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Effect of Intrawound Vancomycin Powder in Operatively Treated High-risk Tibia Fractures: A Randomized Clinical Trial.

Autor: O'Toole RV; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Joshi M; Department of Infectious Diseases, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Carlini AR; Major Extremity Trauma Research Consortium Coordinating Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Murray CK; Department of Medicine, San Antonio Military Medical Center, San Antonio, Texas., Allen LE; Major Extremity Trauma Research Consortium Coordinating Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Huang Y; Major Extremity Trauma Research Consortium Coordinating Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Scharfstein DO; Major Extremity Trauma Research Consortium Coordinating Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., O'Hara NN; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Gary JL; Department of Orthopedic Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston., Bosse MJ; Atrium Health Musculoskeletal Institute, Carolinas Medical Center, Charlotte, North Carolina., Castillo RC; Major Extremity Trauma Research Consortium Coordinating Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Bishop JA; Department of Orthopaedic Surgery, Stanford University, Palo Alto, California., Weaver MJ; Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Firoozabadi R; Department of Orthopaedics and Sports Medicine, Harborview Medical Center/University of Washington, Seattle., Hsu JR; Atrium Health Musculoskeletal Institute, Carolinas Medical Center, Charlotte, North Carolina., Karunakar MA; Atrium Health Musculoskeletal Institute, Carolinas Medical Center, Charlotte, North Carolina., Seymour RB; Atrium Health Musculoskeletal Institute, Carolinas Medical Center, Charlotte, North Carolina., Sims SH; Atrium Health Musculoskeletal Institute, Carolinas Medical Center, Charlotte, North Carolina., Churchill C; Atrium Health Musculoskeletal Institute, Carolinas Medical Center, Charlotte, North Carolina., Brennan ML; Department of Orthopaedic Surgery, Baylor Scott and White Memorial Center, Temple, Texas., Gonzales G; Department of Orthopaedic Surgery, Baylor Scott and White Memorial Center, Temple, Texas., Reilly RM; Department of Orthopaedic Surgery, Duke University, Durham, North Carolina., Zura RD; Department of Orthopaedic Surgery, Duke University, Durham, North Carolina., Howes CR; Department of Orthopaedic Surgery, Duke University, Durham, North Carolina., Mir HR; Florida Orthopaedic Institute/Tampa General Hospital, Tampa., Wagstrom EA; Department of Orthopaedic Surgery, Hennepin County Medical Center, Minneapolis, Minnesota., Westberg J; Department of Orthopaedic Surgery, Hennepin County Medical Center, Minneapolis, Minnesota., Gaski GE; Department of Orthopaedic Surgery, Indiana University Methodist Hospital, Indianapolis., Kempton LB; Department of Orthopaedic Surgery, Indiana University Methodist Hospital, Indianapolis., Natoli RM; Department of Orthopaedic Surgery, Indiana University Methodist Hospital, Indianapolis., Sorkin AT; Department of Orthopaedic Surgery, Indiana University Methodist Hospital, Indianapolis., Virkus WW; Department of Orthopaedic Surgery, Indiana University Methodist Hospital, Indianapolis., Hill LC; Department of Orthopaedic Surgery, Indiana University Methodist Hospital, Indianapolis., Hymes RA; Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Fairfax, Virginia., Holzman M; Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Fairfax, Virginia., Malekzadeh AS; Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Fairfax, Virginia., Schulman JE; Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Fairfax, Virginia., Ramsey L; Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Fairfax, Virginia., Cuff JAN; Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Fairfax, Virginia., Haaser S; Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Fairfax, Virginia., Osgood GM; Department of Orthopaedic Surgery, Johns Hopkins Hospital, Baltimore, Maryland., Shafiq B; Department of Orthopaedic Surgery, Johns Hopkins Hospital, Baltimore, Maryland., Laljani V; Department of Orthopaedic Surgery, Johns Hopkins Hospital, Baltimore, Maryland., Lee OC; Department of Orthopaedic Surgery, Louisiana State University Health Sciences Center, New Orleans., Krause PC; Department of Orthopaedic Surgery, Louisiana State University Health Sciences Center, New Orleans., Rowe CJ; Department of Orthopaedic Surgery, Louisiana State University Health Sciences Center, New Orleans., Hilliard CL; Department of Orthopaedic Surgery, Louisiana State University Health Sciences Center, New Orleans., Morandi MM; Department of Orthopaedic Surgery, Louisiana State University Health Sciences Center, Shreveport., Mullins A; Department of Orthopaedic Surgery, Louisiana State University Health Sciences Center, Shreveport., Achor TS; Department of Orthopedic Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston., Choo AM; Department of Orthopedic Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston., Munz JW; Department of Orthopedic Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston., Boutte SJ; Department of Orthopedic Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston., Vallier HA; Department of Orthopaedics, MetroHealth, Cleveland, Ohio., Breslin MA; Department of Orthopaedics, MetroHealth, Cleveland, Ohio., Frisch HM; Orthopaedic Trauma Service, Mission Health, Asheville, North Carolina., Kaufman AM; Orthopaedic Trauma Service, Mission Health, Asheville, North Carolina., Large TM; Orthopaedic Trauma Service, Mission Health, Asheville, North Carolina., LeCroy CM; Orthopaedic Trauma Service, Mission Health, Asheville, North Carolina., Riggsbee C; Research Institute, Mission Health, Asheville, North Carolina., Smith CS; Department of Orthopaedic Surgery, Naval Medical Center Portsmouth, Portsmouth, Virginia., Crickard CV; Department of Orthopaedic Surgery, Naval Medical Center Portsmouth, Portsmouth, Virginia., Phieffer LS; Department of Orthopaedics, Ohio State University, Wexner Medical Center, Columbus., Sheridan E; Department of Orthopaedics, Ohio State University, Wexner Medical Center, Columbus., Jones CB; Spectrum Health, Grand Rapids, Michigan., Sietsema DL; Spectrum Health, Grand Rapids, Michigan., Reid JS; Department of Orthopaedics and Rehabilitation, Penn State Health, Hershey, Pennsylvania., Ringenbach K; Department of Orthopaedics and Rehabilitation, Penn State Health, Hershey, Pennsylvania., Hayda R; Department of Orthopedic Surgery, Brown University/Rhode Island Hospital, Providence., Evans AR; Department of Orthopedic Surgery, Brown University/Rhode Island Hospital, Providence., Crisco MJ; Department of Orthopedic Surgery, Brown University/Rhode Island Hospital, Providence., Rivera JC; Department of Orthopaedic Surgery, San Antonio Military Medical Center, San Antonio, Texas., Osborn PM; Department of Orthopaedic Surgery, San Antonio Military Medical Center, San Antonio, Texas., Kimmel J; Department of Orthopaedic Surgery, San Antonio Military Medical Center, San Antonio, Texas., Stawicki SP; Department of Research and Innovation, St. Luke's University Health Network, Bethlehem, Pennsylvania., Nwachuku CO; Department of Orthopedic Surgery, St. Luke's University Health Network, Bethlehem, Pennsylvania., Wojda TR; Department of Family Medicine, St. Luke's University Health Network, Bethlehem, Pennsylvania., Rehman S; Department of Orthopaedic Surgery and Sports Medicine, Temple University, Philadelphia, Pennsylvania., Donnelly JM; Department of Orthopaedic Surgery and Sports Medicine, Temple University, Philadelphia, Pennsylvania., Caroom C; Department of Orthopaedics, Texas Tech University Health Sciences Center, Lubbock., Jenkins MD; Department of Orthopaedics, Texas Tech University Health Sciences Center, Lubbock., Boulton CL; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Costales TG; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., LeBrun CT; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Manson TT; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Mascarenhas DC; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Nascone JW; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Pollak AN; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Sciadini MF; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Slobogean GP; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Berger PZ; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Connelly DW; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Degani Y; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Howe AL; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Marinos DP; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Montalvo RN; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Reahl GB; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Schoonover CD; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore., Schroder LK; Department of Orthopaedic Surgery, University of Minnesota-Regions Hospital, St Paul., Vang S; Department of Orthopaedic Surgery, University of Minnesota-Regions Hospital, St Paul., Bergin PF; Department of Orthopaedic Surgery, University of Mississippi Medical Center, Jackson., Graves ML; Department of Orthopaedic Surgery, University of Mississippi Medical Center, Jackson., Russell GV; Department of Orthopaedic Surgery, University of Mississippi Medical Center, Jackson., Spitler CA; Department of Orthopaedic Surgery, University of Mississippi Medical Center, Jackson., Hydrick JM; Department of Orthopaedic Surgery, University of Mississippi Medical Center, Jackson., Teague D; Department of Orthopedic Surgery and Rehabilitation, University of Oklahoma, Oklahoma City., Ertl W; Department of Orthopedic Surgery and Rehabilitation, University of Oklahoma, Oklahoma City., Hickerson LE; Department of Orthopedic Surgery and Rehabilitation, University of Oklahoma, Oklahoma City., Moloney GB; Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania., Weinlein JC; Department of Orthopaedic Surgery, University of Tennessee-Campbell Clinic, Memphis., Zelle BA; Department of Orthopaedics, University of Texas Health at San Antonio, San Antonio., Agarwal A; Department of Orthopaedics, University of Texas Health at San Antonio, San Antonio., Karia RA; Department of Orthopaedics, University of Texas Health at San Antonio, San Antonio., Sathy AK; Department of Orthopaedic Surgery, University of Texas Southwestern Medical Center, Dallas., Au B; Department of Orthopaedic Surgery, University of Texas Southwestern Medical Center, Dallas., Maroto M; Department of Orthopaedic Surgery, University of Texas Southwestern Medical Center, Dallas., Sanders D; Department of Orthopaedic Surgery, University of Texas Southwestern Medical Center, Dallas., Higgins TF; Department of Orthopaedics, University of Utah, Salt Lake City., Haller JM; Department of Orthopaedics, University of Utah, Salt Lake City., Rothberg DL; Department of Orthopaedics, University of Utah, Salt Lake City., Weiss DB; Department of Orthopaedic Surgery, University of Virginia School of Medicine, Charlottesville., Yarboro SR; Department of Orthopaedic Surgery, University of Virginia School of Medicine, Charlottesville., McVey ED; Department of Orthopaedic Surgery, University of Virginia School of Medicine, Charlottesville., Lester-Ballard V; Department of Orthopaedic Surgery, University of Virginia School of Medicine, Charlottesville., Goodspeed D; Department of Orthopedics and Rehabilitation, University of Wisconsin School of Medicine and Public Health, Madison., Lang GJ; Department of Orthopedics and Rehabilitation, University of Wisconsin School of Medicine and Public Health, Madison., Whiting PS; Department of Orthopedics and Rehabilitation, University of Wisconsin School of Medicine and Public Health, Madison., Siy AB; Department of Orthopedics and Rehabilitation, University of Wisconsin School of Medicine and Public Health, Madison., Obremskey WT; Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee., Jahangir AA; Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee., Attum B; Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee., Burgos EJ; Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee., Molina CS; Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee., Rodriguez-Buitrago A; Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee., Gajari V; Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee., Trochez KM; Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee., Halvorson JJ; Department of Orthopaedic Surgery and Rehabilitation, Wake Forest Baptist University Medical Center, Winston-Salem, North Carolina., Miller AN; Department of Orthopaedic Surgery and Rehabilitation, Wake Forest Baptist University Medical Center, Winston-Salem, North Carolina., Goodman JB; Department of Orthopaedic Surgery and Rehabilitation, Wake Forest Baptist University Medical Center, Winston-Salem, North Carolina., Holden MB; Department of Orthopaedic Surgery and Rehabilitation, Wake Forest Baptist University Medical Center, Winston-Salem, North Carolina., McAndrew CM; Department of Orthopedic Surgery, Washington University in St Louis/Barnes Jewish Hospital, St Louis, Missouri., Gardner MJ; Department of Orthopedic Surgery, Washington University in St Louis/Barnes Jewish Hospital, St Louis, Missouri., Ricci WM; Department of Orthopedic Surgery, Washington University in St Louis/Barnes Jewish Hospital, St Louis, Missouri., Spraggs-Hughes A; Department of Orthopedic Surgery, Washington University in St Louis/Barnes Jewish Hospital, St Louis, Missouri., Collins SC; Major Extremity Trauma Research Consortium Coordinating Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Taylor TJ; Major Extremity Trauma Research Consortium Coordinating Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Zadnik M; Major Extremity Trauma Research Consortium Coordinating Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

Publikováno v: JAMA surgery [JAMA Surg] 2021 May 01; Vol. 156 (5), pp. e207259. Date of Electronic Publication: 2021 May 12.