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Inhibition of trypsin by carbobenzyloxylysyl chloromethyl ketone: 13C NMR and x-ray diffraction analyses of the enzyme-inhibitor complex

Autor: Yi Jin Jang, N. E. Mackenzie, J P G Malthouse, A. Brisson, Le Zong Qi, Paul E. Fagerness, A. I. Scott, Carl M. Carter, W. U. Primrose, W. Bode

Publikováno v: Tetrahedron. 42:3269-3276

Comparison of the X-ray diffraction data and both solution and solid (CPMAS) NMR spectra for the covalent adduct of trypsin and carbobenzyloxylysyl chloromethyl ketone provides unequivocal evidence that the serine-195 hydroxyl group of the enzyme for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7c123b55204f2966710d4d95a4ca2910
https://doi.org/10.1016/s0040-4020(01)87391-9

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