Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Le Shara M. Fulton"'
Autor:
Nicholas A. Taylor, James E. Bear, James M. Coghill, Matthew E. Berginski, Timothy P. Moran, Kaifeng Lisa Lin, Bruce R. Blazar, Michelle L. West, Jonathan S. Serody, Le Shara M. Fulton
Publikováno v:
Blood. 123:1604-1614
Graft-versus-host disease (GVHD) is a systemic inflammatory response due to the recognition of major histocompatibility complex disparity between donor and recipient after hematopoietic stem cell transplantation (HSCT). T-cell activation is critical
Autor:
Jonathan S. Serody, Angela Panoskaltsis-Mortari, Michelle L. West, Donald N. Cook, Kaifeng Lin, Benjamin G. Vincent, Le Shara M. Fulton, James M. Coghill, Bruce R. Blazar, Karen P. McKinnon, Kenneth A. Fowler, Hendrik W. van Deventer
Publikováno v:
Blood. 122:825-836
The infusion of donor regulatory T cells (Tregs) has been used to prevent acute graft-versus-host disease (GVHD) in mice and has shown promise in phase 1 clinical trials. Previous work suggested that early Treg migration into lymphoid tissue was impo
Autor:
Dan R. Littman, Michelle L. West, Laura E. Ott, Michael J. Carlson, Bruce R. Blazar, Jonathan S. Serody, Angela Panoskaltsis-Mortari, James M. Coghill, Le Shara M. Fulton
Publikováno v:
The Journal of Immunology. 189:1765-1772
Graft-versus-host disease (GVHD) remains the most significant complication after allogeneic stem cell transplantation. Previously, acute GVHD had been considered to be mediated predominantly by Th1-polarized T cells. Recently, investigators have iden
Autor:
Henrik Frydenlund Hansen, Maria A. Graziewicz, Jennifer Roberts, Ryszard Kole, Henrik Ørum, Peter Sazani, Brian K. Buckley, Le Shara M. Fulton, Teresa K. Tarrant
Publikováno v:
Molecular Therapy
Tumor necrosis factor-alpha (TNF-alpha) is a key mediator of inflammatory diseases, including rheumatoid arthritis (RA), and anti-TNF-alpha drugs such as etanercept are effective treatments. Splice-switching oligonucleotides (SSOs) are a new class of