Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Le-le Zhang"'
Autor:
Dan-Ling Dai, Chu Xie, Lan-Yi Zhong, Shang-Xin Liu, Le-Le Zhang, Hua Zhang, Xing-Ping Wu, Zhou-Ming Wu, Kexin Kang, Yan Li, Ya-Meng Sun, Tian-Liang Xia, Chen-Song Zhang, Ao Zhang, Ming Shi, Cong Sun, Mei-Ling Chen, Ge-Xin Zhao, Guo-Long Bu, Yuan-Tao Liu, Kui-Yuan Huang, Zheng Zhao, Shu-Xin Li, Xiao-Yong Zhang, Yun-Fei Yuan, Shi-Jun Wen, Lingqiang Zhang, Bin-Kui Li, Qian Zhong, Mu-Sheng Zeng
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Axis inhibition protein 1 (AXIN1), a scaffold protein interacting with various critical molecules, plays a vital role in determining cell fate. However, its impact on the antiviral innate immune response remains largely unknown. Here, we ide
Externí odkaz:
https://doaj.org/article/b3dcd05ee9ce45538c46a6f7a93e85d6
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionFear memory formation has been implicated in fear- and stress-related psychiatric disorders, including post-traumatic stress disorder (PTSD) and phobias. Synapse deficiency and microglial activation are common among patients with PTSD, an
Externí odkaz:
https://doaj.org/article/742cb5727bf842a0b4a9fa3b8e09d9de
Autor:
Jing-hua Gao, Yue-ying Liu, Hui-xiang Xu, Ke Wu, Le-le Zhang, Peng Cheng, Xiao-han Peng, Jun-li Cao, Rong Hua, Yong-mei Zhang
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110886- (2024)
Summary: Somatostatin (SOM)-expressing neurons in the central lateral amygdala (CeL) are responsible for fear memory learning, but the circuit and molecular mechanisms underlying this biology remain elusive. Here, we found that glutamatergic neurons
Externí odkaz:
https://doaj.org/article/19199a3d42d446c397ff4b852046b12b
Autor:
Xu-Jia Chen, Zhou Deng, Le-Le Zhang, Yan Pan, Jia Fu, Liang Zou, Zhaofang Bai, Xiaohe Xiao, Feiya Sheng
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 172, Iss , Pp 116222- (2024)
Alzheimer’s disease (AD) is a high-incidence neurodegenerative disorder, characterized by cognitive impairment, memory loss, and psychiatric abnormalities. Ganoderma lucidum is a famous medicinal fungus with a long history of dietary intake, contai
Externí odkaz:
https://doaj.org/article/8a4c847194144e3ea98257855f383de3
Autor:
Min-Xia Su, Yu-Lian Xu, Xiao-Ming Jiang, Mu-Yang Huang, Le-Le Zhang, Luo-Wei Yuan, Xiao-Huang Xu, Qi Zhu, Jian-Li Gao, Jia-Hong Lu, Xiuping Chen, Ming-Qing Huang, Yitao Wang, Jin-Jian Lu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 3, Pp 1240-1253 (2022)
The mammalian target of rapamycin (mTOR) pathway is abnormally activated in lung cancer. However, the anti-lung cancer effect of mTOR inhibitors as monotherapy is modest. Here, we identified that ginsenoside Rh2, an active component of Panax ginseng
Externí odkaz:
https://doaj.org/article/dc390603aa844426b73e68a3e9210154
Autor:
Le-Le Zhang, Yan He, Feiya Sheng, Ying-Fan Hu, Yu Song, Wei Li, Jiarong Chen, Jinming Zhang, Liang Zou
Publikováno v:
Chinese Medicine, Vol 16, Iss 1, Pp 1-18 (2021)
Abstract Fagopyrum dibotrys (F. dibotrys) (D.Don) H.Hara is a well-known edible herbal medicine in Asian countries. It has been widely used for the treatment of lung diseases, swelling, etc., and is also an important part of many Chinese medicine pre
Externí odkaz:
https://doaj.org/article/99bf84afb5954cddb9d25bf2997460d3
Autor:
Yu‐Lian Xu, Luo‐Wei Yuan, Xiao‐Ming Jiang, Min‐Xia Su, Mu‐Yang Huang, Yu‐Chi Chen, Le‐Le Zhang, Xiuping Chen, Hong Zhu, Jin‐Jian Lu
Publikováno v:
MedComm, Vol 3, Iss 3, Pp n/a-n/a (2022)
Abstract Lung cancer is the leading cause of cancer death worldwide, of which lung adenocarcinoma (LUAD) is the most common subtype. Metastasis is the major cause of poor prognosis and mortality for lung cancer patients, which urgently needs great ef
Externí odkaz:
https://doaj.org/article/19de3db6b31944489e11f82262f5ba1f
Autor:
Peng Yin, Sulei Hu, Kun Qian, Zeyue Wei, Le-Le Zhang, Yue Lin, Weixin Huang, Haifeng Xiong, Wei-Xue Li, Hai-Wei Liang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Deactivation of supported metal catalysts via thermally induced sintering is a major concern in the catalysis community. Here, the authors demonstrate that enlarging particle distance to over the critical distance could suppress the particle coalesce
Externí odkaz:
https://doaj.org/article/8eac23c06c724912b4a65d740575216e
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-10 (2020)
Abstract Background Despite the effective antiretroviral treatment (ART) of HIV-infected individuals, HIV persists in a small pool. Central memory CD4+ T cells (Tcm) make a major contribution to HIV persistence. We found that unlike HLA-DR, CD38 is h
Externí odkaz:
https://doaj.org/article/5715e153955740b983e6e332fa5faf2d
Autor:
Cheng-Feng Han, Shu-Ting Liu, Rong-Rong Yan, Jian Li, Ni Chen, Le-Le Zhang, Shi-Ru Jia, Pei-Pei Han
Publikováno v:
Foods, Vol 12, Iss 5, p 915 (2023)
To significantly improve the polysaccharide production of Nostoc flagelliforme, a total of 12 chemicals were evaluated for their effects on polysaccharide accumulation. The results showed that salicylic acid and jasmonic acid increased the accumulati
Externí odkaz:
https://doaj.org/article/f3345e40d2104d0cacafed1df84dd94c