BDNF augmentation reverses cranial radiation therapy-induced cognitive decline and neurodegenerative consequences.

Autor: El-Khatib SM; Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, USA., Vagadia AR; Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, USA., Le ACD; Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, USA., Baulch JE; Department of Radiation Oncology, School of Medicine, University of California, Irvine, USA., Ng DQ; Department of Clinical Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, University of California, Irvine, USA., Du M; Center for Neural Circuit Mapping, School of Medicine, University of California, Irvine, USA., Johnston KG; Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, USA.; Center for Neural Circuit Mapping, School of Medicine, University of California, Irvine, USA., Tan Z; Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, USA.; Center for Neural Circuit Mapping, School of Medicine, University of California, Irvine, USA., Xu X; Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, USA.; Center for Neural Circuit Mapping, School of Medicine, University of California, Irvine, USA., Chan A; Department of Clinical Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, University of California, Irvine, USA. a.chan@uci.edu.; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University of California, Irvine, USA. a.chan@uci.edu., Acharya MM; Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, USA. macharya@uci.edu.; Department of Radiation Oncology, School of Medicine, University of California, Irvine, USA. macharya@uci.edu.

Publikováno v: Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Dec 18; Vol. 12 (1), pp. 190. Date of Electronic Publication: 2024 Dec 18.

BDNF Augmentation Using Riluzole Reverses Doxorubicin-Induced Decline in Cognitive Function and Neurogenesis.

Autor: Usmani MT; Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, CA, USA., Krattli RP Jr; Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, CA, USA., El-Khatib SM; Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, CA, USA., Le ACD; Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, CA, USA., Smith SM; Department of Radiation Oncology, School of Medicine, University of California, Irvine, CA, USA., Baulch JE; Department of Radiation Oncology, School of Medicine, University of California, Irvine, CA, USA., Ng DQ; Department of Clinical Pharmacy Practice, School of Pharmacy & Pharmaceutical Sciences, University of California, Irvine, CA, USA.; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University of California, Irvine, CA, USA., Acharya MM; Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, CA, USA. macharya@uci.edu.; Department of Radiation Oncology, School of Medicine, University of California, Irvine, CA, USA. macharya@uci.edu., Chan A; Department of Clinical Pharmacy Practice, School of Pharmacy & Pharmaceutical Sciences, University of California, Irvine, CA, USA. a.chan@uci.edu.; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University of California, Irvine, CA, USA. a.chan@uci.edu.

Publikováno v: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics [Neurotherapeutics] 2023 Apr; Vol. 20 (3), pp. 838-852. Date of Electronic Publication: 2023 Jan 31.