Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Le Anh, Luong"'
Autor:
Ingrid Gomez, Ben Ward, Celine Souilhol, Chiara Recarti, Mark Ariaans, Jessica Johnston, Amanda Burnett, Marwa Mahmoud, Le Anh Luong, Laura West, Merete Long, Sion Parry, Rachel Woods, Carl Hulston, Birke Benedikter, Chiara Niespolo, Rohit Bazaz, Sheila Francis, Endre Kiss-Toth, Marc van Zandvoort, Andreas Schober, Paul Hellewell, Paul C. Evans, Victoria Ridger
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
The role of neutrophils in the development of atherosclerosis has long been an enigma, with few neutrophils detected within the plaque. Here, the authors show that microvesicles released from neutrophils increase vascular inflammation and enhance ath
Externí odkaz:
https://doaj.org/article/56d869ba2dc54e5c8b181fd48b5df87b
Autor:
Ana M. Metelo, Agnieszka Jozwik, Le Anh Luong, Delaney Dominey-Foy, Charlotte Graham, Charlotte Attwood, Shafqat Inam, Alan Dunlop, Katy Sanchez, Kirsty Cuthill, Carmel Rice, Matthew Streetly, Trevor Bentley, Bijan Boldajipour, Cesar Sommer, Barbra Sasu, Reuben Benjamin
Publikováno v:
Cancer Research Communications. 2:158-171
Multiple myeloma remains an incurable plasma cell malignancy despite the rapidly evolving treatment landscape. Chimeric antigen receptor T cells targeted against BCMA have recently shown great promise in relapsed refractory multiple myeloma; however,
Autor:
Tayyab Adeel Afzal, Le Anh Luong, Dan Chen, Cheng Zhang, Feng Yang, Qishan Chen, Weiwei An, Edmund Wilkes, Kenta Yashiro, Pedro R. Cutillas, Li Zhang, Qingzhong Xiao
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 12 (2016)
BackgroundMicroRNA miR‐214 has been implicated in many biological cellular functions, but the impact of miR‐214 and its target genes on vascular smooth muscle cell (VSMC) proliferation, migration, and neointima smooth muscle cell hyperplasia is u
Externí odkaz:
https://doaj.org/article/c097f5e8833a422f8ca7136bf9b42aa0
Autor:
Victoria Ridger, Chiara Recarti, Marwa Mahmoud, Andreas Schober, Amanda Burnett, Merete Long, Ingrid Gomez, Ben Ward, Jessica Johnston, Marc A. M. J. van Zandvoort, Sheila E. Francis, Siôn A Parry, Paul G. Hellewell, Endre Kiss-Toth, Mark P. Ariaans, Celine Souilhol, Le Anh Luong, Rohit Bazaz, Laura West, Rachel M Woods, Birke J. Benedikter, Chiara Niespolo, Paul C. Evans, Carl J. Hulston
Publikováno v:
Nature Communications
Nature Communications, 11(1):214. Nature Publishing Group
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications, 11(1):214. Nature Publishing Group
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Neutrophils are implicated in the pathogenesis of atherosclerosis but are seldom detected in atherosclerotic plaques. We investigated whether neutrophil-derived microvesicles may influence arterial pathophysiology. Here we report that levels of circu
Autor:
Li Zhang, Qingzhong Xiao, Tayyab Adeel Afzal, Qishan Chen, Feng Yang, Le Anh Luong, Eithne Margaret Maguire, Weiwei An, Mei Yang, Shiping He
Publikováno v:
Circulation
Supplemental Digital Content is available in the text.
Background: MicroRNA-22 (miR-22) has recently been reported to play a regulatory role during vascular smooth muscle cell (VSMC) differentiation from stem cells, but little is known about its
Background: MicroRNA-22 (miR-22) has recently been reported to play a regulatory role during vascular smooth muscle cell (VSMC) differentiation from stem cells, but little is known about its
Akademický článek
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Autor:
Dan Chen, Qingzhong Xiao, Jianhua Zhu, Eithne Margaret Maguire, Guanmei Wen, Weiwei An, Qishan Chen, Feng Yang, Le Anh Luong, Qingbo Xu, Li Zhang, Bin Dai, Cheng Zhang, Mei Yang
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37:2182-2194
Objective— hnRNPA1 (heterogeneous nuclear ribonucleoprotein A1) plays a variety of roles in gene expression. However, little is known about the functional involvement of hnRNPA1 in vascular smooth muscle cell (VSMC) function and neointima hyperplas
Autor:
Chiara Recarti, Le Anh Luong, Amanda Burnett, Celine Souilhol, Ben Ward, Endre Kiss-Toth, Jessica Johnston, Victoria Ridger, Merete Long, Marwa Mahmoud, Sheila E. Francis, Andreas Schober, Siôn A Parry, Paul Hellewell, Marc A. M. J. van Zandvoort, Mark P. Ariaans, Carl J. Hulston, Birke J. Benedikter, Ingrid Gomez, Rachel M Woods, Laura West, Paul C. Evans, Rohit Bazaz
Neutrophils have been implicated in the pathogenesis of atherosclerosis, a lipid-driven disease of arteries, but they are seldom found in atherosclerotic plaques. To resolve this longstanding paradox, we investigated whether neutrophil-derived microv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809f542794cdfee829847af7dcd9abb4
Publikováno v:
Journal of Biological Chemistry. 290:19158-19172
Matrix metalloproteinase-8 (MMP8) has been shown to influence various cellular functions. As monocytes and macrophages (Mφ) express MMP8, we investigated if MMP8 played a role in macrophage differentiation and polarization. MMP8 expression was signi
Autor:
Hanqing, Zhao, Guanmei, Wen, Guammei, Wen, Yuan, Huang, Xiaotian, Yu, Qishan, Chen, Tayyab Adeel, Afzal, Le Anh, Luong, Jianhua, Zhu, Shu, Ye, Ye, Shu, Li, Zhang, Qingzhong, Xiao
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35:918-929
Objective— In this study, we attempted to uncover the functional impact of microRNA-22 (miR-22) and its target gene in smooth muscle cell (SMC) differentiation and delineate the molecular mechanism involved. Approach and Results— miR-22 was found