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C3a modulates IL-1β secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation

Autor: Asgari, Elham, Le Friec, Gaelle, Yamamoto, Hidekazu, Perucha, Esperanza, Sacks, Steven S., Köhl, Jörg, Cook, H. Terence, Kemper, Claudia

Publikováno v: In Blood 14 November 2013 122(20):3473-3481

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Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism

Autor: Arbore, Giuseppina, West, Erin, Rahman, Jubayer, Le Friec, Gaelle, Niyonzima, Nathalie, Mehdi, Pirooznia, Ilker, Tunc, Polychronis, Pavlidis, Nicholas, Powell, Li, Yuesheng, Liu, Poching, Servais, Aude, Couzi, Lionel, Fremeaux-Bacchi, Veronique, Placais, Leo, Ferraro, Alastair, Walsh, Patrick R., Kavanagh, David, Afzali, Behdad, Lavender, Paul, Lachmann, Helen J., Kemper, Claudia

Externí odkaz: http://hdl.handle.net/11250/2594386

Dysregulated CD46 shedding interferes with Th1-contraction in systemic lupus erythematosus

Autor: Ellinghaus, Ursula, Cortini, Andrea, Pinder, Christopher L., Le Friec, Gaelle, Kemper, Claudia, Vyse, Timothy J.

Publikováno v: Ellinghaus, U, Cortini, A, Pinder, C L, Le Friec, G, Kemper, C & Vyse, T J 2017, ' Dysregulated CD46 shedding interferes with Th1-contraction in systemic lupus erythematosus ', European Journal of Immunology, vol. 47, no. 7, pp. 1200-1210 . https://doi.org/10.1002/eji.201646822
European Journal of Immunology

IFN-γ-producing T helper 1 (Th1) cell responses mediate protection against infections but uncontrolled Th1 activity also contributes to a broad range of autoimmune diseases. Autocrine complement activation has recently emerged as key in the inductio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a871da5264b03a45d6a4061aafcceb90
https://kclpure.kcl.ac.uk/ws/files/71591867/Disregulated_CD46_shedding_interferes_Publishedonline22May2017_GOLD_VoR_CC_BY_.pdf