Výsledky vyhledávání - "LeAnn J. Godderz"

DNA Cleavage of a Cryptic Recombination Signal Sequence by RAG1 and RAG2

Autor: LeAnn J. Godderz, J. Donald Capra, Stephen J. Stray, Karla K. Rodgers, Negar S. Rahman

Publikováno v: Journal of Biological Chemistry. 281:12370-12380

Antibody and T cell receptor genes are assembled from gene segments by V(D)J recombination to produce an almost infinitely diverse repertoire of antigen specificities. Recombination is initiated by cleavage of conserved recombination signal sequences

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e738fc48929ba3a64fbae2af185100b8
https://doi.org/10.1074/jbc.m507906200

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Analysis of Biological Macromolecular Assemblies Using Static Light Scattering Methods

Autor: Mandy M. Peak, Karla K. Rodgers, LeAnn J. Godderz

Publikováno v: Current Organic Chemistry. 9:899-908

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25d79db1e396e63a1100087820148c4f
https://doi.org/10.2174/1385272054038246

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Self-association and conformational properties of RAG1: implications for formation of the V(D)J recombinase

Autor: Negar S. Rahman, LeAnn J. Godderz, Karla K. Rodgers, Janeen L. Arbuckle, George M. Risinger

Publikováno v: Nucleic Acids Research. 31:2014-2023

RAG1 and RAG2 catalyze the initial DNA cleavage steps in V(D)J recombination. Fundamental properties of these proteins remain largely unknown. Here, self-association and conformational properties of murine core RAG1 (residues 384-1008) were examined.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1eb707f811bb32a30099c4ce8d6d7a
https://doi.org/10.1093/nar/gkg281

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DNA cleavage of a cryptic recombination signal sequence by RAG1 and RAG2. Implications for partial V(H) gene replacement

Autor: Negar S, Rahman, LeAnn J, Godderz, Stephen J, Stray, J Donald, Capra, Karla K, Rodgers

Publikováno v: The Journal of biological chemistry. 281(18)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0239210287eaf100f4779a7d1e2258a9
https://pubmed.ncbi.nlm.nih.gov/16531612

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Thermal dependency of RAG1 self-association properties

Autor: Karla K. Rodgers, LeAnn J. Godderz, Lori M. Gwyn, Shuying Zhao, Mandy M. Peak, Pallabi De

Publikováno v: BMC Biochemistry
BMC Biochemistry, Vol 9, Iss 1, p 5 (2008)

Background Functional immunoglobulin and T cell receptor genes are produced in developing lymphocytes by V(D)J recombination. The initial site-specific DNA cleavage steps in this process are catalyzed by the V(D)J recombinase, consisting of RAG1 and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4ad43d36c6bc39279ad6a4a77ab467
http://europepmc.org/articles/PMC2270275

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