Zobrazeno 1 - 10
of 717
pro vyhledávání: '"Lcn2"'
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Chronic obstructive pulmonary disease (COPD) is a complex respiratory condition influenced by environmental and genetic factors. Using next-generation sequencing, we aimed to identify dysregulated genes and potential therapeutic t
Externí odkaz:
https://doaj.org/article/cc8b35d26734426bb51b6561155ebe69
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 5599-5618 (2024)
Yuya Wen,1 Chenling Zhao,1 Jie Chen,1 Liwei Tian,1 Bojin Wu,1 Wenting Xie,1 Ting Dong1,2 1Department of Neurology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230031, People’s Republic of China; 2Key Laboratory of
Externí odkaz:
https://doaj.org/article/06fab4be0d2440e28d6d3a383b800a4f
Autor:
Kaniha Sivakumar, Usha Subbiah
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Lipocalin-2 (LCN2), a neutrophil gelatinase-associated protein, plays an important role in iron homeostasis, infection, and inflammation. Polymorphism in the LCN2 gene is linked to various diseases such as cardiovascular disease,
Externí odkaz:
https://doaj.org/article/f445c1ea88b34864907279eaa2984f08
Autor:
Mohammadreza Kosari, Afsaneh Asgari Taei, Andis Klegeris, Sevim Soleimani, Arian Tavasol, Kimia Jazi, Kimia Eyvani, Ashkan Bahrami, Zahra Farrokhi, Farnoosh Vosough, Faraz Rahmani Khajeh, Saleh Behzadi, Zohreh Zamani
Publikováno v:
Caspian Journal of Neurological Sciences, Vol 10, Iss 3, Pp 151-168 (2024)
Background: Parkinson disease (PD) is a prevalent neurodegenerative disorder affecting dopaminergic neurons in the substantia nigra (SN). Neuroinflammation has a vital role in PD pathophysiology. Objectives: This study assesses whether the neuroinfla
Externí odkaz:
https://doaj.org/article/ee898c1994754acd8687184871d600e5
Autor:
Xinxia Zhu, Brennan Olson, Dove Keith, Mason A Norgard, Peter R Levasseur, Parham Diba, Sara Protzek, Ju Li, Xiaolin Li, Tetiana Korzun, Ariana L Sattler, Abigail C Buenafe, Aaron J Grossberg, Daniel L Marks
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102129- (2024)
Background: The prognosis of pancreatic ductal adenocarcinomas (PDAC) remains very poor, emphasizing the critical importance of early detection, where biomarkers offer unique potential. Although growth differentiation factor 15 (GDF15) and Lipocalin
Externí odkaz:
https://doaj.org/article/c0b34edd40a14527bc1bb7e7e9b8b454
Autor:
Qing Li, Zicheng Huang, Hongsheng Yang, Jian Tang, Tao Zuo, Qingfan Yang, Zhaopeng Huang, Qin Guo, Miao Li, Xiang Gao, Kang Chao
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Variations exist in the response of patients with Crohn’s disease (CD) to ustekinumab (UST) treatment, but the underlying cause remains unknown. Our objective was to investigate the involvement of immune cells and identify poten
Externí odkaz:
https://doaj.org/article/041d115570fb45daa5a907cfbe2bf47f
Autor:
Chunyang Fan, Wei Wang, Zilin Yu, Jiale Wang, Wei Xu, Zhongwei Ji, Wei He, Di Hua, Wentao Wang, Linye Yao, Yongkang Deng, Dechun Geng, Xiexing Wu, Haiqing Mao
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Intervertebral disc degeneration (IVDD) is the primary factor contributing to low back pain (LBP). Unlike elderly patients, many young IVDD patients usually have a history of trauma or long-term abnormal stress, which may lead to local infla
Externí odkaz:
https://doaj.org/article/3fa3c22bfe5844cfb73a1968b14d6348
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Ferroptosis is an iron-dependent form of cell death, which finally culminates in lipid peroxidation and membrane damage. During the past decade, the interest in ferroptosis increased substantially and various regulatory components were discovered. Th
Externí odkaz:
https://doaj.org/article/ab6f33bf92b249c7a681cc9fb5c1f723
Autor:
Quntao Huang, Junhong Xing, Guoli Li, Mengting Liu, Mengtian Gao, Jingwen Wang, Fang Tang, Jianluan Ren, Chengzhu Zhao, Xinru Wang, Xinyu Zhou, Haodong Luo, Youli Yu, Dexin Zeng, Jianjun Dai, Feng Xue
Publikováno v:
mSystems, Vol 9, Iss 8 (2024)
ABSTRACT Infection with Mycobacterium bovis precipitates a spectrum of pathologies in bovines, notably necrotic pneumonia, mastitis, and arthritis, impinging upon the health and nutritional assimilation of these animals. A pivotal factor, lipocalin 2
Externí odkaz:
https://doaj.org/article/0411464b660a4cecb0790e8a6d7a3426
Publikováno v:
Breast Cancer: Targets and Therapy, Vol Volume 16, Pp 1-13 (2024)
Suheyla Ekemen,1,2 Ebru Bilir,3 Hagar Elsayed Akram Soultan,3 Sadia Zafar,3 Figen Demir,4 Babek Tabandeh,5 Sadik Toprak,6 Ozlem Yapicier,7 Cevayir Coban2,8,9 1Vocational School of Health Services, Acibadem University, Istanbul, Turkey; 2Division of M
Externí odkaz:
https://doaj.org/article/95c1f39953ba4d5e89a822ce00ed5b98