Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Le-Le Zhou"'
Publikováno v:
Journal of the American Chemical Society. 145:1475-1496
Publikováno v:
Chemical Science. 14:3642-3651
An iodide-containing cationic covalent organic framework as a nonmetallic radiosensitizer increases X-ray deposition and enhances radiotherapy of colon cancer in vitro and in vivo by inducing ferroptosis.
Autor:
Wen-Yan Li, Jing-Jing Wan, Jing-Lan Kan, Bo Wang, Tian Song, Qun Guan, Le-Le Zhou, Yan-An Li, Yu-Bin Dong
Publikováno v:
Chemical Science. 14:1453-1460
Stimulus-responsive biodegradable nanocarriers with tumor-selective targeted drug delivery are critical for cancer therapy.
Autor:
Wen-Yan Li, Jing-Lan Kan, Jing-Jing Wan, Yan-An Li, Tian Song, Bo Wang, Qun Guan, Le-Le Zhou, Yu-Bin Dong
Publikováno v:
Chemical Communications. 59:5423-5426
Herein, we report the first reactive oxygen species (ROS)-responsive dithioketal-linked covalent organic framework (COF) for synergetic chemotherapy and photodynamic therapy (PDT) of cancer.
Publikováno v:
Journal of Materials Chemistry B. 10:8894-8909
Intracellular cysteine depletion induced by a COF-based click photoreaction achieves effective cancer therapy by ferroptosis.
Publikováno v:
Chemical Society Reviews. 51:6307-6416
Covalent organic frameworks (COFs) are a class of organic crystalline porous materials discovered in the early 21st century that have become an attractive class of emerging materials due to their high crystallinity, intrinsic porosity, structural reg
Publikováno v:
Chemical science. 13(26)
Small interfering RNA (siRNA)-mediated gene silencing is a promising therapeutic approach. Herein, we report the ambient synthesis of a positively charged iminium-linked covalent organic framework by a three-component one-pot reaction. Through anion
Publikováno v:
Angewandte Chemie International Edition. 59:18042-18047
Ca2+ , a ubiquitous but nuanced modulator of cellular physiology, is meticulously controlled intracellularly. However, intracellular Ca2+ regulation, such as mitochondrial Ca2+ buffering capacity, can be disrupted by 1 O2 . Thus, the intracellular Ca
Autor:
Le-Le Zhou, Qun Guan, Li-Na Zhou, Meng-Di Li, Yan-An Li, Yu-Bin Dong, Guo-Xin Qin, Wen-Yan Li
Publikováno v:
Chemical Communications. 56:7793-7796
Herein, we report a microporous carbon nanomaterial that was generated from a nanoscale covalent organic framework precursor via a simple pyrolysis approach. The obtained carbon-based nanoparticles possessed a broad NIR absorption capacity and exhibi
Publikováno v:
Zhonghua nan ke xue = National journal of andrology. 27(4)
Heat shock protein 90 (Hsp90), as a member of the Hsp family and widely found in the gonads of humans and animals, plays an essential role in male reproduction and induces various changes in the process of reproduction. Hsp90 regulates the division o