Invalidation of the transcriptional modulator of lipid metabolism PPARβ/δ in T cells prevents age-related alteration of body composition and loss of endurance capacity

Autor: Rousseau, A.S., Murdaca, J., Le Menn, G., Sibille, B., Wahli, W., Le Garf, S., Chinetti, G., Neels, J.G., Mothe-Satney, I.

Publikováno v: Frontiers in Physiology
Frontiers in Physiology, Frontiers, 2021, 12, ⟨10.3389/fphys.2021.587753⟩
Frontiers in Physiology, 2021, 12, ⟨10.3389/fphys.2021.587753⟩
Frontiers in physiology, vol. 12, pp. 587753

Anti-inflammatory regulatory T cells (Tregs) are the most metabolically flexible CD4⁺ T cells by using both glycolysis and fatty acid oxidation (FAO) which allow them to migrate in tissues. With aging, Tregs accumulate in secondary lymphoid organs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::53314923ac4773932046f32d53d3dea3
https://hdl.handle.net/10356/151773

034 Dysfunctional Collagen XVII provokes skin inflammation

Autor: Lindgren, O., Tuusa, J., Le Menn, G., Chen, Z., Tasanen, K., Kokkonen, N.

Publikováno v: In Journal of Investigative Dermatology October 2021 141(10) Supplement:S154-S154

Genetic Variants of Serum Alpha-1-Antitrypsin (Pi Types) in a Breton Population, the Bigoudens

Autor: Youinou, P., Gueguen, A., Martin, J.P., Jouquan, J., Salmon, D., Ruffie, J., Le Menn, G., Salmon, C.

Publikováno v: Human Heredity, 1984 Jan 01. 34(2), 114-119.

Externí odkaz: https://www.jstor.org/stable/45101809

Conséquences immuno-métaboliques d’une activation de la voie PPARbeta dans le traitement de l’obésité chez la souris

Autor: Le Garf, S., Murdaca, J., Mothe-Satney, I., Le Menn, G., Sibille, B., Neels, J., Rousseau, A.-S.

Publikováno v: In Nutrition clinique et métabolisme March 2019 33(1):80-81

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