Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Le Z Day"'
Autor:
Stanislav Listopad, Christophe Magnan, Le Z Day, Aliya Asghar, Andrew Stolz, John A Tayek, Zhang-Xu Liu, Jon M Jacobs, Timothy R Morgan, Trina M Norden-Krichmar
Publikováno v:
PLOS Digital Health, Vol 3, Iss 2, p e0000447 (2024)
Distinguishing between alcohol-associated hepatitis (AH) and alcohol-associated cirrhosis (AC) remains a diagnostic challenge. In this study, we used machine learning with transcriptomics and proteomics data from liver tissue and peripheral mononucle
Externí odkaz:
https://doaj.org/article/70c69694d50b4a10aa033ee82af3e165
Autor:
Josepmaria Argemi, Komal Kedia, Marina A. Gritsenko, Ana Clemente-Sanchez, Aliya Asghar, Jose M. Herranz, Zhang-Xu Liu, Stephen R. Atkinson, Richard D. Smith, Trina M. Norden-Krichmar, Le Z. Day, Andrew Stolz, John A. Tayek, Ramon Bataller, Timothy R. Morgan, Jon M. Jacobs
Publikováno v:
The American Journal of Pathology. 192:1658-1669
Alcohol-associated hepatitis (AH) is a form of liver failure with high short-term mortality. Recent studies have shown that defective function of hepatocyte nuclear factor 4 alpha (HNF4a) and systemic inflammation are major disease drivers of AH. Pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fe3b65b19b8fcbfb473c24435922b8c
https://doi.org/10.1016/j.ajpath.2022.08.009
https://doi.org/10.1016/j.ajpath.2022.08.009
Autor:
Sara JC Gosline, Marija Velickovic, James Pino, Le Z. Day, Isaac K. Attah, Adam C. Swensen, Vincent Danna, Karin D. Rodland, Jing Chen, Clayton E. Matthews, Martha Campbell-Thompson, Julia Laskin, Kristin Burnum-Johnson, Ying Zhu, Paul D. Piehowski
The need for a clinically accessible method with the ability to match protein activity within heterogeneous tissues is currently unmet by existing technologies. Our proteomics sample preparation platform, named microPOTS (Microdroplet Processing in O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68952b7c091c82e33c16a258f9c6dd56
https://doi.org/10.1101/2022.11.21.517388
https://doi.org/10.1101/2022.11.21.517388
Autor:
Xiaoqin Wu, Xiude Fan, Megan R. McMullen, Tatsunori Miyata, Adam Kim, Vai Pathak, Jianguo Wu, Le Z. Day, Josiah E. Hardesty, Nicole Welch, Jaividhya Dasarathy, Daniela S. Allende, Arthur J. McCullough, Jon M. Jacobs, Daniel M. Rotroff, Srinivasan Dasarathy, Laura E. Nagy
Publikováno v:
Hepatology (Baltimore, Md.)REFERENCES.
Mixed lineage kinase domain-like pseudokinase (MLKL), a key terminal effector of necroptosis, also plays a role in intracellular vesicle trafficking that is critical for regulating liver inflammation and injury in alcohol-associated liver disease (AL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211e6653797dbde70e1195746b135e3d
https://pubmed.ncbi.nlm.nih.gov/35689613
https://pubmed.ncbi.nlm.nih.gov/35689613
Autor:
Adam C. Swensen, Dušan Veličković, Sarah M. Williams, Ronald J. Moore, Le Z. Day, Sherry Niessen, Sarah Hennessy, Camilo Posso, Mara Monetti, Wei-Jun Qian, Jon Jacobs, Laurence Whiteley, Ying Zhu, Paul D. Piehowski
Publikováno v:
Molecularcellular proteomics : MCP. 21(12)
Despite their diminutive size, islets of Langerhans play a large role in maintaining systemic energy balance in the body. New technologies have enabled us to go from studying the whole pancreas to isolated whole islets, to partial islet sections, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c8c408b83a112b27478b8b5393cd0f
https://pubmed.ncbi.nlm.nih.gov/36244662
https://pubmed.ncbi.nlm.nih.gov/36244662
Autor:
Listopad, Stanislav, Magnan, Christophe, Day, Le Z., Asghar, Aliya, Stolz, Andrew, Tayek, John A., Liu, Zhang-Xu, Jacobs, Jon M., Morgan, Timothy R., Norden-Krichmar, Trina M.
Publikováno v:
PLoS Digital Health; 2/9/2024, Vol. 3 Issue 2, p1-16, 16p
Publikováno v:
Hepatitis Weekly; 6/17/2024, p368-368, 1p
Publikováno v:
Hepatitis Weekly; 3/13/2023, p475-475, 1p