Covalent Linkages of Molecules and Proteins to Si-H Surfaces Formed by Disulfide Reduction

Autor: Dief, EM, Vogel, YB, Peiris, CR, Le Brun, AP, Gonçales, VR, Ciampi, S, Reimers, JR, Darwish, N

Thiols and disulfide contacts have been, for decades, key for connecting organic molecules to surfaces and nanoclusters as they form self-assembled monolayers (SAMs) on metals such as gold (Au) under mild conditions. In contrast, they have not been s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______363::9b329c13309aad21cd9ed0d752d581a4
https://hdl.handle.net/10453/144731

Evidence of the Key Role of H3O+ in Phospholipid Membrane Morphology

Autor: Cranfield, CG, Berry, T, Holt, SA, Hossain, KR, Le Brun, AP, Carne, S, Al Khamici, H, Coster, H, Valenzuela, SM, Cornell, B

© 2016 American Chemical Society. This study explains the importance of the phosphate moiety and H3O+ in controlling the ionic flux through phospholipid membranes. We show that despite an increase in the H3O+ concentration when the pH is decreased,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______363::66d977332dc29d210fbf9858d0e3a622
https://hdl.handle.net/10453/54908

Deuterium Labeling Strategies for Creating Contrast in Structure–Function Studies of Model Bacterial Outer Membranes Using Neutron Reflectometry

Autor: Stephen A. Holt, Jeremy H. Lakey, PJ Holden, Le, Brun, Ap, Luke A. Clifton

Studying the outer membrane of Gram-negative bacteria is challenging due to the complex nature of its structure. Therefore, simplified models are required to undertake structure-function studies of processes that occur at the outer membrane/fluid int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::556d12b5f2e19e0ed38b8b8e45fa4122
https://doi.org/10.1016/bs.mie.2015.05.020

Self-Assembly of Protein Monolayers Engineered for Improved Monoclonal Immunoglobulin G Binding

Autor: Jeremy H. Lakey, Le, Brun, Ap, Deepan S. H. Shah, Dale Athey, Stephen A. Holt

Publikováno v: International Journal of Molecular Sciences
Volume 12
Issue 8
Pages 5157-5167
International Journal of Molecular Sciences, Vol 12, Iss 8, Pp 5157-5167 (2011)

Bacterial outer membrane proteins, along with a filling lipid molecule can be modified to form stable self-assembled monolayers on gold. The transmembrane domain of Escherichia coli outer membrane protein A has been engineered to create a scaffold pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7bda9e9a29156653354db07c1e03006

HIV and influenza fusion peptide interactions with (dis)ordered lipid bilayers: Understanding mechanisms and implications for antimicrobial and antiviral approaches.

Autor: Miłogrodzka I; Department of Chemical and Biological Engineering, Monash University, Clayton, Victoria, Australia; Australian Synchrotron, Clayton, Victoria, Australia., Le Brun AP; Australian Centre for Neutron Scattering, Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW, Australia., Banaszak Holl MM; Department of Chemical and Biological Engineering, Monash University, Clayton, Victoria, Australia; Department of Mechanical and Materials Engineering, University of Alabama at Birmingham, Birmingham, AL, USA; Division of Pulmonology, Allergy, and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., van 't Hag L; Department of Chemical and Biological Engineering, Monash University, Clayton, Victoria, Australia. Electronic address: Leonie.VantHag@monash.edu.

Publikováno v: Journal of colloid and interface science [J Colloid Interface Sci] 2024 Sep 15; Vol. 670, pp. 563-575. Date of Electronic Publication: 2024 May 11.