Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Le Thi Duong"'
Autor:
Donald B. Kimmel, David B. Gilberto, Nicholas T Gatto, Rana Samadfam, Brenda L Pennypacker, Le Thi Duong, Susan Y. Smith
Publikováno v:
Journal of Orthopaedic Research. 34:72-80
The effects of the cathepsin K inhibitor odanacatib (ODN) on fracture healing were monitored for ∼6 and 15 weeks post-fracture in two separate studies using the unilateral transverse mid-ulnar osteotomy model in skeletally mature female rabbits. Ra
Autor:
Mei Wan, Changjun Li, Long Wang, Liang Xie, Zhuang Cui, Janet L. Crane, Weizhong Chang, Qin Bian, Bin Yu, Maureen Pickarski, Hui Xie, Xiang-Hang Luo, Gehua Zhen, Yin Hu, Zhuying Xia, Jolene J. Windle, Er-Yuan Liao, Tao Qiu, Le Thi Duong, Xu Cao, Lingling Xian
Publikováno v:
Nature medicine
Osteogenesis during bone modeling and remodeling is coupled with angiogenesis. A recent study showed that a specific vessel subtype, strongly positive for CD31 and endomucin (CD31(hi)Emcn(hi)), couples angiogenesis and osteogenesis. Here, we found th
Autor:
Maureen Pickarski, Denis Riendeau, Paul Tawa, Le Thi Duong, Sonia Lamontagne, W. Cameron Black, M. David Percival, Renata Oballa, Sylvie Desmarais
Publikováno v:
Molecular Pharmacology. 73:147-156
Cathepsin K is a lysosomal cysteine protease that is a pharmacological target for the treatment of osteoporosis. Previous studies showed that basic, lipophilic cathepsin K inhibitors are lysosomotropic and have greater activities in cell-based assays
Publikováno v:
Bone. 67
The cathepsin K (CatK) inhibitor odanacatib (ODN) is currently being developed for the treatment of osteoporosis. In clinical trials, efficacy and resolution of effect of ODN treatment on bone turnover biomarkers and accrued bone mass have been demon
Akademický článek
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Autor:
Alexandre Coimbra, Donald S. Williams, Guoyuan Liang, Jacob M. Elkins, Punam K. Saha, Milan Sonka, Le Thi Duong
Publikováno v:
Medical Imaging: Image Processing
Osteophyte is an additional bony growth on a normal bone surface limiting or stopping motion in a deteriorating joint. Detection and quantification of osteophytes from CT images is helpful in assessing disease status as well as treatment and surgery
Autor:
Jayme Jensen, Maureen Pickarski, Guojie Ho, Cyrille Sur, Le Thi Duong, Alexa Gleason, Jun Zhang, Garry Cuneo, Bohumil Bednar, Renee C. Gaspar, Milind Rajopadhye, Shu-An Lin, Wael Yared, George D. Hartman, Chiara Buono, Agnieszka Blusztajn, Richard Hargreaves, Paul J. Coleman, Jeffrey D. Peterson, Sylvie Kossodo
Publikováno v:
Molecular imaging and biology. 12(5)
Integrins, especially α(v)β(3) and α(v)β(5), are upregulated in tumor cells and activated endothelial cells and as such, serve as cancer biomarkers. We developed a novel near-infrared-labeled optical agent for the in vivo detection and quantifica
Akademický článek
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Autor:
Kossodo, Sylvie, Pickarski, Maureen, Shu-An Lin, Gleason, Alexa, Gaspar, Renee, Buono, Chiara, Ho, Guojie, Blusztajn, Agnieszka, Cuneo, Garry, Jun Zhang, Jensen, Jayme, Hargreaves, Richard, Coleman, Paul, Hartman, George, Rajopadhye, Milind, Le Thi Duong, Sur, Cyrille, Yared, Wael, Peterson, Jeffrey, Bednar, Bohumil
Publikováno v:
Molecular Imaging & Biology; Oct2010, Vol. 12 Issue 5, p488-499, 12p, 1 Chart, 7 Graphs