Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Lazaro Lorenzo"'
Autor:
Assiya El Kettani, Hind Ouair, Farida Marnissi, Jalila El Bakkouri, Rémi Chevalier, Lazaro Lorenzo, Halima Kholaiq, Vivien Béziat, Emmanuelle Jouanguy, Jean-Laurent Casanova, Ahmed Aziz Bousfiha
Publikováno v:
Viruses, Vol 16, Iss 9, p 1415 (2024)
Epidermodysplasia verruciformis (EV) is a rare genodermatosis caused by β-human papillomaviruses (HPV) in immunodeficient patients. EV is characterized by flat warts and pityriasis-like lesions and might be isolated or syndromic, associated with som
Externí odkaz:
https://doaj.org/article/78144104671a4232ad911ced41934618
Autor:
Blanca Garcia-Solis, Ana Van Den Rym, Jareb J. Pérez-Caraballo, Abdulwahab Al–Ayoubi, Anas M. Alazami, Lazaro Lorenzo, Carolina Cubillos-Zapata, Eduardo López-Collazo, Antonio Pérez-Martínez, Luis M. Allende, Janet Markle, Miguel Fernández-Arquero, Silvia Sánchez-Ramón, Maria J. Recio, Jean-Laurent Casanova, Reem Mohammed, Rubén Martinez-Barricarte, Rebeca Pérez de Diego
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The CARD-BCL10-MALT1 (CBM) complex is critical for the proper assembly of human immune responses. The clinical and immunological consequences of deficiencies in some of its components such as CARD9, CARD11, and MALT1 have been elucidated in detail. H
Externí odkaz:
https://doaj.org/article/8741b9bb80a4423bab400712dd1659fa
Autor:
Frédégonde About, Stéphanie Bibert, Emmanuelle Jouanguy, Bertrand Nalpas, Lazaro Lorenzo, Vimel Rattina, Mohammed Zarhrate, Sylvain Hanein, Mona Munteanu, Beat Müllhaupt, David Semela, Nasser Semmo, Jean-Laurent Casanova, Ioannis Theodorou, Philippe Sultanik, Thierry Poynard, Stanislas Pol, Pierre-Yves Bochud, Aurélie Cobat, Laurent Abel, The Swiss Hepatitis C Cohort Study Group, The French ANRS HC EP 26 Genoscan Study Group, Francesco Negro, Antoine Hadengue, Laurent Kaiser, Laura Rubbia-Brandt, Darius Moradpour, Cristina Cellerai, Martin Rickenbach, Andreas Cerny, Gladys Martinetti, Jean-François Dufour, Meri Gorgievski, Virginie Masserey Spicher, Markus Heim, Hans Hirsch, Beat Helbling, Stephan Regenass, Raffaele Malinverni, Guenter Dollenmaier, Gieri Cathomas
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Despite the astonishing progress in treating chronic hepatitis C virus (HCV) infection with direct-acting antiviral agents, liver fibrosis remains a major health concern in HCV infected patients, in particular due to the treatment cost and insufficie
Externí odkaz:
https://doaj.org/article/6902600e7fc6453da39b73b597e71e52
Autor:
Quentin B Vincent, Aziz Belkadi, Cindy Fayard, Estelle Marion, Ambroise Adeye, Marie-Françoise Ardant, Christian R Johnson, Didier Agossadou, Lazaro Lorenzo, Julien Guergnon, Christine Bole-Feysot, Jeremy Manry, Patrick Nitschké, Ioannis Theodorou, Jean-Laurent Casanova, Laurent Marsollier, Annick Chauty, Laurent Abel, Alexandre Alcaïs, Franco-Beninese Buruli Research Group
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 4, p e0006429 (2018)
Buruli ulcer (BU), the third most frequent mycobacteriosis worldwide, is a neglected tropical disease caused by Mycobacterium ulcerans. We report the clinical description and extensive genetic analysis of a consanguineous family from Benin comprising
Externí odkaz:
https://doaj.org/article/2a4aea9d19de4a06a26d84c830577bec
Autor:
Zhiyong Liu, Eduardo J. Garcia Reino, Oliver Harschnitz, Hongyan Guo, Yi-Hao Chan, Noopur V. Khobrekar, Mary L. Hasek, Kerry Dobbs, Darawan Rinchai, Marie Materna, Daniela Matuozzo, Danyel Lee, Paul Bastard, Jie Chen, Yoon Seung Lee, Seong K. Kim, Shuxiang Zhao, Param Amin, Lazaro Lorenzo, Yoann Seeleuthner, Remi Chevalier, Laure Mazzola, Claire Gay, Jean-Louis Stephan, Baptiste Milisavljevic, Soraya Boucherit, Flore Rozenberg, Rebeca Perez de Diego, Richard D. Dix, Nico Marr, Vivien Béziat, Aurelie Cobat, Mélodie Aubart, Laurent Abel, Stephane Chabrier, Gregory A. Smith, Luigi D. Notarangelo, Edward S. Mocarski, Lorenz Studer, Jean-Laurent Casanova, Shen-Ying Zhang
Publikováno v:
Science Immunology. 8
Inborn errors of TLR3-dependent type I IFN immunity in cortical neurons underlie forebrain herpes simplex virus-1 (HSV-1) encephalitis (HSE) due to uncontrolled viral growth and subsequent cell death. We report an otherwise healthy patient with HSE w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::276f4f9077671f7d3a35001fd8415b45
https://doi.org/10.1126/sciimmunol.ade2860
https://doi.org/10.1126/sciimmunol.ade2860
Autor:
Jérémie Rosain, Anna-Lena Neehus, Jérémy Manry, Rui Yang, Jérémie Le Pen, Wassim Daher, Zhiyong Liu, Yi-Hao Chan, Natalia Tahuil, Özden Türel, Mathieu Bourgey, Masato Ogishi, Jean-Marc Doisne, Helena M. Izquierdo, Takayoshi Shirasaki, Tom Le Voyer, Antoine Guérin, Paul Bastard, Marcela Moncada-Vélez, Ji Eun Han, Taushif Khan, Franck Rapaport, Seon-Hui Hong, Andrew Cheung, Kathrin Haake, Barbara C. Mindt, Laura Pérez, Quentin Philippot, Danyel Lee, Peng Zhang, Darawan Rinchai, Fatima Al Ali, Manar Mahmoud Ahmad Ata, Mahbuba Rahman, Jessica N. Peel, Søren Heissel, Henrik Molina, Yasemin Kendir-Demirkol, Rasheed Bailey, Shuxiang Zhao, Jonathan Bohlen, Mathieu Mancini, Yoann Seeleuthner, Marie Roelens, Lazaro Lorenzo, Camille Soudée, María Elvira Josefina Paz, María Laura González, Mohamed Jeljeli, Jean Soulier, Serge Romana, Anne-Sophie L’Honneur, Marie Materna, Rubén Martínez-Barricarte, Mathieu Pochon, Carmen Oleaga-Quintas, Alexandre Michev, Mélanie Migaud, Romain Lévy, Marie-Alexandra Alyanakian, Flore Rozenberg, Carys A. Croft, Guillaume Vogt, Jean-François Emile, Laurent Kremer, Cindy S. Ma, Jörg H. Fritz, Stanley M. Lemon, András N. Spaan, Nicolas Manel, Laurent Abel, Margaret R. MacDonald, Stéphanie Boisson-Dupuis, Nico Marr, Stuart G. Tangye, James P. Di Santo, Qian Zhang, Shen-Ying Zhang, Charles M. Rice, Vivien Béziat, Nico Lachmann, David Langlais, Jean-Laurent Casanova, Philippe Gros, Jacinta Bustamante
Publikováno v:
Cell
Cell, 2023, 186 (3), pp.621-645.e33. ⟨10.1016/j.cell.2022.12.038⟩
Cell, 2023, 186 (3), pp.621-645.e33. ⟨10.1016/j.cell.2022.12.038⟩
Inborn errors of human IFN-γ-dependent macrophagic immunity underlie mycobacterial diseases, whereas inborn errors of IFN-α/β-dependent intrinsic immunity underlie viral diseases. Both types of IFNs induce the transcription factor IRF1. We describ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4a4bba1d777506cff9bef2fad8f1ed
https://hal-pasteur.archives-ouvertes.fr/pasteur-04130575
https://hal-pasteur.archives-ouvertes.fr/pasteur-04130575
Autor:
Cecilia B. Korol, Serkan Belkaya, Fahad Alsohime, Lazaro Lorenzo, Stéphanie Boisson-Dupuis, Joseph Brancale, Anna-Lena Neehus, Silvia Vilarinho, Alsum Zobaida, Rabih Halwani, Saleh Al-Muhsen, Jean-Laurent Casanova, Emmanuelle Jouanguy
Publikováno v:
Journal of Clinical Immunology
Fulminant viral hepatitis (FVH) caused by hepatitis A virus (HAV) is a life-threatening disease that typically strikes otherwise healthy individuals. The only known genetic etiology of FVH is inherited IL-18BP deficiency, which unleashes IL-18-depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4459f511cf19b089f64d367eb35fc39b
https://hdl.handle.net/11693/112035
https://hdl.handle.net/11693/112035
Autor:
Peng Zhang, Shen-Ying Zhang, Laurent Abel, Clémentine Boccon-Gibod, Yuval Itan, Jean-Laurent Casanova, Burkhard Stüve, Cigdem Sevim Bayrak, Lazaro Lorenzo, Louis Vallée, Daniela Matuozzo, Yoon-Seung Lee, Soraya Boucherit, Yiming Wu, Aurélie Cobat, Aayushee Jain, Stéphane Chabrier
Publikováno v:
Am J Hum Genet
The human genetic dissection of clinical phenotypes is complicated by genetic heterogeneity. Gene burden approaches that detect genetic signals in case-control studies are underpowered in genetically heterogeneous cohorts. We therefore developed a ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bda62547b70398a813e3ef2b1b4fde8
https://doi.org/10.1016/j.ajhg.2021.04.023
https://doi.org/10.1016/j.ajhg.2021.04.023
Autor:
Paul Bastard, Kuang-Chih Hsiao, Qian Zhang, Jeremy Choin, Emma Best, Jie Chen, Adrian Gervais, Lucy Bizien, Marie Materna, Christine Harmant, Maguelonne Roux, Nicola L. Hawley, Daniel E. Weeks, Stephen T. McGarvey, Karla Sandoval, Carmina Barberena-Jonas, Consuelo D. Quinto-Cortés, Erika Hagelberg, Alexander J. Mentzer, Kathryn Robson, Boubacar Coulibaly, Yoann Seeleuthner, Benedetta Bigio, Zhi Li, Gilles Uzé, Sandra Pellegrini, Lazaro Lorenzo, Zineb Sbihi, Sylvain Latour, Marianne Besnard, Tiphaine Adam de Beaumais, Evelyne Jacqz Aigrain, Vivien Béziat, Ranjan Deka, Litara Esera Tulifau, Satupa‘itea Viali, Muagututi‘a Sefuiva Reupena, Take Naseri, Peter McNaughton, Vanessa Sarkozy, Jane Peake, Annaliesse Blincoe, Sarah Primhak, Simon Stables, Kate Gibson, See-Tarn Woon, Kylie Marie Drake, Adrian V.S. Hill, Cheng-Yee Chan, Richard King, Rohan Ameratunga, Iotefa Teiti, Maite Aubry, Van-Mai Cao-Lormeau, Stuart G. Tangye, Shen-Ying Zhang, Emmanuelle Jouanguy, Paul Gray, Laurent Abel, Andrés Moreno-Estrada, Ryan L. Minster, Lluis Quintana-Murci, Andrew C. Wood, Jean-Laurent Casanova
Publikováno v:
Journal of Experimental Medicine
Journal of Experimental Medicine, 2022, 219 (6), pp.e20220028. ⟨10.1084/jem.20220028⟩
Journal of Experimental Medicine, Rockefeller University Press, 2022, 219 (6), pp.e20220028. ⟨10.1084/jem.20220028⟩
Journal of Experimental Medicine, 2022, 219 (6), pp.e20220028. ⟨10.1084/jem.20220028⟩
Journal of Experimental Medicine, Rockefeller University Press, 2022, 219 (6), pp.e20220028. ⟨10.1084/jem.20220028⟩
International audience; Globally, autosomal recessive IFNAR1 deficiency is a rare inborn error of immunity underlying susceptibility to live attenuated vaccine and wild-type viruses. We report seven children from five unrelated kindreds of western Po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537091812f91c1b04b5f26826afe5f5e
https://hal-pasteur.archives-ouvertes.fr/pasteur-03681917
https://hal-pasteur.archives-ouvertes.fr/pasteur-03681917
Autor:
Lazaro Lorenzo, Jean-Laurent Casanova, Carolina Cubillos-Zapata, Eduardo López-Collazo, Anne Puel, Silvia Sánchez-Ramón, Amin Safa, Rebeca Pérez de Diego, María Vela, Antonio Pérez-Martínez, Mukesh Desai, Maria J. Recio, Ana Van Den Rym, Prasad Taur, Vijaya Gowri, Ambreen Pandrowala, Rubén Martínez-Barricarte, Pablo Gonzalez-Navarro, Victor Toledano
Publikováno v:
Journal of Clinical Immunology. 40:388-398
In 2014, a child with broad combined immunodeficiency (CID) who was homozygous for a private BCL10 allele was reported to have complete inherited human BCL10 deficiency. In the present study, we report a new BCL10 mutation in another child with CID w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612b8a5d42d77a3206304fe4070eeb07
https://doi.org/10.1007/s10875-020-00760-3
https://doi.org/10.1007/s10875-020-00760-3