edu., Li C; Philips Institute for Oral Health Research, School of Dentistry, Virginia Commonwealth University, Richmond, VA, USA. cli5@vcu.edu.
Publikováno v: The EMBO journal [EMBO J] 2025 Jan 03. Date of Electronic Publication: 2025 Jan 03.
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4
Akademický článek
Phosphorylated vimentin-triggered fibronectin matrix disaggregation enhances the dissemination of Treponema pallidum subsp. pallidum across the microvascular endothelial barrier.
Autor: Luo, Xi1 (AUTHOR), Zhang, Litian1,2 (AUTHOR), Xie, Xiaoyuan1,2 (AUTHOR), Yuan, Liyan1 (AUTHOR), Shi, Yanqiang1 (AUTHOR), Jiang, Yinbo1 (AUTHOR) yinbo_j@126.com, Ke, Wujian1 (AUTHOR) kewujianstauch@163.com, Yang, Bin1,2 (AUTHOR) yangbin1@smu.edu.cn
Publikováno v: PLoS Pathogens. 9/3/2024, Vol. 20 Issue 9, p1-23. 23p.
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5
Akademický článek
Treponema pallidum genetic diversity and its implications for targeted vaccine development: A cross-sectional study of early syphilis cases in Southwestern Colombia.
Autor: Salazar, Juan C.1,2,3,4 (AUTHOR) jsalaza@connecticutchildrens.org, Vargas-Cely, Fabio4 (AUTHOR), García-Luna, Jonny A.4,5,6 (AUTHOR), Ramirez, Lady G.4,5 (AUTHOR), Bettin, Everton B.7 (AUTHOR), Romero-Rosas, Nelson4 (AUTHOR), Amórtegui, María F.4 (AUTHOR), Silva, Sebastián4 (AUTHOR), Oviedo, Oscar4 (AUTHOR), Vigil, Julie1 (AUTHOR), La Vake, Carson J.1 (AUTHOR), Galindo, Ximena8 (AUTHOR), Ramirez, Jose D.4 (AUTHOR), Martínez-Valencia, Alvaro J.4,5 (AUTHOR), Caimano, Melissa J.1,7,9 (AUTHOR), Hennelly, Christopher M.10 (AUTHOR), Aghakhanian, Farhang10 (AUTHOR), Moody, M. Anthony11,12,13 (AUTHOR), Seña, Arlene C.10 (AUTHOR), Parr, Jonathan B.10 (AUTHOR)
Publikováno v: PLoS ONE. 7/19/2024, Vol. 19 Issue 7, p1-20. 20p.
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6
Akademický článek
IFNγ Enhances CD64-Potentiated Phagocytosis of Treponema pallidum Opsonized with Human Syphilitic Serum by Human Macrophages.
Autor: Hawley KL; Department of Pediatrics, UConn Health, Farmington, CT, United States.; Division of Infectious Diseases, Connecticut Children's Medical Center, Hartford, CT, United States., Cruz AR; Centro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia., Benjamin SJ; Department of Pediatrics, UConn Health, Farmington, CT, United States.; Division of Infectious Diseases, Connecticut Children's Medical Center, Hartford, CT, United States.; Department of Immunology, UConn Health, Farmington, CT, United States., La Vake CJ; Department of Pediatrics, UConn Health, Farmington, CT, United States., Cervantes JL; Department of Pediatrics, UConn Health, Farmington, CT, United States.; Division of Infectious Diseases, Connecticut Children's Medical Center, Hartford, CT, United States., LeDoyt M; Department of Medicine, UConn Health, Farmington, CT, United States., Ramirez LG; Centro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia., Mandich D; Department of Pathology, Hartford Hospital, Hartford, CT, United States., Fiel-Gan M; Department of Pathology, Hartford Hospital, Hartford, CT, United States., Caimano MJ; Department of Medicine, UConn Health, Farmington, CT, United States., Radolf JD; Department of Pediatrics, UConn Health, Farmington, CT, United States.; Division of Infectious Diseases, Connecticut Children's Medical Center, Hartford, CT, United States.; Centro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia.; Department of Immunology, UConn Health, Farmington, CT, United States.; Department of Medicine, UConn Health, Farmington, CT, United States.; Department of Genetics and Developmental Biology, UConn Health, Farmington, CT, United States., Salazar JC; Department of Pediatrics, UConn Health, Farmington, CT, United States.; Division of Infectious Diseases, Connecticut Children's Medical Center, Hartford, CT, United States.; Centro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia.; Department of Immunology, UConn Health, Farmington, CT, United States.
Publikováno v: Frontiers in immunology [Front Immunol] 2017 Oct 05; Vol. 8, pp. 1227. Date of Electronic Publication: 2017 Oct 05 (Print Publication: 2017).
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7
Akademický článek
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8
Akademický článek
Crossing the Barrier: A Comparative Study of Listeria monocytogenes and Treponema pallidum in Placental Invasion.
Autor: Eallonardo, Samuel J.1 (AUTHOR) seallo2@uic.edu, Freitag, Nancy E.1,2 (AUTHOR) nfreitag@uic.edu
Publikováno v: Cells (2073-4409). Jan2024, Vol. 13 Issue 1, p88. 13p.
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9
Akademický článek
A Homology Model Reveals Novel Structural Features and an Immunodominant Surface Loop/Opsonic Target in the Treponema pallidum BamA Ortholog TP_0326.
Autor: Luthra A; Department of Medicine, University of Connecticut Health, Farmington, Connecticut, USA., Anand A; Department of Medicine, University of Connecticut Health, Farmington, Connecticut, USA., Hawley KL; Department of Pediatrics, University of Connecticut Health, Farmington, Connecticut, USA., LeDoyt M; Department of Medicine, University of Connecticut Health, Farmington, Connecticut, USA., La Vake CJ; Department of Pediatrics, University of Connecticut Health, Farmington, Connecticut, USA., Caimano MJ; Department of Medicine, University of Connecticut Health, Farmington, Connecticut, USA Department of Pediatrics, University of Connecticut Health, Farmington, Connecticut, USA Department of Molecular Biology and Biophysics, University of Connecticut Health, Farmington, Connecticut, USA Connecticut Children's Medical Center, Hartford, Connecticut, USA., Cruz AR; Centro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia., Salazar JC; Department of Pediatrics, University of Connecticut Health, Farmington, Connecticut, USA Connecticut Children's Medical Center, Hartford, Connecticut, USA., Radolf JD; Department of Medicine, University of Connecticut Health, Farmington, Connecticut, USA Department of Pediatrics, University of Connecticut Health, Farmington, Connecticut, USA Department of Molecular Biology and Biophysics, University of Connecticut Health, Farmington, Connecticut, USA Department of Genetics and Genomic Sciences, University of Connecticut Health, Farmington, Connecticut, USA Department of Immunology, University of Connecticut Health, Farmington, Connecticut, USA Connecticut Children's Medical Center, Hartford, Connecticut, USA JRadolf@uchc.edu.
Publikováno v: Journal of bacteriology [J Bacteriol] 2015 Jun; Vol. 197 (11), pp. 1906-20. Date of Electronic Publication: 2015 Mar 30.
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10
Akademický článek
Bipartite Topology of Treponema pallidum Repeat Proteins C/D and I: OUTER MEMBRANE INSERTION, TRIMERIZATION, AND PORIN FUNCTION REQUIRE A C-TERMINAL β-BARREL DOMAIN.
Autor: Anand A; From the Departments of Medicine., LeDoyt M; From the Departments of Medicine., Karanian C; Pediatrics., Luthra A; From the Departments of Medicine., Koszelak-Rosenblum M; the Hauptman-Woodward Medical Research Institute and., Malkowski MG; the Hauptman-Woodward Medical Research Institute and Department of Structural Biology, State University of New York, Buffalo, New York 14203, and., Puthenveetil R; the Departments of Molecular Cell Biology and., Vinogradova O; Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269., Radolf JD; From the Departments of Medicine, Pediatrics, Molecular Biology and Biophysics, Genetics and Genomic Science, and Immunology, University of Connecticut Health Center, Farmington, Connecticut 06030, JRadolf@uchc.edu.
Publikováno v: The Journal of biological chemistry [J Biol Chem] 2015 May 08; Vol. 290 (19), pp. 12313-31. Date of Electronic Publication: 2015 Mar 24.
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