Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Lazaro Emilio Aira"'
Autor:
Shannon Eileen McGettigan, Lazaro Emilio Aira, Gaurav Kumar, Romain Ballet, Eugene C. Butcher, Nicole Baumgarth, Gudrun F. Debes
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract IL-10+ B cells are critical for immune homeostasis and restraining immune responses in infection, cancer, and inflammation; however, the signals that govern IL-10+ B cell differentiation are ill-defined. Here we find that IL-10+ B cells expa
Externí odkaz:
https://doaj.org/article/4b636fe12b824d0485d4e18d2d529d62
Autor:
Lazaro Emilio Aira, Gudrun F. Debes
Publikováno v:
Journal of Investigative Dermatology. 141:1995-2005.e6
Pro and anti-inflammatory B-cell subsets that localize to unperturbed and inflamed skin are newly emerging components of the skin immune system. To test the relevance of regulatory B cells (Bregs) in the suppression of cutaneous inflammation, we aske
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1113afad4fcc52730dd88ebfe9a2ef09
https://doi.org/10.1016/j.jid.2021.01.013
https://doi.org/10.1016/j.jid.2021.01.013
Autor:
Lazaro Emilio Aira, Gudrun F. Debes
Publikováno v:
The Journal of investigative dermatology. 139(7)
Melanoma is one of the deadliest cancers. In this issue, Kobayashi et al. (2019) demonstrate a novel role for tumor-infiltrating innate-like B1a B cells in promoting melanoma growth. IL-10+ (B1a) regulatory B cells accumulate selectively in melanomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b96fc370cc19223aa2cc9233f4183559
https://pubmed.ncbi.nlm.nih.gov/30836062
https://pubmed.ncbi.nlm.nih.gov/30836062
Autor:
Laurent Boyer, Camila Rubio-Patiño, Johanna Chiche, Arnaud Jacquel, Maeva Gesson, Sandrine Marchetti, Pascal Colosetti, Guillaume Robert, Thierry Passeron, Jozef P. Bossowski, Jean-Ehrland Ricci, Frederic Luciano, Jean-Paul Ortonne, Laura Mondragón, Jean-Philippe Lacour, Lazaro Emilio Aira, Priscillia Lecucq-Ottavi, Sandrine Obba, R. Paul-Bellon, Béatrice Bailly-Maitre, Diogo Goncalves, Patrick Auberger
Publikováno v:
Journal of Investigative Dermatology
Journal of Investigative Dermatology, Nature Publishing Group, 2019, 139 (6), pp.1306--1317. ⟨10.1016/j.jid.2018.11.031⟩
Journal of Investigative Dermatology, 2019, 139 (6), pp.1306--1317. ⟨10.1016/j.jid.2018.11.031⟩
J Invest Dermatol
J Invest Dermatol, 2019, 139 (6), pp.1306--1317. ⟨10.1016/j.jid.2018.11.031⟩
Journal of Investigative Dermatology, Nature Publishing Group, 2019, 139 (6), pp.1306--1317. ⟨10.1016/j.jid.2018.11.031⟩
Journal of Investigative Dermatology, 2019, 139 (6), pp.1306--1317. ⟨10.1016/j.jid.2018.11.031⟩
J Invest Dermatol
J Invest Dermatol, 2019, 139 (6), pp.1306--1317. ⟨10.1016/j.jid.2018.11.031⟩
International audience; Inflammatory caspases, activated within the inflammasome, are responsible for the maturation and secretion of IL-1beta/IL-18. Although their expression in psoriasis was shown several years ago, little is known about the role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e99030e21e391193532f78a1b1028c
https://hal.archives-ouvertes.fr/hal-02195315
https://hal.archives-ouvertes.fr/hal-02195315
Publikováno v:
The Journal of Immunology. 206:11.06-11.06
B cells continuously recirculate through the skin. However, their localized functions within the cutaneous environment are still largely unknown. A subset of IL-10+ B regulatory cells (Bregs) migrate into inflamed skin in an α4β1-integrin-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91b4d5bc52bb4b8a75d4819558bbbde7
https://doi.org/10.4049/jimmunol.206.supp.11.06
https://doi.org/10.4049/jimmunol.206.supp.11.06
Autor:
Shannon E McGettigan, Lazaro Emilio Aira Diaz, Gaurav Kumar, Nicole Baumgarth, Gudrun Fiona Debes
Publikováno v:
The Journal of Immunology. 206:96.14-96.14
IL-10+ regulatory B cells (Bregs) are increasingly recognized as critical for maintaining immune tolerance, and alterations in Breg numbers can have detrimental effects in inflammatory diseases, infection, and cancer. Bregs are found among most B cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33dfe2f391f968f55b50cc552aa68f83
https://doi.org/10.4049/jimmunol.206.supp.96.14
https://doi.org/10.4049/jimmunol.206.supp.96.14
Autor:
Pascal Colosetti, Emma Proïcs, Frederic Luciano, Jean-Ehrland Ricci, Guillaume Robert, Lazaro Emilio Aira, Fabien Gautier, Laurie Signetti, Sandrine Marchetti, Philippe Juin, Parvati Gamas, Elodie Villa, Sandrine Obba, Béatrice Bailly-Maitre, Arnaud Jacquel, Patrick Auberger
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2018, 37 (16), pp.2122-2136. 〈10.1038/s41388-017-0112-0〉
Oncogene, 2018, 37 (16), pp.2122-2136. ⟨10.1038/s41388-017-0112-0⟩
Oncogene, Nature Publishing Group, 2018, 37 (16), pp.2122-2136. ⟨10.1038/s41388-017-0112-0⟩
Oncogene, Nature Publishing Group, 2018, 37 (16), pp.2122-2136. 〈10.1038/s41388-017-0112-0〉
Oncogene, 2018, 37 (16), pp.2122-2136. ⟨10.1038/s41388-017-0112-0⟩
Oncogene, Nature Publishing Group, 2018, 37 (16), pp.2122-2136. ⟨10.1038/s41388-017-0112-0⟩
International audience; Phosphorylation of Ser/Thr residues is a well-established modulating mechanism of the pro-apoptotic function of the BH3-only protein Bim. However, nothing is known about the putative tyrosine of this Bcl-2 family member and it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3ffba65a232f2766b2ecd1a5da94f33
http://www.hal.inserm.fr/inserm-01814383
http://www.hal.inserm.fr/inserm-01814383
Autor:
Isabelle Dugail, Nemanja Vujic, Paul Dasilva-Jardine, Andrea E. Bochem, Kees Hovingh, Emmanuel L. Gautier, Fabienne Foufelle, Thibault Barouillet, François Orange, Madalina Duta-Mare, Manon Viaud, Laurent Yvan-Charvet, Lazaro Emilio Aira, Laurent Boyer, Christian Stehlik, Sandrine Marchetti, Edward B. Thorp, Stoyan Ivanov, Elsa Garcia, Dagmar Kratky, Rodolphe Guinamard, Isabelle Hainault
Publikováno v:
Circulation Research
Circulation Research, American Heart Association, 2018, 122 (10), pp.1369-1384. ⟨10.1161/circresaha.117.312333⟩
Circulation Research, American Heart Association, 2018, 122 (10), pp.1369-1384. ⟨10.1161/circresaha.117.312333⟩
Rationale: Macrophages face a substantial amount of cholesterol after the ingestion of apoptotic cells, and the LIPA (lysosomal acid lipase) has a major role in hydrolyzing cholesteryl esters in the endocytic compartment. Objective: Here, we directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cfb224079933872747e3033b5a053f0
https://europepmc.org/articles/PMC6034181/
https://europepmc.org/articles/PMC6034181/
Autor:
Konstantinos Voutetakis, Els Verhoeyen, Jean-Ehrland Ricci, Laura Mondragón, Cynthia Lebeaupin, Jozef P. Bossowski, Camila Rubio-Patiño, Aristotelis Chatziioannou, François Fenaille, Eric Chevet, Johanna Chiche, Thierry Passeron, Lazaro Emilio Aira, Tony Avril, Gian Marco De Donatis, Sandrine Marchetti, Rana Mhaidly, Florence Castelli, John B. Patterson, Patricia Lamourette, Elodie Villa, Emeline Chu-Van, Béatrice Bailly-Maitre
Publikováno v:
Cell Metabolism
Cell Metabolism, Elsevier, 2018, 27 (4), pp.828-842.e7. ⟨10.1016/j.cmet.2018.02.009⟩
Cell Metabolism, 2018, 27 (4), pp.828-842.e7. ⟨10.1016/j.cmet.2018.02.009⟩
Cell Metabolism, Elsevier, 2018, 27 (4), pp.828-842.e7. ⟨10.1016/j.cmet.2018.02.009⟩
Cell Metabolism, 2018, 27 (4), pp.828-842.e7. ⟨10.1016/j.cmet.2018.02.009⟩
International audience; Dietary restriction (DR) was shown to impact on tumor growth with very variable effects depending on the cancer type. However, how DR limits cancer progression remains largely unknown. Here, we demonstrate that feeding mice a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e54d45e35cd3187a836cfe862d7277b
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01778379
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01778379
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