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Tolfenpyrad Derivatives Exhibit Potent Francisella -Specific Antibacterial Activity without Toxicity to Mammalian Cells In Vitro .

Autor: Khalid N; Department of Infectious Diseases & Immunology, University of Florida, Gainesville, Florida 32608, United States., Adams N; Department of Infectious Diseases & Immunology, University of Florida, Gainesville, Florida 32608, United States., Cunha F; Department of Large Animal Clinical Sciences, University of Florida, Gainesville, Florida 32608, United States., Taki AC; Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Science, The University of Melbourne, Parkville, Melbourne, Victoria 3010, Australia., Le TG; Department of Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Melbourne, Victoria 3052, Australia., Baell JB; Department of Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Melbourne, Victoria 3052, Australia., Heine HS; Institute for Therapeutic Innovation, University of Florida, Orlando, Florida 32827, United States., Gasser RB; Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Science, The University of Melbourne, Parkville, Melbourne, Victoria 3010, Australia., Eshraghi A; Department of Infectious Diseases & Immunology, University of Florida, Gainesville, Florida 32608, United States.; Emerging Pathogens Institute, University of Florida, Gainesville, Florida 32610, United States.; Department of Oral Biology, University of Florida, Gainesville, Florida 32610, United States.

Publikováno v: ACS infectious diseases [ACS Infect Dis] 2024 Nov 08; Vol. 10 (11), pp. 3902-3914. Date of Electronic Publication: 2024 Oct 02.

Hemolytic Performance in Two Generations of the Sputnik Left Ventricular Assist Device: A Combined Numerical and Experimental Study.

Autor: Romanova AN; Institute of Biomedical Systems, National Research University of Electronic Technology, 124498 Zelenograd, Moscow, Russia., Pugovkin AA; Institute of Biomedical Systems, National Research University of Electronic Technology, 124498 Zelenograd, Moscow, Russia.; Center for Digital Biodesign and Personalized Healthcare, I. M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia., Denisov MV; Institute of Biomedical Systems, National Research University of Electronic Technology, 124498 Zelenograd, Moscow, Russia., Ephimov IA; Institute of Biomedical Systems, National Research University of Electronic Technology, 124498 Zelenograd, Moscow, Russia., Gusev DV; Institute of Biomedical Systems, National Research University of Electronic Technology, 124498 Zelenograd, Moscow, Russia., Walter M; Medical Information Technology, Helmholtz Institute of Biomedical Engineering, RWTH Aachen University, 52074 Aachen, Germany., Groth T; Center for Digital Biodesign and Personalized Healthcare, I. M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Department Biomedical Materials, Institute of Pharmacy, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany., Bockeria OL; Bakulev Scientific Center for Cardiovascular Surgery, 121552 Moscow, Russia., Le TG; Bakulev Scientific Center for Cardiovascular Surgery, 121552 Moscow, Russia., Satyukova AS; Bakulev Scientific Center for Cardiovascular Surgery, 121552 Moscow, Russia., Selishchev SV; Institute of Biomedical Systems, National Research University of Electronic Technology, 124498 Zelenograd, Moscow, Russia., Telyshev DV; Institute of Biomedical Systems, National Research University of Electronic Technology, 124498 Zelenograd, Moscow, Russia.; Center for Digital Biodesign and Personalized Healthcare, I. M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.

Publikováno v: Journal of functional biomaterials [J Funct Biomater] 2022 Jan 12; Vol. 13 (1). Date of Electronic Publication: 2022 Jan 12.

1-Methyl-1 H -pyrazole-5-carboxamide Derivatives Exhibit Unexpected Acute Mammalian Toxicity.

Autor: Preston S; School of Health and Life Sciences, Federation University, Ballarat, Victoria 3353, Australia., Garcia-Bustos J; Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia., Hall LG; Metabolic Research Unit, Metabolic Reprogramming Laboratory, School of Medicine, Faculty of Health, Deakin University, Waurn Ponds, Victoria 3216, Australia., Martin SD; Metabolic Research Unit, Metabolic Reprogramming Laboratory, School of Medicine, Faculty of Health, Deakin University, Waurn Ponds, Victoria 3216, Australia., Le TG; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Kundu A; TCG Lifesciences Private Limited, Block BN, Plot 7, Salt-lake Electronics Complex, Sector V, Kolkata 700091, West Bengal, India., Ghoshal A; TCG Lifesciences Private Limited, Block BN, Plot 7, Salt-lake Electronics Complex, Sector V, Kolkata 700091, West Bengal, India., Nguyen NH; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Jiao Y; Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia., Ruan B; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Xue L; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Huang F; School of Pharmaceutical Sciences, Nanjing Tech University, No. 30 South Puzhu Road, Nanjing 211816, People's Republic of China., Chang BCH; Yourgene, Bioscience, Taipei 23863, Taiwan., McGee SL; Metabolic Research Unit, Metabolic Reprogramming Laboratory, School of Medicine, Faculty of Health, Deakin University, Waurn Ponds, Victoria 3216, Australia., Wells TNC; Medicines for Malaria Venture, 1215 Geneva, Switzerland., Palmer MJ; Medicines for Malaria Venture, 1215 Geneva, Switzerland., Jabbar A; Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia., Gasser RB; Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia., Baell JB; School of Pharmaceutical Sciences, Nanjing Tech University, No. 30 South Puzhu Road, Nanjing 211816, People's Republic of China.; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2021 Jan 14; Vol. 64 (1), pp. 840-844. Date of Electronic Publication: 2020 Dec 22.