Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Lb, Grochow"'
Autor:
Lb, Grochow, Ek, Rowinsky, Johnson R, Ludeman S, Scott Kaufmann, Fl, Mccabe, Br, Smith, Hurowitz L, DeLisa A, Rc, Donehower
Publikováno v:
Europe PubMed Central
Topotecan, a semisynthetic water-soluble analog of camptothecin, is the first topoisomerase I-directed drug to enter clinical trial in the United States in over 20 yr. In this study, 30-min infusions of topotecan were administered daily for 5 days ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::55834875de21d8bcaba88a44f506ce5e
https://pubmed.ncbi.nlm.nih.gov/1358575
https://pubmed.ncbi.nlm.nih.gov/1358575
Publikováno v:
Blood. 75(8)
Children receive busulfan orally as part of myeloablative therapy before bone marrow transplantation for malignant and nonmalignant conditions. Children have been reported to have a low incidence of severe toxicity and significant rates of failure to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40010ea0b8915dfd633bf8a41529e2a8
https://pubmed.ncbi.nlm.nih.gov/2328321
https://pubmed.ncbi.nlm.nih.gov/2328321
Autor:
Aa, Adjei, Ii, Budihardjo, Ek, Rowinsky, Tj, Kottke, Pa, Svingen, Ca, Buckwalter, Lb, Grochow, Rc, Donehower, Scott Kaufmann
Publikováno v:
Europe PubMed Central
Pyrazoloacridine (PA), an acridine congener that has shown selective toxicity in solid tumor cells, full activity against noncycling and hypoxic cells, and promising activity in a recent Phase I trial, is currently undergoing Phase II testing as a so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f1ea332ef7c5dcc7a56fa6fb696bd103
http://europepmc.org/abstract/med/9815747
http://europepmc.org/abstract/med/9815747
Publikováno v:
Europe PubMed Central
Topotecan (TPT, 9-dimethylaminomethyl-10-hydroxycamptothecin) is the first topoisomerase I-directed cytotoxic agent to enter clinical trials in the United States in two decades. The effect of P-glycoprotein (Pgp) overexpression on TPT cytotoxicity wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4565cd1fd6b752734de5432605b14005
http://europepmc.org/abstract/med/1348448
http://europepmc.org/abstract/med/1348448
Autor:
Baker SD; Division of Experimental Therapeutics, The Sydney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21237, USA. sdbaker@jhmi.edu, Verweij J, Rowinsky EK, Donehower RC, Schellens JH, Grochow LB, Sparreboom A
Publikováno v:
Journal of the National Cancer Institute [J Natl Cancer Inst] 2002 Dec 18; Vol. 94 (24), pp. 1883-8.
Autor:
Gore SD; The Johns Hopkins Oncology Center, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Maryland 21231, USA. Steven.Gore@jhu.edu, Weng LJ, Figg WD, Zhai S, Donehower RC, Dover G, Grever MR, Griffin C, Grochow LB, Hawkins A, Burks K, Zabelena Y, Miller CB
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2002 Apr; Vol. 8 (4), pp. 963-70.
Autor:
Azuma R; Pharmacokinetics Research Laboratory, Taiho Pharmaceutical Co, Ltd, Tokushima, Japan. ryu-azuma@taiho.co.jp, Saeki M, Yamamoto Y, Hagiwara Y, Grochow LB, Donehower RC
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2002 Jan; Vol. 32 (1), pp. 63-72.
Autor:
Grochow LB; Investigational Drug Branch, National Cancer Institute, Rockville, Maryland, USA.
Publikováno v:
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation [Biol Blood Marrow Transplant] 2002; Vol. 8 (9), pp. 465-7.
Autor:
Heath EI; Johns Hopkins Oncology Center, Baltimore, MD 21231, USA. heathel@jhmi.edu, O'Reilly S, Humphrey R, Sundaresan P, Donehower RC, Sartorius S, Kennedy MJ, Armstrong DK, Carducci MA, Sorensen JM, Kumor K, Kennedy S, Grochow LB
Publikováno v:
Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2001 Oct; Vol. 48 (4), pp. 269-74.
Autor:
Carducci MA; Division of Medical Oncology, The Johns Hopkins Oncology Center, 1 M88 Bunting-Blaustein Cancer Research Building, 1650 Orleans Street, Baltimore, MD 21231, USA. carducci@jhmi.edu, Gilbert J, Bowling MK, Noe D, Eisenberger MA, Sinibaldi V, Zabelina Y, Chen TL, Grochow LB, Donehower RC
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2001 Oct; Vol. 7 (10), pp. 3047-55.