Zobrazeno 1 - 10
of 3 777
pro vyhledávání: '"Lazzeri P"'
The assembly of proteins in membranes plays a key role in many crucial cellular pathways. Despite their importance, characterizing transmembrane assembly remains challenging for experiments and simulations. Equilibrium molecular dynamics simulations
Externí odkaz:
http://arxiv.org/abs/2408.01407
We present a computational scheme for predicting the ligands that bind to a pocket of known structure. It is based on the generation of a general abstract representation of the molecules, which is invariant to rotations, translations and permutations
Externí odkaz:
http://arxiv.org/abs/2405.04916
Molecular dynamics is a powerful tool for studying the thermodynamics and kinetics of complex molecular events. However, these simulations can rarely sample the required time scales in practice. Transition path sampling overcomes this limitation by c
Externí odkaz:
http://arxiv.org/abs/2307.11240
Autor:
Isaac Lazzeri, Benjamin Gernot Spiegl, Samantha O. Hasenleithner, Michael R. Speicher, Martin Kircher
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3163-3174 (2024)
Motivation: The analysis of circulating cell-free DNA (cfDNA) holds immense promise as a non-invasive diagnostic tool across various human conditions. However, extracting biological insights from cfDNA fragments entails navigating complex and diverse
Externí odkaz:
https://doaj.org/article/27b524cbd63e445aa72d146cd881ec61
Autor:
Nuhara Vargiu, Aurora Belfanti, Michela Roberti, Serena Trentin, Camilla Ferrara, Manuela Tosti, Marco Lazzeri, Giancarlo Giupponi, Andreas Conca
Publikováno v:
Annals of General Psychiatry, Vol 23, Iss 1, Pp 1-4 (2024)
Abstract General Practitioners (GPs) play a key role in the early detection and management of depression and in preventing suicide risk. They are often the first healthcare professionals that people in crisis contact. However, their effectiveness can
Externí odkaz:
https://doaj.org/article/5c8a46e1262e4c3488e5c3693873bbe2
Publikováno v:
Macromol, Vol 4, Iss 2, Pp 401-419 (2024)
The present chapter focuses on the recyclability of both renewable and biodegradable plastics, considering the recovery of matter (mechanical or chemical recycling) from the polymeric materials currently most diffused on the market. Biobased and comp
Externí odkaz:
https://doaj.org/article/9a391ea6de994a4a8c6adf1f22119078
Autor:
Davide Tarello, Francesca Giogà, Andrea Lauterio, Chiara Becchetti, Giovanni Perricone, Giorgio Santi, Monica Ragazzi, Gianpaola Monti, Marta Lazzeri
Publikováno v:
Monaldi Archives for Chest Disease (2024)
Acute-on-chronic liver failure (ACLF) is a severe clinical condition for which liver transplantation (LT) is the only curative option. Due to the recipients' generally poor pre-operative clinical conditions and extensive surgery, post-LT respiratory
Externí odkaz:
https://doaj.org/article/4313bb7a81e84354bf4baa7a426795bb
Autor:
Vanessa Lozano, Flavio Marzialetti, Alicia Teresa Rosario Acosta, Iduna Arduini, Gianluigi Bacchetta, Gianniantonio Domina, Valentina Lucia Astrid Laface, Valerio Lazzeri, Chiara Montagnani, Carmelo Maria Musarella, Gianluca Nicolella, Lina Podda, Giovanni Spampinato, Gianmarco Tavilla, Giuseppe Brundu
Publikováno v:
Ecological Indicators, Vol 166, Iss , Pp 112279- (2024)
Given the high number of non-native plants that are being introduced worldwide and the time required to process formal pest risk analyses, a framework for the prioritization of management actions is urgently required. We therefore propose a framework
Externí odkaz:
https://doaj.org/article/78b14e265d284097bb39c15189984dd4
Autor:
Adam F. Smith, Katharina Kasper, Lorenzo Lazzeri, Michael Schulte, Svitlana Kudrenko, Elise Say-Sallaz, Marcin Churski, Dmitry Shamovich, Serhii Obrizan, Serhii Domashevsky, Kateryna Korepanova, Andriy-Taras Bashta, Rostyslav Zhuravchak, Martin Gahbauer, Bartosz Pirga, Viktar Fenchuk, Josip Kusak, Francesco Ferretti, Dries P.J. Kuijper, Krzysztof Schmidt, Marco Heurich
Publikováno v:
Global Ecology and Conservation, Vol 53, Iss , Pp e02985- (2024)
Wildlife in the Anthropocene is increasingly spatially and temporally constrained by lethal and non-lethal human disturbance. For large carnivores with extensive space requirements, like wolves and Eurasian lynx, avoiding human disturbance in Europea
Externí odkaz:
https://doaj.org/article/0affec6ee4af4cf3b634934cc4fd3871
Publikováno v:
Kidney & Blood Pressure Research, Vol 49, Iss 1, Pp 258-265 (2024)
Background: Chronic kidney disease affects 10% of the world population, and it is associated with progression to end-stage kidney disease and increased morbidity and mortality. The advent of multi-omics technologies has expanded our knowledge on the
Externí odkaz:
https://doaj.org/article/280452f276f34d03aec72eb0e118cc5e