Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Lazaris-Karatzas A"'
Publikováno v:
In International Journal of Biochemistry and Cell Biology 2001 33(2):133-141
Autor:
Yannick Gachet, Terry Poulton, Ulrich-Axel Bommer, Anthoula Lazaris-Karatzas, Sylvie Tournier, Melanie Lee
Publikováno v:
Europe PubMed Central
The translationally controlled protein P23 was discovered by the early induction of its rate of synthesis after mitogenic stimulation of mouse fibroblasts. P23 is expressed in almost all mammalian tissues and it is highly conserved between animals, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf0ebb80cf40f01148cf46c6f885ff8
https://doi.org/10.1242/jcs.112.8.1257
https://doi.org/10.1242/jcs.112.8.1257
Autor:
A W K S Marinelli, W. K. de Roos, Steve J. Cramer, B Alting von Geusau, Frits J. Fallaux, Rob C. Hoeben, OT Terpstra, M. M. Van Der Eb, A. Lazaris-Karatzas
Publikováno v:
Gene Therapy. 4:55-62
Targeted gene delivery is essential for gene therapy involving in vivo gene transfer. In the present study we analyzed the efficiency and tissue-specificity of gene transfer into the liver with recombinant adenoviruses. Adenovirus vectors carrying th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f735d29522de33137c0f9ba674cf9ce
https://doi.org/10.1038/sj.gt.3300362
https://doi.org/10.1038/sj.gt.3300362
Publikováno v:
Molecular and Cellular Biology. 13:7358-7363
Cyclin D1 is a G1-specific cyclin that has been linked to lymphoid, parathyroid, and breast tumors. Recent studies suggested that high protein levels of cyclin D1 are not always produced when cyclin D1 mRNA is overexpressed in transfected cells, sugg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42aea6bdcca1c8163d87e7059cd946ab
https://doi.org/10.1128/mcb.13.12.7358-7363.1993
https://doi.org/10.1128/mcb.13.12.7358-7363.1993
Publikováno v:
The EMBO Journal. 11:4153-4158
Cellular eukaryotic mRNAs (except organellar) contain at the 5' terminus the structure m7(5')Gppp(5')N (where N is any nucleotide), termed cap. Cap recognition by eukaryotic initiation factor eIF-4F plays an important role in regulating the overall r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7a24fb7cb913c2713296f3a5fb1431
https://doi.org/10.1002/j.1460-2075.1992.tb05508.x
https://doi.org/10.1002/j.1460-2075.1992.tb05508.x
Autor:
Nahum Sonenberg, R. M. Frederickson, Jaramillo M, Hsiang-Fu Kung, M. R. Smith, A. Lazaris-Karatzas, Ya-Lun Liu
Publikováno v:
Genes & Development. 6:1631-1642
Translation initiation factor eIF-4E binds to the eukaryotic mRNA 5' cap structure (m7 GpppN, where N is any nucleotide). eIF-4E is a limiting factor in translation and plays a key role in regulation of translation. We have shown previously that over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616c26ed49992bbdfebe06c911c195b2
https://doi.org/10.1101/gad.6.9.1631
https://doi.org/10.1101/gad.6.9.1631
Autor:
A Lazaris-Karatzas, Nahum Sonenberg
Publikováno v:
Molecular and Cellular Biology. 12:1234-1238
We present evidence that eIF-4E, the mRNA 5' cap-binding protein, cooperates with two immortalizing oncogenes, v-myc and E1A, to cause transformation of rat embryo fibroblasts. eIF-4E alone can transform rat embryo fibroblasts when selection is appli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0882131d9e7e20909f403a8f78ef70
https://doi.org/10.1128/mcb.12.3.1234
https://doi.org/10.1128/mcb.12.3.1234
Publikováno v:
Journal of Biological Chemistry. 266:16518-16523
Ornithine aminotransferase (OAT) is a mitochondrial enzyme expressed at high levels in liver, kidney, and retina. To characterize OAT regulation in retinal lines, we have been studying OAT synthesis in retinoblastomas RB355 and Y79. Our previous data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a146a983a4f41d8ad413f67840ababac
https://doi.org/10.1016/s0021-9258(18)55331-x
https://doi.org/10.1016/s0021-9258(18)55331-x
Publikováno v:
The international journal of biochemistrycell biology. 33(2)
The eukaryotic translation initiation factor 4E regulates the proliferation of many cell types. In the present study, the effect of its overexpression on the growth of an immortalized bovine mammary epithelial cell line, MAC-T, has been investigated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5b17373f8d454b92d37858f087a056
https://pubmed.ncbi.nlm.nih.gov/11240370
https://pubmed.ncbi.nlm.nih.gov/11240370
Autor:
Ulrich Bommer, Lazaris-Karatzas A, De Benedetti A, Nürnberg P, Benndorf R, Bielka H, Sonenberg N
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
Synthesis of the mammalian growth-related protein P23 is rapidly induced after serum stimulation of mouse fibroblasts and Ehrlich ascites tumour cells. This induction occurs at the translational level. Growth-induction leads also to an increase in ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7cbd602d4001f731da4d62ec969eede5
https://pubmed.ncbi.nlm.nih.gov/7787881
https://pubmed.ncbi.nlm.nih.gov/7787881