Intravital imaging of islet Ca2+ dynamics reveals enhanced beta cell connectivity after bariatric surgery in mice (vol 12, 5165, 2021)

Autor: Akalestou, E, Suba, K, Lopez-Noriega, L, Georgiadou, E, Chabosseau, P, Gallie, A, Wretlind, A, Legido-Quigley, C, Leclerc, I, Salem, V, Rutter, GA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::83ce3e0d839d14838a64457604837b8d
http://hdl.handle.net/10044/1/94116

The Ca2+-binding protein sorcin stimulates transcriptional activity of the unfolded protein response mediator ATF6

Autor: Parks, SZ, Gao, T, Awuapura, NJ, Ayathamattam, J, Chabosseau, PL, Kalvakolanu, D, Valdivia, HH, Rutter, GA, Leclerc, I, Nakatogawa, H

Sorcin is a calcium-binding protein involved in maintaining endoplasmic reticulum (ER) Ca2+ stores. We have previously shown that overexpressing sorcin under the rat insulin promoter was protective against high fat diet-induced pancreatic beta cell d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3295e23f14fce86f5cdf8af758c55d2
http://hdl.handle.net/10044/1/89478

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Occupational contact urticaria: lessons from the French National Network for Occupational Disease Vigilance and Prevention (RNV3P)

Autor: Bensefa-Colas, L., Telle-Lamberton, M., Faye, S., Bourrain, J.-L., Crépy, M.-N., Lasfargues, Gérard, Choudat, D., Le Barbier, M., Marny, C., Doutrellot-Philippon, C., Gislard, Antoine, Gehanno, Jean-François, Rollin, Laetitia, Roquelaure, Yves, Petit, Audrey, Verdun-Esquer, Catherine, Leclerc, I., Dewitte, J.D., Loddé, B., Clin, B., Momas, I., Barbier, M. Le, Marquignon, M.F., Chamoux, A., Dutheil, F., Andujar, P., Pairon, J.C., Smolik, H.J., Fernandez, N., Bonneterre, V., Michel, E., Gehanno, J.F., Frimat, P., Nisse, C., Druet-Cabanac, M., Massardier, A., CHARBOTEL, B., Lehucher-Michel, M.P., Roulet, A., Lesage, F.X., Paris, C., Penven, E., Dupas, D., Descatha, A., Mediouni, Z., Léger, D., Bayon, V., Langrand, J., Villa, A., Ben-Brik, E., Martinez, H., Deschamps, F., Gouyet, T., Verger, C., FONTANA, L., Pélissier, C., Gonzalez, M., Nourry, N., Esquirol, Y., Hérin, F., Haguenoer, K.

Publikováno v: British Journal of Dermatology
British Journal of Dermatology, Wiley, 2015, 173 (6), pp.1453-1461. ⟨10.1111/bjd.14050⟩
British Journal of Dermatology, 2015, 173 (6), pp.1453-1461. ⟨10.1111/bjd.14050⟩

Summary Background Occupational contact urticaria (OCU) is an occupational contact dermatitis that can cause serious health consequences and disability at work. Objectives To describe OCU and its temporal trends by the main causal agents and activity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f6020332217927bbf41cdc5d0f03c0
https://doi.org/10.1111/bjd.14050

Decreased STARD10 expression is associated with defective insulin secretion in humans and mice

Autor: Carrat, GR, Hu, M, Nguyen-Tu, M-S, Chabosseau, P, Gaulton, KJ, van de Bunt, M, Siddiq, A, Falchi, M, Thurner, M, Canouil, M, Pattou, F, Leclerc, I, Pullen, TJ, Cane, MC, Prabhala, P, Greenwald, W, Schulte, A, Marchetti, P, Ibberson, M, MacDonald, PE, Manning Fox, JE, Gloyn, AL, Froguel, P, Solimena, M, McCarthy, M, Rutter, GA

Publikováno v: American journal of human genetics, vol 100, iss 2
American journal of human genetics
Am. J. Hum. Genet. 100, 238-256 (2017)
Carrat, G R, Hu, M, Nguyen-Tu, M-S, Chabosseau, P, Gaulton, K J, van de Bunt, M, Siddiq, A, Falchi, M, Thurner, M, Canouil, M, Pattou, F, Leclerc, I, Pullen, T J, Cane, M C, Prabhala, P, Greenwald, W, Schulte, A, Marchetti, P, Ibberson, M, MacDonald, P E, Manning Fox, J E, Gloyn, A L, Froguel, P, Solimena, M, McCarthy, M I & Rutter, G A 2017, ' Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice ', American Journal of Human Genetics, vol. 100, no. 2, pp. 238-256 . https://doi.org/10.1016/j.ajhg.2017.01.011

Genetic variants near ARAP1 (CENTD2) and STARD10 influence type 2 diabetes (T2D) risk. The risk alleles impair glucose-induced insulin secretion and, paradoxically but characteristically, are associated with decreased proinsulin:insulin ratios, indic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2411d210afb9ad789dced93b5259a382
http://publikationen.ub.uni-frankfurt.de/files/33574/container.zip