A fur plucking model to study herpes simplex virus reactivation and recurrent disease.

Autor: Philip DT; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Goins NM; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Lazear HM; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Publikováno v: MSphere [mSphere] 2024 Oct 29; Vol. 9 (10), pp. e0078323. Date of Electronic Publication: 2024 Oct 09.

Interferon lambda restricts herpes simplex virus skin disease by suppressing neutrophil-mediated pathology.

Autor: Philip DT; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Goins NM; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Catanzaro NJ; Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Misumi I; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Whitmire JK; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Atkins HM; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Lazear HM; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Publikováno v: MBio [mBio] 2024 Apr 10; Vol. 15 (4), pp. e0262323. Date of Electronic Publication: 2024 Mar 01.

Interferon lambda restricts herpes simplex virus skin disease by suppressing neutrophil-mediated pathology.

Autor: Philip DT; Department of Microbiology & Immunology, University of North Carolina at Chapel Hill., Goins NM; Department of Microbiology & Immunology, University of North Carolina at Chapel Hill., Catanzaro NJ; Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill., Misumi I; Department of Genetics, University of North Carolina at Chapel Hill., Whitmire JK; Department of Microbiology & Immunology, University of North Carolina at Chapel Hill.; Department of Genetics, University of North Carolina at Chapel Hill., Atkins HM; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill., Lazear HM; Department of Microbiology & Immunology, University of North Carolina at Chapel Hill.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Sep 14. Date of Electronic Publication: 2023 Sep 14.

Lifetime of ground conformational state determines the activity of structured RNA.

Autor: Thompson RD; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Carbaugh DL; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Nielsen JR; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Witt CM; Department of Biophysics and Chemistry, University of Michigan, Ann Arbor, MI, USA., Meganck RM; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Rangadurai A; Department of Biochemistry, Duke University, Durham, NC, USA., Zhao B; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Bonin JP; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Nicely NI; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Marzluff WF; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Frank AT; Department of Biophysics and Chemistry, University of Michigan, Ann Arbor, MI, USA., Lazear HM; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Zhang Q; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; RNA Discovery Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Publikováno v: Research square [Res Sq] 2023 May 26. Date of Electronic Publication: 2023 May 26.

A Zika virus-specific IgM elicited in pregnancy exhibits ultrapotent neutralization.

Autor: Singh T; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA 94709, USA., Hwang KK; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Miller AS; Department of Biological Sciences, Purdue Institute of Inflammation, Immunology, and Infectious Disease, Purdue University, West Lafayette, IN 47907, USA., Jones RL; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Lopez CA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Dulson SJ; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Giuberti C; Núcleo de Doenças Infecciosas-Universidade Federal do Espίrito Santo, Vitoria, Espίrito Santo 29075-910, Brazil., Gladden MA; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Miller I; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Pediatrics, Weill Cornell Medicine, New York City, NY 10065, USA., Webster HS; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Eudailey JA; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Pediatrics, Weill Cornell Medicine, New York City, NY 10065, USA., Luo K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Von Holle T; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Edwards RJ; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Valencia S; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Burgomaster KE; Viral Pathogenesis Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 USA., Zhang S; Duke-National University of Singapore Medical School, 169857, Singapore., Mangold JF; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Tu JJ; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Dennis M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Alam SM; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Premkumar L; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Dietze R; Núcleo de Doenças Infecciosas-Universidade Federal do Espίrito Santo, Vitoria, Espίrito Santo 29075-910, Brazil; Global Health & Tropical Medicine, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon 1349-008, Portugal., Pierson TC; Viral Pathogenesis Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 USA., Ooi EE; Duke-National University of Singapore Medical School, 169857, Singapore., Lazear HM; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Kuhn RJ; Department of Biological Sciences, Purdue Institute of Inflammation, Immunology, and Infectious Disease, Purdue University, West Lafayette, IN 47907, USA., Permar SR; Department of Pediatrics, Weill Cornell Medicine, New York City, NY 10065, USA. Electronic address: sap4017@med.cornell.edu., Bonsignori M; Translational Immunobiology Unit, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: mattia.bonsignori@nih.gov.

Publikováno v: Cell [Cell] 2022 Dec 08; Vol. 185 (25), pp. 4826-4840.e17. Date of Electronic Publication: 2022 Nov 18.