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PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice

Autor: Christou‐Kent, Marie, Kherraf, Zine‐Eddine, Amiri‐Yekta, Amir, Le Blévec, Emilie, Karaouzène, Thomas, Conne, Béatrice, Escoffier, Jessica, Assou, Said, Guttin, Audrey, Lambert, Emeline, Martinez, Guillaume, Boguenet, Magalie, Fourati Ben Mustapha, Selima, Cedrin Durnerin, Isabelle, Halouani, Lazhar, Marrakchi, Ouafi, Makni, Mounir, Latrous, Habib, Kharouf, Mahmoud, Coutton, Charles, Thierry‐Mieg, Nicolas, Nef, Serge, Bottari, Serge P, Zouari, Raoudha, Issartel, Jean Paul, Ray, Pierre F, Arnoult, Christophe

Publikováno v: EMBO Molecular Medicine, Vol. 10, No 5 (2018) pp. 459-66
EMBO Molecular Medicine
EMBO Molecular Medicine, 2018, 10 (5), pp.e8515. ⟨10.15252/emmm.201708515⟩
EMBO Molecular Medicine, Wiley Open Access, 2018, 10 (5), pp.e8515. ⟨10.15252/emmm.201708515⟩
EMBO Molecular Medicine, Vol 10, Iss 5, Pp n/a-n/a (2018)

International audience; The genetic causes of oocyte meiotic deficiency (OMD), a form of primary infertility characterised by the production of immature oocytes, remain largely unexplored. Using whole exome sequencing, we found that 26% of a cohort o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a81b2fc548206a292550a7a6c70cdd60
https://archive-ouverte.unige.ch/unige:109588

Slo3 K⁺ channel blocker clofilium extends bull and mouse sperm-fertilizing competence.

Autor: Nahed, Roland Abi, Martinez, Guillaume, Hograindleur, Jean Pascal, Le Blévec, Emilie, Camugli, Sabine, Le Boucher, Richard, Ray, Pierre F., Escoffier, Jessica, Schmitt, Eric, Arnoult, Christophe

Publikováno v: Reproduction; Dec2018, Vol. 156 Issue 6, p463-476, 14p

PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice.

Autor: Christou-Kent M; Genetics, Epigenetics and Therapies of Infertility, Institute for Advanced Biosciences, Inserm U1209, CNRS UMR 5309, Université Grenoble Alpes, Grenoble, France., Kherraf ZE; Genetics, Epigenetics and Therapies of Infertility, Institute for Advanced Biosciences, Inserm U1209, CNRS UMR 5309, Université Grenoble Alpes, Grenoble, France., Amiri-Yekta A; Genetics, Epigenetics and Therapies of Infertility, Institute for Advanced Biosciences, Inserm U1209, CNRS UMR 5309, Université Grenoble Alpes, Grenoble, France.; UM GI-DPI, CHU de Grenoble, Grenoble, France.; Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran., Le Blévec E; Genetics, Epigenetics and Therapies of Infertility, Institute for Advanced Biosciences, Inserm U1209, CNRS UMR 5309, Université Grenoble Alpes, Grenoble, France., Karaouzène T; Genetics, Epigenetics and Therapies of Infertility, Institute for Advanced Biosciences, Inserm U1209, CNRS UMR 5309, Université Grenoble Alpes, Grenoble, France., Conne B; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland., Escoffier J; Genetics, Epigenetics and Therapies of Infertility, Institute for Advanced Biosciences, Inserm U1209, CNRS UMR 5309, Université Grenoble Alpes, Grenoble, France., Assou S; IRMB, INSERM U1183, CHRU Montpellier, Université Montpellier, Montpellier, France., Guttin A; Grenoble Neuroscience Institute, INSERM 1216, Université Grenoble Alpes, Grenoble, France., Lambert E; Genetics, Epigenetics and Therapies of Infertility, Institute for Advanced Biosciences, Inserm U1209, CNRS UMR 5309, Université Grenoble Alpes, Grenoble, France., Martinez G; Genetics, Epigenetics and Therapies of Infertility, Institute for Advanced Biosciences, Inserm U1209, CNRS UMR 5309, Université Grenoble Alpes, Grenoble, France.; UM GI-DPI, CHU de Grenoble, Grenoble, France.; UM de Génétique Chromosomique, CHU de Grenoble, Grenoble, France., Boguenet M; Genetics, Epigenetics and Therapies of Infertility, Institute for Advanced Biosciences, Inserm U1209, CNRS UMR 5309, Université Grenoble Alpes, Grenoble, France., Fourati Ben Mustapha S; Polyclinique les Jasmins, Centre d'Aide Médicale à la Procréation, Centre Urbain Nord, Tunis, Tunisia., Cedrin Durnerin I; Service de Médecine de la Reproduction, Centre Hospitalier Universitaire Jean Verdier, Assistance Publique - Hôpitaux de Paris, Bondy, France., Halouani L; Polyclinique les Jasmins, Centre d'Aide Médicale à la Procréation, Centre Urbain Nord, Tunis, Tunisia., Marrakchi O; Polyclinique les Jasmins, Centre d'Aide Médicale à la Procréation, Centre Urbain Nord, Tunis, Tunisia., Makni M; Polyclinique les Jasmins, Centre d'Aide Médicale à la Procréation, Centre Urbain Nord, Tunis, Tunisia., Latrous H; Polyclinique les Jasmins, Centre d'Aide Médicale à la Procréation, Centre Urbain Nord, Tunis, Tunisia., Kharouf M; Polyclinique les Jasmins, Centre d'Aide Médicale à la Procréation, Centre Urbain Nord, Tunis, Tunisia., Coutton C; Genetics, Epigenetics and Therapies of Infertility, Institute for Advanced Biosciences, Inserm U1209, CNRS UMR 5309, Université Grenoble Alpes, Grenoble, France.; UM GI-DPI, CHU de Grenoble, Grenoble, France.; UM de Génétique Chromosomique, CHU de Grenoble, Grenoble, France., Thierry-Mieg N; Univ. Grenoble Alpes/CNRS, TIMC-IMAG CNRS UMR 5525, Grenoble, France., Nef S; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland., Bottari SP; Genetics, Epigenetics and Therapies of Infertility, Institute for Advanced Biosciences, Inserm U1209, CNRS UMR 5309, Université Grenoble Alpes, Grenoble, France., Zouari R; Polyclinique les Jasmins, Centre d'Aide Médicale à la Procréation, Centre Urbain Nord, Tunis, Tunisia., Issartel JP; Grenoble Neuroscience Institute, INSERM 1216, Université Grenoble Alpes, Grenoble, France., Ray PF; Genetics, Epigenetics and Therapies of Infertility, Institute for Advanced Biosciences, Inserm U1209, CNRS UMR 5309, Université Grenoble Alpes, Grenoble, France.; UM GI-DPI, CHU de Grenoble, Grenoble, France., Arnoult C; Genetics, Epigenetics and Therapies of Infertility, Institute for Advanced Biosciences, Inserm U1209, CNRS UMR 5309, Université Grenoble Alpes, Grenoble, France christophe.arnoult@univ-grenoble-alpes.fr.

Publikováno v: EMBO molecular medicine [EMBO Mol Med] 2018 May; Vol. 10 (5).