Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Lazarowski, E.R."'
Autor:
Stephan, H., Alexis, N.E., Morton, L.C., O'Neal, W.K., Ceppe, A., Donaldson, S., Lazarowski, E.R., Anderson, W.H., Button, B., Dang, H., Boucher, R.C., van Heusden, C.
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology 318(2020)2, L356-L365
Airway surface dehydration is a pathological feature of cystic fibrosis (CF) lung disease. 20 CF is caused by mutations in the CF transmembrane conductance regulator (CFTR), a cyclic 21 AMP-regulated Cl- channel controlled in part by the adenosine A2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c2ba0ae61299573c2834a5a856eeae8
https://www.hzdr.de/publications/Publ-29983-1
https://www.hzdr.de/publications/Publ-29983-1
Aldehydes in cigarette smoke (CS) impair mitochondrial function and reduce ciliary beat frequency (CBF), leading to diminished mucociliary clearance (MCC). However, the effects of aldehyde e-cigarette flavorings on CBF are unknown. The purpose of thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7351ca6bb7becccc850b38aa7e3a15cc
Autor:
Ceppe, A., Alexis, N.E., Davis, C.W., Henderson, A.G., Kesimer, M., Peden, D.B., Almond, M., Anderson, W.H., Boucher, R.C., Lazarowski, E.R., Button, B., Qaqish, B., Coakley, R.D., Fuller, F.
Mucus hydration is important in mucus clearance and lung health. This study sought to test the relative utility of spontaneous sputum (SS) versus the reasonably noninvasive induced sputum (IS) samples for measurement of mucus hydration. SS and IS sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7acb287d57bb691e341b1c8249d54c73
Autor:
Jones, L., Lazarowski, E.R., Trejo, J.A., Boucher, R.C., Kreda, S., O'Neal, W., Seminario-Vidal, L.
Extracellular ATP controls key aspects of lung function via activation of epithelial cell purinergic receptors, but how ATP is released from cells remains poorly understood. To identify mechanistic components upstream of ATP release, we examined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::894b081037ba8c40047447309ff4059b
Mechanical ventilation alters airway nucleotides and purinoceptors in lung and extrapulmonary organs
Autor:
Boucher, R.C., Douillet, C.D., Robinson III, W.P., Lazarowski, E.R., Zarzaur, B.L., Rich, P.B.
Extracellular nucleotides are stress-responsive ligands that mediate a variety of cellular processes via purinoceptors. We hypothesized that mechanical ventilation (MV) would alter the extracellular adenyl-nucleotide profile and purinoceptor expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a710125b8bf3a41413a3dbe6d3ab6139
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To test for the role of the P2Y2 receptor(P2Y2-R) in the regulation of nucleotide-promoted Ca2+ signaling in the lung, we generated P2Y2-R- deficient (P2Y2-R(-/-)) mice and measured intracellular Ca2+(i) responses (ΔCa2+(i)) to nucleotides in cultur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f2e8e43e960a73b5d1ffdc069c06c8e
The cystic fibrosis (CF) transmembrane regulator (CFTR) is a cyclic AMP- dependent Cl- channel that is defective in CF cells. It has been hypothesized that CFTR exhibits an ATP release function that controls the airway surface ATP concentrations. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02cc63c46fbba80bbb529a55c1a088a3
Akademický článek
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